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CREBBP [nucleoplasm]
Stable Identifier
R-SSC-193545
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
nucleoplasm
Synonyms
CREBBP, F1RK46
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to chemical stress (Sus scrofa)
KEAP1-NFE2L2 pathway (Sus scrofa)
Nuclear events mediated by NFE2L2 (Sus scrofa)
CREBBP, EP300 acetylates NFE2L2 (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
p-AcK-NFE2L2:CREBBP, EP300 [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
p-NFE2L2:CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
NFE2L2 binds CREBBP,EP300 (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
p-NFE2L2:CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Cellular response to heat stress (Sus scrofa)
HSF1-dependent transactivation (Sus scrofa)
Attenuation phase (Sus scrofa)
HSF1 acetylation at Lys80 (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Cellular response to hypoxia (Sus scrofa)
Regulation of gene expression by Hypoxia-inducible Factor (Sus scrofa)
Formation of HIF:CBP:p300 complex at promoters (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
HIF:CBP:p300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Developmental Biology (Sus scrofa)
MITF-M-regulated melanocyte development (Sus scrofa)
Transcriptional and post-translational regulation of MITF-M expression and activity (Sus scrofa)
CREBBP acetylates HINT1 dimer (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
HINT1 binds MITF-M (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Gene expression (Transcription) (Sus scrofa)
Epigenetic regulation of gene expression (Sus scrofa)
Epigenetic regulation by WDR5-containing histone modifying complexes (Sus scrofa)
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Sus scrofa)
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes (Sus scrofa)
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis (Sus scrofa)
Coactivators are recruited to liganded PPARG:RXRA heterodimer (Sus scrofa)
Activated PPARG:RXRA:adipogenesis genes:Nucleosomes [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:ACSL1 gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:ADIPOQ gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:AGPAT2 gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:ANGPTL4 gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:CD36 gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:CEBPA gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:CIDEC gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:DGAT2 gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:FABP4 gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:LIPE gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:LPIN1 gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:LPL gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:MGLL gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:PDK4 gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:PEX11A gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:PLIN1 gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:PLIN2 gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:PLIN4 gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:PNPLA2 gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:PPARG gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated PPARG:RXRA:SCD gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated p-Y78,Y102-PPARG2:RXRA:ACSS3 gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated p-Y78,Y102-PPARG2:RXRA:ELOVL5 gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated p-Y78,Y102-PPARG2:RXRA:GPAM gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated p-Y78,Y102-PPARG2:RXRA:SCD5 gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Activated p-Y78,Y102-PPARG2:RXRA:THRSP gene:nucleosomes [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
FOXO-mediated transcription (Sus scrofa)
Regulation of FOXO transcriptional activity by acetylation (Sus scrofa)
CREBBP binds FOXO1 (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
FOXO1:CREBBP [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Notch-HLH transcription pathway (Sus scrofa)
Formation of CSL-NICD coactivator complex (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
CSL NICD coactivator complex [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Transcriptional regulation by RUNX1 (Sus scrofa)
RUNX1 regulates transcription of genes involved in differentiation of myeloid cells (Sus scrofa)
RUNX1:CBFB binds CREBBP (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:CREBBP [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Transcriptional regulation by RUNX3 (Sus scrofa)
RUNX3 regulates NOTCH signaling (Sus scrofa)
RUNX3 binds the NOTCH1 coactivator complex (Sus scrofa)
NOTCH1 Coactivator Complex [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
RUNX3:NOTCH1 Coactivator Complex [nucleoplasm] (Sus scrofa)
NOTCH1 Coactivator Complex [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Sus scrofa)
Activation of the TFAP2 (AP-2) family of transcription factors (Sus scrofa)
TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
TFAP2 homo- and heterodimers:CITED2,CITED4,(CITED1):EP300:CREBBP [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Immune System (Sus scrofa)
Innate Immune System (Sus scrofa)
C-type lectin receptors (CLRs) (Sus scrofa)
CD209 (DC-SIGN) signaling (Sus scrofa)
CBP and p300 binds NF-kB complex (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
NFKB1:p-S276-RELA:p300/CBP [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
p300 acetylates RELA subunit (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
NFKB1:p-S276,5AcK-RELA:p300/CBP [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
NFKB1:p-S276-RELA:p300/CBP [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Cytosolic sensors of pathogen-associated DNA (Sus scrofa)
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Sus scrofa)
Beta-catenin enhances association of IRF3 with CBP/p300 (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
beta-catenin:IRF3:p300 [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Sus scrofa)
TRAF6 mediated IRF7 activation (Sus scrofa)
Formation of VAF (virus-activated factor) complex (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
VAF (virus-activated factor) [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
p-IRF7 dimer interacts with coactivator CBP/p300 (Sus scrofa)
CBP/p300:pIRF7:pIRF7 [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
ESR-mediated signaling (Sus scrofa)
Estrogen-dependent gene expression (Sus scrofa)
GREB1 binds ESR1:ESTG and co-activators (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
GREB1:ESR1:ESTG:EP300:CREBBP [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
Signaling by WNT (Sus scrofa)
TCF dependent signaling in response to WNT (Sus scrofa)
Formation of the beta-catenin:TCF transactivating complex (Sus scrofa)
Beta-catenin recruits CBP/p300 (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
TCF/LEF:CTNNB1:CBP/p300 [nucleoplasm] (Sus scrofa)
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
CREBBP [nucleoplasm] (Sus scrofa)
External Reference Information
External Reference
UniProt:F1RK46
Gene Names
CREBBP
Reference Genes
ENSEMBL:ENSSSCG00000007951.6
Other Identifiers
100620215
GO:0000122
GO:0000123
GO:0000785
GO:0001223
GO:0002039
GO:0003677
GO:0003682
GO:0003684
GO:0003712
GO:0003713
GO:0003714
GO:0003824
GO:0004402
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0006325
GO:0006338
GO:0006351
GO:0006355
GO:0008270
GO:0016407
GO:0016479
GO:0016604
GO:0016740
GO:0016746
GO:0023052
GO:0030511
GO:0031648
GO:0031669
GO:0034644
GO:0036211
GO:0038061
GO:0043226
GO:0043229
GO:0043426
GO:0043993
GO:0044017
GO:0044877
GO:0045893
GO:0045944
GO:0046872
GO:0048511
GO:0050896
GO:0061629
GO:0061733
GO:0140096
GO:0140110
GO:0140297
GO:1900182
Ssc.17277.1.S1_at
Participates
as an input of
GREB1 binds ESR1:ESTG and co-activators (Sus scrofa)
CREBBP binds FOXO1 (Sus scrofa)
RUNX1:CBFB binds CREBBP (Sus scrofa)
TFAP2 homo- and heterodimers bind CITED and EP300/CREBBP (Sus scrofa)
Formation of CSL-NICD coactivator complex (Sus scrofa)
Formation of HIF:CBP:p300 complex at promoters (Sus scrofa)
as a component of
GREB1:ESR1:ESTG:EP300:CREBBP [nucleoplasm] (Sus scrofa)
FOXO1:CREBBP [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:CREBBP [nucleoplasm] (Sus scrofa)
TFAP2 homo- and heterodimers:CITED2,CITED4,(CITED1):EP300:CREBBP [nucleoplasm] (Sus scrofa)
CSL NICD coactivator complex [nucleoplasm] (Sus scrofa)
HIF:CBP:p300 [nucleoplasm] (Sus scrofa)
NOTCH1 Coactivator Complex [nucleoplasm] (Sus scrofa)
as a member of
CREBBP,EP300 [nucleoplasm] (Sus scrofa)
Coactivators of PPARalpha [nucleoplasm] (Sus scrofa)
This entity regulates
Negatively
HINT1 binds MITF-M
(Sus scrofa)
Inferred From
CREBBP [nucleoplasm]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000005339
Ensembl
ENSSSCT00000008714
,
ENSSSCP00000008490
,
ENSSSCG00000007951
VGNC
86985
Interactors (2)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q764M6 IRF3
0.524
8
UniProt:Q68871 Q68871
0.524
6
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