Reactome | ANK1 [cytosol]

ANK1 [cytosol]

Stable Identifier

R-SSC-373619

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

ANK1, F1SE30

Locations in the PathwayBrowser

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Developmental Biology (Sus scrofa)

- Nervous system development (Sus scrofa)
  - Axon guidance (Sus scrofa)
    - L1CAM interactions (Sus scrofa)
      - Neurofascin interactions (Sus scrofa)
        
        Trans-homodimerization of Neurofascin (Sus scrofa)
        
        Neurofascin:Ankyrin-G complex [plasma membrane] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
        
        Trans neurofascin dimer:ankyrin-G [plasma membrane] (Sus scrofa)
        
        Neurofascin:Ankyrin-G complex [plasma membrane] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)

Metabolism of proteins (Sus scrofa)

- Post-translational protein modification (Sus scrofa)
  - Asparagine N-linked glycosylation (Sus scrofa)
    - Transport to the Golgi and subsequent modification (Sus scrofa)
      - ER to Golgi Anterograde Transport (Sus scrofa)
        
        COPI-mediated anterograde transport (Sus scrofa)
        
        ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
        
        ARFGAPs stimulate ARF GTPase activity (Sus scrofa)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
        
        ERGIC-to-Golgi vesicles bind dynein:dynactin (Sus scrofa)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
        
        Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Sus scrofa)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
        
        cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)

Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - ER to Golgi Anterograde Transport (Sus scrofa)
    - COPI-mediated anterograde transport (Sus scrofa)
      - ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
      - ARFGAPs stimulate ARF GTPase activity (Sus scrofa)
        
        RAB1:GTP:GBF1:USO1:ARF:GTP:coatomer:ARFGAP1,2,3:PalmC-YKT6:p24 dimers:cargo:spectrin:ankyrin [endoplasmic reticulum-Golgi intermediate compartment membrane] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
      - ERGIC-to-Golgi vesicles bind dynein:dynactin (Sus scrofa)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
      - Vesicle is tethered through binding GOLGA2:GORASP1, GOLGB1 and the COG complex (Sus scrofa)
        
        RAB1:GTP:USO1 coatomer:PalmC-YKT6:p24 dimers:cargo:anykrin:spectrin:dynein:dynactin:microtubules [transport vesicle] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [transport vesicle] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
      - cis-Golgi t-SNAREs bind YKT6 on tethered vesicle (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:p24 dimers:cargo:spectrin:ankyrin:COG complex:GOLGA2:GORASP1:TMEM115:cis-SNARE complex [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin:COG complex:GOLGA2:GORASP1:GOLGB1:TMEM115 [Golgi membrane] (Sus scrofa)
        
        RAB1:GTP:USO1:coatomer:PalmC-YKT6:p24 dimers:cargo:spectrin:anykrin [Golgi membrane] (Sus scrofa)
        
        ANK1 [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:F1SE30

Gene Names

ANK1

Reference Genes

ENSEMBL:ENSSSCG00000007022.5

UCSC:F1SE30 ANK1

Other Identifiers

100157679

GO:0005515

GO:0005737

GO:0005856

GO:0005886

GO:0006888

GO:0007165

GO:0008092

GO:0008093

GO:0009898

GO:0014731

GO:0016020

GO:0016192

GO:0019899

GO:0019903

GO:0030507

GO:0043005

GO:0043226

GO:0044325

GO:0051117

GO:0060090

GO:0072659

GO:0170014

Ssc.21745.1.S1_at

Participates

as a component of

as an input of

ARFGAP, cargo, v-SNAREs and p24 proteins bind nascent COPI complex (Sus scrofa)

Inferred From

Ankyrin [cytosol] (Homo sapiens)

ANK1 [cytosol] (Homo sapiens)

Cross References

ENSEMBL

ENSSSCT00000007691, ENSSSCG00000007022, ENSSSCP00000007484

VGNC

96344

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