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AKR1C4 [cytosol]
Stable Identifier
R-SSC-192142
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
A0A480SLU2
Locations in the PathwayBrowser
Expand all
Drug ADME (Sus scrofa)
Prednisone ADME (Sus scrofa)
AKR1C1 hydrogenates PREDN,PREDL (Sus scrofa)
AKR1C4 [cytosol] (Sus scrofa)
Metabolism (Sus scrofa)
Metabolism of lipids (Sus scrofa)
Fatty acid metabolism (Sus scrofa)
Arachidonic acid metabolism (Sus scrofa)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX) (Sus scrofa)
PGD2 is reduced to 11-epi-PGF2a by AKRIC3 (Sus scrofa)
AKR1C4 [cytosol] (Sus scrofa)
PGH2 is reduced to PGF2a by AKR1C3 (Sus scrofa)
AKR1C4 [cytosol] (Sus scrofa)
Metabolism of steroids (Sus scrofa)
Bile acid and bile salt metabolism (Sus scrofa)
Synthesis of bile acids and bile salts (Sus scrofa)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Sus scrofa)
5Beta-cholestan-7alpha,12alpha,24(S)-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,24(S)-tetrol (Sus scrofa)
AKR1C4 [cytosol] (Sus scrofa)
5beta-cholestan-7alpha,24(S)-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,24(S)-triol (Sus scrofa)
AKR1C4 [cytosol] (Sus scrofa)
Synthesis of bile acids and bile salts via 27-hydroxycholesterol (Sus scrofa)
5Beta-cholestan-7alpha,12alpha,27-triol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,12alpha,27-tetrol (Sus scrofa)
AKR1C4 [cytosol] (Sus scrofa)
5beta-cholestan-7alpha,27-diol-3-one is reduced to 5beta-cholestan-3alpha,7alpha,27-triol (Sus scrofa)
AKR1C4 [cytosol] (Sus scrofa)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Sus scrofa)
5Beta-cholesten-7alpha, 12alpha-diol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha, 12alpha-triol (Sus scrofa)
AKR1C4 [cytosol] (Sus scrofa)
5beta-cholestan-7alpha-ol-3-one is reduced to 5beta-cholestan-3alpha, 7alpha-diol (Sus scrofa)
AKR1C4 [cytosol] (Sus scrofa)
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of fat-soluble vitamins (Sus scrofa)
Retinoid metabolism and transport (Sus scrofa)
AKRs reduce RBP2:atRAL to RBP2:atROL (Sus scrofa)
AKR1C4 [cytosol] (Sus scrofa)
Sensory Perception (Sus scrofa)
Visual phototransduction (Sus scrofa)
Retinoid metabolism and transport (Sus scrofa)
AKRs reduce RBP2:atRAL to RBP2:atROL (Sus scrofa)
AKR1C4 [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
Signaling by Retinoic Acid (Sus scrofa)
RA biosynthesis pathway (Sus scrofa)
AKR1C3 reduces atRAL to atROL (Sus scrofa)
AKR1C4 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A480SLU2
Reference Genes
BioGPS Gene:733694
ENSEMBL:ENSSSCG00000011147
ENSEMBL:ENSSSCG00000011147.4
Monarch:733694
NCBI Gene:733694
Reference Transcript
RefSeq:XM_013980360.1
RefSeq:XM_005668233.2
RefSeq:XM_005668236.2
RefSeq:XM_013980356.1
RefSeq:XM_005668234.2
RefSeq:XM_013980355.1
RefSeq:XM_005668243.2
RefSeq:XM_005668242.2
RefSeq:XM_013980354.1
RefSeq:XM_005668232.2
RefSeq:XM_005668241.2
RefSeq:XM_005668240.2
RefSeq:XM_005668239.2
RefSeq:XM_013980361.1
RefSeq:XM_005668229.2
RefSeq:XM_003482843.2
RefSeq:XM_005668231.2
RefSeq:XM_005668230.1
RefSeq:XM_005668238.2
Other Identifiers
733694
GO:0016491
Inferred From
AKRs [cytosol]
(Homo sapiens)
Aldo-keto reductase family [cytosol]
(Homo sapiens)
AKR1C4 [cytosol]
(Homo sapiens)
AKR1C1 [cytosol]
(Homo sapiens)
AKR1C2 [cytosol]
(Homo sapiens)
AKR1C3 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_005668293.1
,
XP_005668288.1
,
XP_005668287.1
,
XP_005668297.1
,
XP_005668290.1
,
XP_005668298.1
,
XP_005668295.1
,
XP_005668289.1
,
XP_005668296.1
,
XP_013835814.1
,
XP_013835815.1
,
XP_013835808.1
,
XP_013835809.1
,
XP_005668299.1
,
XP_005668291.1
,
XP_005668286.1
,
XP_003482891.1
,
XP_013835810.1
,
XP_005668300.1
Ensembl
ENSSSCP00000042336
,
ENSSSCG00000062058
,
ENSSSCT00000057350
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