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CCNA:p-T160-CDK2 [nucleoplasm]
Stable Identifier
R-SSC-187952
Type
Complex
Species
Sus scrofa
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Cell Cycle, Mitotic (Sus scrofa)
Mitotic G1 phase and G1/S transition (Sus scrofa)
G1/S Transition (Sus scrofa)
Cyclin E associated events during G1/S transition (Sus scrofa)
SCF(Skp2)-mediated degradation of p27/p21 (Sus scrofa)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Sus scrofa)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Sus scrofa)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Sus scrofa)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Sus scrofa)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Sus scrofa)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Ubiquitination of phospho-p27/p21 (Sus scrofa)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Sus scrofa)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Sus scrofa)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Sus scrofa)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Mitotic G2-G2/M phases (Sus scrofa)
G2 Phase (Sus scrofa)
Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2:E2F1/E2F3 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Phosphorylation of E2F1/E2F3 by Cyclin A:phosph-Cdk2(Thr 160) (Sus scrofa)
CCNA:p-T160-CDK2:E2F1/E2F3 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2:p-E2F1/p-E2F3 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
G2/M Transition (Sus scrofa)
Cyclin A/B1/B2 associated events during G2/M transition (Sus scrofa)
CCNA:CDK1/2 complexes and CCNB1:CDK1 complexes phosphorylate FOXM1 (Sus scrofa)
p-CDK1/2:CCNA/p-T161-CDK1:CCNB1 [nucleoplasm] (Sus scrofa)
CCNA:p-CDK1/2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Regulation of mitotic cell cycle (Sus scrofa)
APC/C-mediated degradation of cell cycle proteins (Sus scrofa)
Regulation of APC/C activators between G1/S and early anaphase (Sus scrofa)
Association of Cyclin A:Cdk2 with Cdh1 (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Phosphorylation of Cdh1 by Cyclin A:Cdk2 (Sus scrofa)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
S Phase (Sus scrofa)
Cyclin A:Cdk2-associated events at S phase entry (Sus scrofa)
CAK-mediated phosphorylation of Cyclin A:Cdk2 (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Phosphorylation of proteins involved in the G1/S transition by Cyclin A:Cdk2 (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
SCF(Skp2)-mediated degradation of p27/p21 (Sus scrofa)
Binding of phospho-p27/p21:Cdk2:Cyclin E/A to the SCF(Skp2):Cks1 complex (Sus scrofa)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Sus scrofa)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Cyclin E/A:Cdk2-mediated phosphorylation of p27/p21 (Sus scrofa)
Cyclin E/A:p-T160-CDK2:CDKN1A,CDKN1B [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Degradation of ubiquitinated p27/p21 by the 26S proteasome (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Sus scrofa)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Sus scrofa)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Ubiquitination of phospho-p27/p21 (Sus scrofa)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Sus scrofa)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B:3xubiquitin [nucleoplasm] (Sus scrofa)
Cyclin E/A:CDK2:p-S130-CDKN1A,p-T187-CDKN1B:CUL1:SKP1:SKP2:CKS1B [nucleoplasm] (Sus scrofa)
Cyclin E/A:p-T160-CDK2:p-S130-CDKN1A,p-T187-CDKN1B [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Synthesis of DNA (Sus scrofa)
Switching of origins to a post-replicative state (Sus scrofa)
CDK-mediated phosphorylation and removal of Cdc6 (Sus scrofa)
Cdc6 protein is phosphorylated by CDK (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Orc1 removal from chromatin (Sus scrofa)
Orc1 is phosphorylated by cyclin A/CDK2 (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Chromosome Maintenance (Sus scrofa)
Telomere Maintenance (Sus scrofa)
Extension of Telomeres (Sus scrofa)
Telomere Extension By Telomerase (Sus scrofa)
CDK2:CCNA phosphorylates TERF2 (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Recruitment of Telomerase RNP to the Telomeric Chromosome End (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular Senescence (Sus scrofa)
Senescence-Associated Secretory Phenotype (SASP) (Sus scrofa)
CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CDKN1A (p21) prevents phosphorylation of Cdh1 by Cyclin A:Cdk2 (Sus scrofa)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
DNA Repair (Sus scrofa)
DNA Double-Strand Break Repair (Sus scrofa)
Homology Directed Repair (Sus scrofa)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Sus scrofa)
Processing of DNA double-strand break ends (Sus scrofa)
CDK2 phosphorylates RBBP8 (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
MRN complex binds CDK2 and RBBP8 (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
DNA Replication (Sus scrofa)
Synthesis of DNA (Sus scrofa)
Switching of origins to a post-replicative state (Sus scrofa)
CDK-mediated phosphorylation and removal of Cdc6 (Sus scrofa)
Cdc6 protein is phosphorylated by CDK (Sus scrofa)
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Orc1 removal from chromatin (Sus scrofa)
Orc1 is phosphorylated by cyclin A/CDK2 (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
Regulation of TP53 Activity (Sus scrofa)
Regulation of TP53 Activity through Phosphorylation (Sus scrofa)
CDK2 phosphorylates TP53 (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
Regulation of TP53 Expression and Degradation (Sus scrofa)
Regulation of TP53 Degradation (Sus scrofa)
(CDK1,CDK2):CCNA phosphorylates MDM2 at T218 (Sus scrofa)
CCNA:p-CDK1/2 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CCNA [nucleoplasm]
(Sus scrofa)
phospho-p-T160-CDK2 [nucleoplasm]
(Sus scrofa)
Participates
as an input of
CDKN1A (p21) prevents association of Cyclin A:Cdk2 with Cdh1 (Sus scrofa)
Association of Cyclin A:phospho-Cdk2(Thr 160) with E2F1/E2F3 (Sus scrofa)
Association of Cyclin A:Cdk2 with Cdh1 (Sus scrofa)
MRN complex binds CDK2 and RBBP8 (Sus scrofa)
as a component of
CCNA:p-T160-CDK2:p-E2F1/p-E2F3 [nucleoplasm] (Sus scrofa)
CCNA:p-T160-CDK2:E2F1/E2F3 [nucleoplasm] (Sus scrofa)
Cyclin A:phospho-Cdk2(Thr 160):phospho-Cdh1:phospho-APC/C complex [nucleoplasm] (Sus scrofa)
Cyclin A:phospho-Cdk(Thr 160):Cdh1:phosho-APC/C complex [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:CCNA:p-T160-CDK2:RBBP8 [nucleoplasm] (Sus scrofa)
as an output of
CAK-mediated phosphorylation of Cyclin A:Cdk2 (Sus scrofa)
CDK2 phosphorylates RBBP8 (Sus scrofa)
as a member of
CCNA:p-T160-CDK2,CCNE:p-T160-CDK2 [nucleoplasm] (Sus scrofa)
CCNA:p-CDK1/2 [nucleoplasm] (Sus scrofa)
This entity regulates
Negatively
Recruitment of Telomerase RNP to the Telomeric Chromosome End
(Sus scrofa)
Inferred From
CCNA:p-T160-CDK2 [nucleoplasm]
(Homo sapiens)
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