Reactome | HLA-DOB [lysosomal membrane]

HLA-DOB [lysosomal membrane]

Stable Identifier

R-SSC-2130479

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

lysosomal membrane

Synonyms

HLA class II histocompatibility antigen, DO beta chain precursor, F6PWW7

Locations in the PathwayBrowser

Expand all

Immune System (Sus scrofa)

- Adaptive Immune System (Sus scrofa)
  - MHC class II antigen presentation (Sus scrofa)
    - Disassociation of CLIP from MHC II (Sus scrofa)
      - HLA-DM/HLA-DO [lysosomal membrane] (Sus scrofa)
        
        HLA-DM:HLA-DO [lysosomal membrane] (Sus scrofa)
        
        HLA-DO [lysosomal membrane] (Sus scrofa)
        
        HLA-DOB [lysosomal membrane] (Sus scrofa)
      - peptide free MHC II:HLA-DM [lysosomal membrane] (Sus scrofa)
        
        HLA-DM/HLA-DO [lysosomal membrane] (Sus scrofa)
        
        HLA-DM:HLA-DO [lysosomal membrane] (Sus scrofa)
        
        HLA-DO [lysosomal membrane] (Sus scrofa)
        
        HLA-DOB [lysosomal membrane] (Sus scrofa)
    - Loading of antigenic peptides (Sus scrofa)
      - HLA-DM/HLA-DO [lysosomal membrane] (Sus scrofa)
        
        HLA-DM:HLA-DO [lysosomal membrane] (Sus scrofa)
        
        HLA-DO [lysosomal membrane] (Sus scrofa)
        
        HLA-DOB [lysosomal membrane] (Sus scrofa)
      - peptide free MHC II:HLA-DM [lysosomal membrane] (Sus scrofa)
        
        HLA-DM/HLA-DO [lysosomal membrane] (Sus scrofa)
        
        HLA-DM:HLA-DO [lysosomal membrane] (Sus scrofa)
        
        HLA-DO [lysosomal membrane] (Sus scrofa)
        
        HLA-DOB [lysosomal membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:F6PWW7

Gene Names

HLA-DOB

Reference Genes

ENSEMBL:ENSSSCG00000001459.4

Other Identifiers

100135049

GO:0002250

GO:0002376

GO:0002504

GO:0002587

GO:0005764

GO:0005773

GO:0005886

GO:0006955

GO:0016020

GO:0019882

GO:0023026

GO:0042613

GO:0043226

Participates

as a component of

HLA-DO [lysosomal membrane] (Sus scrofa)

Inferred From

HLA class II histocompatibility antigen, DO beta chain precursor [lysosomal membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000241106

Ensembl

ENSSSCT00000001628, ENSSSCG00000001459, ENSSSCP00000001586

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