Reactome | phospho-PARD6A [plasma membrane]

phospho-PARD6A [plasma membrane]

Stable Identifier

R-SSC-2134533

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

p-S345-PARD6A, A0A286ZZ01

Locations in the PathwayBrowser

Expand all

Signal Transduction (Sus scrofa)

- Signaling by TGFB family members (Sus scrofa)
  - Signaling by TGF-beta Receptor Complex (Sus scrofa)
    - TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Sus scrofa)
      - Disassembly of tight junctions (Sus scrofa)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Sus scrofa)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Sus scrofa)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Sus scrofa)
        
        Tight Junction Complex:p-PARD6A:RHOA [cell junction] (Sus scrofa)
        
        PARD3:p-PARD6A:PRKCZ [cell junction] (Sus scrofa)
        
        phospho-PARD6A [plasma membrane] (Sus scrofa)
      - SMURF1 binds phosphorylated PARD6A (Sus scrofa)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Sus scrofa)
        
        Tight Junction Complex:p-PARD6A:RHOA [cell junction] (Sus scrofa)
        
        PARD3:p-PARD6A:PRKCZ [cell junction] (Sus scrofa)
        
        phospho-PARD6A [plasma membrane] (Sus scrofa)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Sus scrofa)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Sus scrofa)
        
        Tight Junction Complex:p-PARD6A:RHOA [cell junction] (Sus scrofa)
        
        PARD3:p-PARD6A:PRKCZ [cell junction] (Sus scrofa)
        
        phospho-PARD6A [plasma membrane] (Sus scrofa)
      - SMURF1 ubiquitinates RHOA (Sus scrofa)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Sus scrofa)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Sus scrofa)
        
        Tight Junction Complex:p-PARD6A:RHOA [cell junction] (Sus scrofa)
        
        PARD3:p-PARD6A:PRKCZ [cell junction] (Sus scrofa)
        
        phospho-PARD6A [plasma membrane] (Sus scrofa)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Sus scrofa)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Sus scrofa)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Sus scrofa)
        
        Tight Junction Complex:p-PARD6A:RHOA [cell junction] (Sus scrofa)
        
        PARD3:p-PARD6A:PRKCZ [cell junction] (Sus scrofa)
        
        phospho-PARD6A [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A286ZZ01

Gene Names

PARD6A

Reference Genes

ENSEMBL:ENSSSCG00000034863.3

Other Identifiers

100623575

GO:0001933

GO:0005515

GO:0005634

GO:0005737

GO:0005813

GO:0005815

GO:0005856

GO:0005923

GO:0005938

GO:0007010

GO:0007049

GO:0007098

GO:0007163

GO:0016020

GO:0030742

GO:0031267

GO:0034330

GO:0034451

GO:0036211

GO:0043226

GO:0045197

GO:0045217

GO:0050714

GO:0051301

GO:0070161

GO:0120157

GO:1904781

Participates

as a component of

PARD3:p-PARD6A:PRKCZ [cell junction] (Sus scrofa)

Other forms of this molecule

PARD6A [plasma membrane]

PARD6A [cytosol]

Inferred From

p-S345-PARD6A [plasma membrane] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 345 (in Homo sapiens)

Coordinate

345

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

OpenTargets

ENSG00000102981

Ensembl

ENSSSCG00000034863, ENSSSCP00000036871, ENSSSCT00000063616

VGNC

91179

Cite Us!