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WNT3A [extracellular region]
Stable Identifier
R-SSC-3247784
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
extracellular region
Synonyms
N4GlycoAsn-PalmS WNT3A, I3LBV3
Locations in the PathwayBrowser
Expand all
Developmental Biology (Sus scrofa)
MITF-M-regulated melanocyte development (Sus scrofa)
Transcriptional and post-translational regulation of MITF-M expression and activity (Sus scrofa)
GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405 (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by WNT (Sus scrofa)
TCF dependent signaling in response to WNT (Sus scrofa)
Canonical WNT signaling through the atypical receptor RYK (Sus scrofa)
RYK-binding WNTs [extracellular region] (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
RYK:WNTs [plasma membrane] (Sus scrofa)
RYK-binding WNTs [extracellular region] (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Sus scrofa)
Beta-catenin is released from the destruction complex (Sus scrofa)
WNT:FZD:p10S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Sus scrofa)
canonical WNTs [extracellular region] (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
DVL recruits GSK3beta:AXIN1 to the receptor complex (Sus scrofa)
WNT:FZD:LRP5/6:DVL [plasma membrane] (Sus scrofa)
WNT:FZD:LRP5/6 [plasma membrane] (Sus scrofa)
canonical WNTs [extracellular region] (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
WNT:FZD:LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Sus scrofa)
WNT:FZD:LRP5/6:DVL [plasma membrane] (Sus scrofa)
WNT:FZD:LRP5/6 [plasma membrane] (Sus scrofa)
canonical WNTs [extracellular region] (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Sus scrofa)
WNT:FZD:LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Sus scrofa)
WNT:FZD:LRP5/6:DVL [plasma membrane] (Sus scrofa)
WNT:FZD:LRP5/6 [plasma membrane] (Sus scrofa)
canonical WNTs [extracellular region] (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
WNT:FZD:p5S/T-LRP5/6:DVL:AXIN:GSK3B [plasma membrane] (Sus scrofa)
canonical WNTs [extracellular region] (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
WNT3A stimulates the caveolin-dependent internalization of FZD5:p-LRP6 (Sus scrofa)
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [plasma membrane] (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
Regulation of FZD by ubiquitination (Sus scrofa)
USP8 deubiquitinates FZD to potentiate WNT signaling (Sus scrofa)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
N4GlycoAsn-PalmS-WNT3A:ub-FZD:LRP5/6 [plasma membrane] (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
ZNRF3 ubiquitinates FZD to promote its downregulation (Sus scrofa)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane] (Sus scrofa)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
N4GlycoAsn-PalmS-WNT3A:ub-FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane] (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
ZNRF3,RNF43 binds the FZD:LRP5/6 receptor complex (Sus scrofa)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane] (Sus scrofa)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
WNT ligand biogenesis and trafficking (Sus scrofa)
secretion of WNT ligands (Sus scrofa)
WNTs [extracellular region] (Sus scrofa)
WNT3A [extracellular region] (Sus scrofa)
External Reference Information
External Reference
UniProt:I3LBV3
Gene Names
WNT3A
Reference Genes
ENSEMBL:ENSSSCG00000029870.4
Other Identifiers
100514950
GO:0001649
GO:0001701
GO:0001756
GO:0001819
GO:0001934
GO:0001947
GO:0002092
GO:0002376
GO:0003713
GO:0005102
GO:0005109
GO:0005125
GO:0005576
GO:0005615
GO:0005886
GO:0006351
GO:0006355
GO:0006366
GO:0007010
GO:0007155
GO:0007368
GO:0007409
GO:0007411
GO:0007498
GO:0007507
GO:0008104
GO:0008283
GO:0008284
GO:0009952
GO:0009986
GO:0010387
GO:0010468
GO:0010628
GO:0010977
GO:0016055
GO:0016192
GO:0019904
GO:0021527
GO:0021766
GO:0021846
GO:0021874
GO:0021904
GO:0022008
GO:0023052
GO:0030097
GO:0030154
GO:0030168
GO:0030182
GO:0030198
GO:0030879
GO:0030890
GO:0030901
GO:0033138
GO:0033278
GO:0034330
GO:0035567
GO:0035914
GO:0036211
GO:0036342
GO:0039706
GO:0042060
GO:0042100
GO:0042472
GO:0042802
GO:0045165
GO:0045202
GO:0045444
GO:0045445
GO:0045595
GO:0045599
GO:0045893
GO:0045944
GO:0048018
GO:0048103
GO:0048337
GO:0048343
GO:0048643
GO:0048697
GO:0048843
GO:0048856
GO:0050768
GO:0050770
GO:0050804
GO:0050807
GO:0055085
GO:0060070
GO:0060923
GO:0061184
GO:0062009
GO:0065003
GO:0070507
GO:0070527
GO:0072659
GO:0090245
GO:0090263
GO:0090676
GO:0098772
GO:0098978
GO:0140110
GO:1903078
GO:1904339
GO:1905539
GO:1905606
GO:1990851
GO:2000049
GO:2000081
GO:2000179
GO:2000347
GO:2000727
GO:2001141
Participates
as a component of
N4GlycoAsn-PalmS-WNT3A:ub-FZD:LRP5/6:ZNRF3/RNF43 [plasma membrane] (Sus scrofa)
N4GlycoAsn-PalmS-WNT3A:FZD:LRP5/6 [plasma membrane] (Sus scrofa)
N4GlycoAsn-PalmS-WNT3A:ub-FZD:LRP5/6 [plasma membrane] (Sus scrofa)
WNT3A:FZD5:p-LRP6:GSK3B:AXIN:CAV1 [plasma membrane] (Sus scrofa)
as a member of
RYK-binding WNTs [extracellular region] (Sus scrofa)
canonical WNTs [extracellular region] (Sus scrofa)
WNTs [extracellular region] (Sus scrofa)
This entity regulates
Negatively
GSK3B phosphorylates p-S409 MITF-M at S397, S401 and S405
(Sus scrofa)
Other forms of this molecule
WNT3A [extracellular exosome]
WNT3A [endocytic vesicle membrane]
WNT3A [early endosome membrane]
WNT3A [endoplasmic reticulum lumen]
WNT3A [Golgi lumen]
WNT3A [plasma membrane]
Inferred From
N4GlycoAsn-PalmS WNT3A [extracellular region]
(Homo sapiens)
Modified Residues
Name
N4-glycosyl-L-asparagine at unknown position
PsiMod Name
N4-glycosyl-L-asparagine
PsiMod Definition
A protein modification that effectively converts an L-asparagine residue to an N4-glycosyl-L-asparagine.
Name
O-palmitoleyl-L-serine at 209 (in Homo sapiens)
Coordinate
209
PsiMod Name
O-palmitoleyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-palmitoleyl-L-serine.
Cross References
OpenTargets
ENSG00000154342
Ensembl
ENSSSCT00000031062
,
ENSSSCG00000029870
,
ENSSSCP00000021525
VGNC
94971
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