Reactome | FCN2 [extracellular region]

FCN2 [extracellular region]

Stable Identifier

R-SSC-2530451-2

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

extracellular region

Synonyms

FCN1, A0A8W4FNY0

Locations in the PathwayBrowser

Expand all

Immune System (Sus scrofa)

- Innate Immune System (Sus scrofa)
  - Complement cascade (Sus scrofa)
    - Initial triggering of complement (Sus scrofa)
      - Conversion of C2 into C2a and C2b (Sus scrofa)
        
        C4 activators [plasma membrane] (Sus scrofa)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Sus scrofa)
        
        Ficolin-1:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Sus scrofa)
        
        FCN1 dodecamer [extracellular region] (Sus scrofa)
        
        FCN1 trimer [extracellular region] (Sus scrofa)
        
        Homologues of FCN1 [extracellular region] (Sus scrofa)
        
        FCN2 [extracellular region] (Sus scrofa)
      - Conversion of C4 into C4a and C4b (Sus scrofa)
        
        C4 activators [plasma membrane] (Sus scrofa)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Sus scrofa)
        
        Ficolin-1:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Sus scrofa)
        
        FCN1 dodecamer [extracellular region] (Sus scrofa)
        
        FCN1 trimer [extracellular region] (Sus scrofa)
        
        Homologues of FCN1 [extracellular region] (Sus scrofa)
        
        FCN2 [extracellular region] (Sus scrofa)
      - Creation of C4 and C2 activators (Sus scrofa)
        
        Lectin pathway of complement activation (Sus scrofa)
        
        Activation of MASPs (Sus scrofa)
        
        MBL2,FCN:MASPs:carbohydrate patterns [plasma membrane] (Sus scrofa)
        
        FCN1 ligands:FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer:4xCa2+ [plasma membrane] (Sus scrofa)
        
        FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Sus scrofa)
        
        FCN1 dodecamer [extracellular region] (Sus scrofa)
        
        FCN1 trimer [extracellular region] (Sus scrofa)
        
        Homologues of FCN1 [extracellular region] (Sus scrofa)
        
        FCN2 [extracellular region] (Sus scrofa)
        
        MBL2,FCN:activated MASPs:carbohydrate patterns [plasma membrane] (Sus scrofa)
        
        Ficolin-1:activated MASP-1:activated MASP-2:Ca2+:ficolin ligand [plasma membrane] (Sus scrofa)
        
        FCN1 dodecamer [extracellular region] (Sus scrofa)
        
        FCN1 trimer [extracellular region] (Sus scrofa)
        
        Homologues of FCN1 [extracellular region] (Sus scrofa)
        
        FCN2 [extracellular region] (Sus scrofa)
        
        Ficolins bind to repetitive carbohydrate structures on the target cell surface (Sus scrofa)
        
        Ficolin-1 binds to molecular patterns on the target cell surface (Sus scrofa)
        
        FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Sus scrofa)
        
        FCN1 dodecamer [extracellular region] (Sus scrofa)
        
        FCN1 trimer [extracellular region] (Sus scrofa)
        
        Homologues of FCN1 [extracellular region] (Sus scrofa)
        
        FCN2 [extracellular region] (Sus scrofa)
        
        FCN1 ligands:FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer:4xCa2+ [plasma membrane] (Sus scrofa)
        
        FCN1 dodecamer:MASP1 dimer:MASP2-1 dimer [extracellular region] (Sus scrofa)
        
        FCN1 dodecamer [extracellular region] (Sus scrofa)
        
        FCN1 trimer [extracellular region] (Sus scrofa)
        
        Homologues of FCN1 [extracellular region] (Sus scrofa)
        
        FCN2 [extracellular region] (Sus scrofa)
  - Neutrophil degranulation (Sus scrofa)
    - Exocytosis of ficolin-rich granule lumen proteins (Sus scrofa)
      - Ficolin-rich granule lumen proteins [extracellular region] (Sus scrofa)
        
        Homologues of FCN1 [extracellular region] (Sus scrofa)
        
        FCN2 [extracellular region] (Sus scrofa)
    - Exocytosis of secretory granule lumen proteins (Sus scrofa)
      - Secretory granule lumen proteins [extracellular region] (Sus scrofa)
        
        Homologues of FCN1 [extracellular region] (Sus scrofa)
        
        FCN2 [extracellular region] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A8W4FNY0

Gene Names

FCN2

Reference Genes

ENSEMBL:ENSSSCG00000023333.4

Other Identifiers

396881

GO:0001867

GO:0002376

GO:0003823

GO:0005576

GO:0006508

GO:0008228

GO:0016192

GO:0043394

GO:0043654

GO:0048306

GO:0050829

GO:0050830

GO:0098542

GO:1903028

GO:1905370

GO:2001065

Ssc.137.1.S1_at

Participates

as a member of

Homologues of FCN1 [extracellular region] (Sus scrofa)

Other forms of this molecule

FCN2 [secretory granule lumen]

FCN2 [ficolin-1-rich granule lumen]

Inferred From

FCN1 [extracellular region] (Homo sapiens)

Cross References

OpenTargets

ENSG00000160339

Ensembl

ENSSSCT00000092213, ENSSSCP00000080882, ENSSSCG00000023333

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