Reactome | PDGF:Phospho-PDGF receptor dimer [plasma membrane]

PDGF:Phospho-PDGF receptor dimer [plasma membrane]

Stable Identifier

R-SSC-186811

Type

Complex

Species

Sus scrofa

Compartment

plasma membrane

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

Active PDGF dimers (AA, AB, BB) [extracellular region] (Sus scrofa)
Phospho- PDGF receptor dimer [plasma membrane] (Sus scrofa)

Participates

as an input of

SHP2 binds to the active receptor (Sus scrofa)
Grb7 binds to the active PDGF receptor (Sus scrofa)
Nck binds to the active PDGF receptor (Sus scrofa)
Crk binds to the active PDGF receptor (Sus scrofa)
STAT binds to the active receptor (Sus scrofa)
SH2 domain of Src binds to the active receptor (Sus scrofa)
PI3-kinase binds to the active receptor (Sus scrofa)
PLC-gamma binds to the active receptor (Sus scrofa)
GRB2:SOS1 complex binds to the active receptor (Sus scrofa)

as a component of

PDGF:Phospho-PDGF receptor dimer:SHP2 [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Grb7 [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGFR receptor dimer:Nck [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Crk [plasma membrane] (Sus scrofa)
PDGF:phospho-PDGF receptor dimer:STAT [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:MyrG-SRC [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:PLC-gamma [plasma membrane] (Sus scrofa)
PDGF:p-PDGFR dimer:p-PLCgamma [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:Grb2:Sos1 [plasma membrane] (Sus scrofa)
PDGF:Phospho-PDGF receptor dimer:PI3K [plasma membrane] (Sus scrofa)

as an output of

Activated PLC gamma dissociates from the PDGF receptor (Sus scrofa)

Inferred From

PDGF:Phospho-PDGF receptor dimer [plasma membrane] (Homo sapiens)

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