Reactome | phospho-FCER1G [plasma membrane]

phospho-FCER1G [plasma membrane]

Stable Identifier

R-SSC-2454244

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

p-Y65-FCER1G, Q9XSZ6

Locations in the PathwayBrowser

Expand all

Immune System (Sus scrofa)

- Innate Immune System (Sus scrofa)
  - Fc epsilon receptor (FCERI) signaling (Sus scrofa)
    - FCERI mediated Ca+2 mobilization (Sus scrofa)
      - Phosphorylation of TEC kinases by p-SYK (Sus scrofa)
        
        Clustered p:LYN:p-FCERI:IgE:allergen:p-6Y-SYK [plasma membrane] (Sus scrofa)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI [plasma membrane] (Sus scrofa)
        
        p-Y65,Y76-FCERIG dimer [plasma membrane] (Sus scrofa)
        
        phospho-FCER1G [plasma membrane] (Sus scrofa)
    - FCERI mediated MAPK activation (Sus scrofa)
      - Phosphorylation of SHC by SYK kinase (Sus scrofa)
        
        Clustered p:LYN:p-FCERI:IgE:allergen:p-6Y-SYK [plasma membrane] (Sus scrofa)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI [plasma membrane] (Sus scrofa)
        
        p-Y65,Y76-FCERIG dimer [plasma membrane] (Sus scrofa)
        
        phospho-FCER1G [plasma membrane] (Sus scrofa)
      - Phosphorylation of SLP-76 by p-SYK (Sus scrofa)
        
        Clustered p:LYN:p-FCERI:IgE:allergen:p-6Y-SYK [plasma membrane] (Sus scrofa)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI [plasma membrane] (Sus scrofa)
        
        p-Y65,Y76-FCERIG dimer [plasma membrane] (Sus scrofa)
        
        phospho-FCER1G [plasma membrane] (Sus scrofa)
    - FCERI mediated NF-kB activation (Sus scrofa)
      - Phosphorylation of PKC-theta (Sus scrofa)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI [plasma membrane] (Sus scrofa)
        
        p-Y65,Y76-FCERIG dimer [plasma membrane] (Sus scrofa)
        
        phospho-FCER1G [plasma membrane] (Sus scrofa)
    - Phosphorylation of LAT by p-SYK (Sus scrofa)
      - Clustered p:LYN:p-FCERI:IgE:allergen:p-6Y-SYK [plasma membrane] (Sus scrofa)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI [plasma membrane] (Sus scrofa)
        
        p-Y65,Y76-FCERIG dimer [plasma membrane] (Sus scrofa)
        
        phospho-FCER1G [plasma membrane] (Sus scrofa)
    - Phosphorylation of beta and gamma subunits by LYN (Sus scrofa)
      - Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI [plasma membrane] (Sus scrofa)
        
        p-Y65,Y76-FCERIG dimer [plasma membrane] (Sus scrofa)
        
        phospho-FCER1G [plasma membrane] (Sus scrofa)
    - Recruitment of SYK to p-FCERI gamma subunit (Sus scrofa)
      - Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI [plasma membrane] (Sus scrofa)
        
        p-Y65,Y76-FCERIG dimer [plasma membrane] (Sus scrofa)
        
        phospho-FCER1G [plasma membrane] (Sus scrofa)
      - Clustered p:LYN:p-FCERI:IgE:allergen:SYK [plasma membrane] (Sus scrofa)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI [plasma membrane] (Sus scrofa)
        
        p-Y65,Y76-FCERIG dimer [plasma membrane] (Sus scrofa)
        
        phospho-FCER1G [plasma membrane] (Sus scrofa)
    - Role of LAT2/NTAL/LAB on calcium mobilization (Sus scrofa)
      - Phosphorylation of NTAL by p-SYK/Lyn (Sus scrofa)
        
        Clustered p:LYN:p-FCERI:IgE:allergen:p-6Y-SYK [plasma membrane] (Sus scrofa)
        
        Allergen:p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-LYN:p-FCERI:IgE aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI aggregate [plasma membrane] (Sus scrofa)
        
        p-FCERI [plasma membrane] (Sus scrofa)
        
        p-Y65,Y76-FCERIG dimer [plasma membrane] (Sus scrofa)
        
        phospho-FCER1G [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:Q9XSZ6

Gene Names

FCER1G

Reference Genes

BioGPS Gene:397406 FCER1G

ENSEMBL:ENSSSCG00000006357

ENSEMBL:ENSSSCG00000006357.6 FCER1G

ENSEMBL:ENSSSCG00070025990.1 FCER1G

KEGG Gene (Sus scrofa):397406 FCER1G

Monarch:397406 FCER1G

NCBI Gene:397406 FCER1G

Reference Transcript

RefSeq:NM_001001265.1 FCER1G

Other Identifiers

397406

GO:0002376

GO:0004888

GO:0005886

GO:0007166

GO:0009986

GO:0016020

GO:0019767

GO:0019863

GO:0023052

GO:0032998

GO:0033001

GO:0038095

GO:0042802

GO:0042803

GO:0045087

GO:0060089

GO:0098542

GO:0098797

Ssc.508.1.S1_at

Participates

as a component of

p-Y65,Y76-FCERIG dimer [plasma membrane] (Sus scrofa)

Other forms of this molecule

FCER1G [ficolin-1-rich granule membrane]

FCER1G [tertiary granule membrane]

FCER1G [plasma membrane]

phospho-FCER1G [plasma membrane]

Inferred From

p-Y65-FCER1G [plasma membrane] (Homo sapiens)

Modified Residues

Name

O4'-phospho-L-tyrosine at 65 (in Homo sapiens)

Coordinate

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_001001265.1

OpenTargets

ENSG00000158869

Ensembl

ENSSSCP00000030545, ENSSSCT00000033667, ENSSSCG00000006357

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