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CRK:DOCK180:ELMO1,ELMO2 [cytosol]
Stable Identifier
R-SSC-2029141
Type
Complex
Species
Sus scrofa
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Innate Immune System (Sus scrofa)
Fcgamma receptor (FCGR) dependent phagocytosis (Sus scrofa)
Regulation of actin dynamics for phagocytic cup formation (Sus scrofa)
Activation of RAC1 by CRKII:DOCK180:ELMO (Sus scrofa)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Sus scrofa)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Sus scrofa)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Sus scrofa)
Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Sus scrofa)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Sus scrofa)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Sus scrofa)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by Non-Receptor Tyrosine Kinases (Sus scrofa)
Signaling by PTK6 (Sus scrofa)
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Sus scrofa)
Activation of RAC1 by the PXN:CRK complex (Sus scrofa)
p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Sus scrofa)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Sus scrofa)
Phosphorylated PXN recruits the CRK complex (Sus scrofa)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Sus scrofa)
p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Sus scrofa)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by VEGF (Sus scrofa)
VEGFA-VEGFR2 Pathway (Sus scrofa)
DOCK180:ELMO binds CRK (Sus scrofa)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Sus scrofa)
DOCK180:ELMO exchanges GTP for GDP, activating RAC1 (Sus scrofa)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Sus scrofa)
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CRK [cytosol]
(Sus scrofa)
DOCK1 [cytosol]
(Sus scrofa)
ELMO1,ELMO2 [cytosol]
(Sus scrofa)
Participates
as a component of
CRK:DOCK180:ELMO1,ELMO2:VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-12Y-BCAR1,VEGFA:p-6Y-VEGFR2:p-SHB:p-7Y-PTK2:SRC-1:HSP90:p-Y31,Y118-PXN [plasma membrane] (Sus scrofa)
CRKII:DOCK180:ELMO complex recruited to phagocytic cup [plasma membrane] (Sus scrofa)
p-Y31,Y118-PXN:CRK:DOCK180:ELMO1,ELMO2 [cytosol] (Sus scrofa)
as an input of
Recruitment of CRKII:DOCK180:ELMO complex to FCGR (Sus scrofa)
Phosphorylated PXN recruits the CRK complex (Sus scrofa)
Inferred From
CRK:DOCK180:ELMO1,ELMO2 [cytosol]
(Homo sapiens)
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