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About
What is Reactome ?
News
Team
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Statistics
Our Logo
License Agreement
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Content
Table of Contents
DOIs
Data Schema
ORCID Integration Project
Docs
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Analysis Service
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Icon Info
Data Model
Computational inferred events
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HIST1H4
Stable Identifier
R-SSC-181902
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
nucleoplasm
Synonyms
P62802
Locations in the PathwayBrowser
Expand all
Cell Cycle (Sus scrofa)
Cell Cycle, Mitotic (Sus scrofa)
M Phase (Sus scrofa)
Mitotic Prophase (Sus scrofa)
Condensation of Prophase Chromosomes (Sus scrofa)
PHF8 demethylates histone H4K20me1 (Sus scrofa)
PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2/3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
SETD8 monomethylates histone H4 (Sus scrofa)
PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2/3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Chromosome Maintenance (Sus scrofa)
Nucleosome assembly (Sus scrofa)
Deposition of new CENPA-containing nucleosomes at the centromere (Sus scrofa)
HJURP:CENPA complex localizes to the centromere (Sus scrofa)
CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA:H4 [nucleoplasm] (Sus scrofa)
HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm] (Sus scrofa)
CENPA:H4 Tetramer [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm] (Sus scrofa)
CENPA:H4 Tetramer [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
New CENPA-containing nucleosomes are deposited at the centromere (Sus scrofa)
CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA:H4 [nucleoplasm] (Sus scrofa)
HJURP:NPM1:RBBP4:RBBP7:RUVBL1:CENPA:H4 [nucleoplasm] (Sus scrofa)
CENPA:H4 Tetramer [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
CCAN:DNA:CASC5:Mis18 complex:HJURP complex:New CENPA nucleosome [nucleoplasm] (Sus scrofa)
Centromeric Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
RSF complex binds the centromere (Sus scrofa)
CCAN:DNA:CASC5:Centromeric nucleosome:RSF complex [nucleoplasm] (Sus scrofa)
Centromeric Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
CCAN:DNA:CASC5:Mis18 complex:HJURP complex:New CENPA nucleosome [nucleoplasm] (Sus scrofa)
Centromeric Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Telomere Maintenance (Sus scrofa)
Packaging Of Telomere Ends (Sus scrofa)
Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure (Sus scrofa)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure (Sus scrofa)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Cellular responses to external stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular Senescence (Sus scrofa)
DNA Damage/Telomere Stress Induced Senescence (Sus scrofa)
Telomere shortening during replicative exhaustion (Sus scrofa)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Oxidative Stress Induced Senescence (Sus scrofa)
KDM6B demethylates H3K27me3 on p16-INK4A promoter (Sus scrofa)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K27me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
CDKN2A Gene:Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Sus scrofa)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K27me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Sus scrofa)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K27me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Sus scrofa)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K27me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
CDKN2A Gene:Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
p-MAPKAPK3 phosphorylates BMI1 (Sus scrofa)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K27me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Sus scrofa)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K27me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Senescence-Associated Secretory Phenotype (SASP) (Sus scrofa)
EHMT1:EHMT2 methylates IL6 promoter (Sus scrofa)
IL6 gene:Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
IL6 gene:Nucleosome-H3K9Me2 [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
EHMT1:EHMT2 methylates IL8 promoter (Sus scrofa)
IL8 gene:Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
IL8 gene:Nucleosome-H3K9Me2 [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Chromatin organization (Sus scrofa)
Chromatin modifying enzymes (Sus scrofa)
HATs acetylate histones (Sus scrofa)
ATF2 acetylates histone H2B, H4 (Sus scrofa)
Histone H2B, H4 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
EP300 acetylates histone H2A, H2B, H3, H4 (Sus scrofa)
Histone H2A, H2B, H3, H4 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
MSL acetylates histone H4 (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
NSL acetylates histone H4 (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Type B histone acetlytransferase complex acetylates histone H4 (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
HDACs deacetylate histones (Sus scrofa)
HDAC1/2 containing-complexes deacetylate histones (Sus scrofa)
Core histone octamer [nucleoplasm] (Sus scrofa)
Histone H3:H4 tetramer [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
HDAC10 deacetylates histone (Sus scrofa)
Core histone octamer [nucleoplasm] (Sus scrofa)
Histone H3:H4 tetramer [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
HDAC3 containing complexes deacetylate histone (Sus scrofa)
Core histone octamer [nucleoplasm] (Sus scrofa)
Histone H3:H4 tetramer [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
HDAC8 deacetylates histones (Sus scrofa)
Core histone octamer [nucleoplasm] (Sus scrofa)
Histone H3:H4 tetramer [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
HDMs demethylate histones (Sus scrofa)
JMJD6 demethylates MeR4-HIST1H4 (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PHF8 demethylates MeK21-histone H4 (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PKMTs methylate histone lysines (Sus scrofa)
SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20) (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
RMTs methylate histone arginines (Sus scrofa)
COPRS:CCND1:CDK4:PRMT5:pT5-WDR77 methylates arginine-4 of histone H4 (H4R3) (Sus scrofa)
MeR4-HIST1H4, HIST1H4 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PRMT1,PRMT6 methylate arginine-4 of histone H4 (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
DNA Repair (Sus scrofa)
DNA Double-Strand Break Repair (Sus scrofa)
DNA Double Strand Break Response (Sus scrofa)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Sus scrofa)
APBB1 and MAPK8 bind diphosphorylated H2AFX (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome:APBB1:p-T,Y-MAPK8 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
ATM phosphorylates EYA1-4 (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
ATM phosphorylates MDC1 (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:MDC1 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
ATM phosphorylates WHSC1 (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:WHSC1 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
ATM phosphorylates histone H2AFX on S139 at DNA DSBs (Sus scrofa)
DNA DSBs:p-MRN:p-S-1981,Ac-K3016-ATM:KAT5:p-Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
ATM recognizes H2AFX-Nucleosomes (Sus scrofa)
DNA DSBs:p-MRN:p-S-1981,Ac-K3016-ATM:KAT5:p-Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
p-Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
EYA1-4 dephosphorylates tyrosine Y142 of H2AFX (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-S139,Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
MDC1 associates with gamma-H2AFX at nuclear foci (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:MDC1 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
WHSC1 binds DNA DSBs (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:WHSC1 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:p-S102-WHSC1 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1 [nucleoplasm] (Sus scrofa)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
p-S139-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
WICH phosphorylates H2AFX on Y142 (Sus scrofa)
H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
p-Y142-H2AFX-Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Gene expression (Transcription) (Sus scrofa)
Epigenetic regulation of gene expression (Sus scrofa)
Negative epigenetic regulation of rRNA expression (Sus scrofa)
NoRC negatively regulates rRNA expression (Sus scrofa)
MBD2 binds methylcytosine in chromatin (Sus scrofa)
Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Sus scrofa)
Chromatin with H3K9me2, 5mC [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Chromatin with H3K9me2, 5mC [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
SIRT1 negatively regulates rRNA expression (Sus scrofa)
Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) (Sus scrofa)
Chromatin (H3K9me2) [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
eNoSC [nucleoplasm] (Sus scrofa)
Chromatin (H3K9me2) [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
eNoSC deacetylates histone H3 (Sus scrofa)
Chromatin [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Chromatin with acetylated H3 [nucleoplasm] (Sus scrofa)
Nucleosome (H3K9ac, H3K14ac) [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
eNoSC [nucleoplasm] (Sus scrofa)
Chromatin (H3K9me2) [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
eNoSC dimethylates histone H3 at lysine-9 (Sus scrofa)
Chromatin (H3K9me2) [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Chromatin [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
eNoSC [nucleoplasm] (Sus scrofa)
Chromatin (H3K9me2) [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PRC2 methylates histones and DNA (Sus scrofa)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Sus scrofa)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Sus scrofa)
PRC2:Chromatin (5-methylcytosine, H3K27me3) [nucleoplasm] (Sus scrofa)
Chromatin with hemimethylC, H3K27me3 [nucleoplasm] (Sus scrofa)
Nucleosome with H3K27me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Sus scrofa)
PRC2 Core:Chromatin [nucleoplasm] (Sus scrofa)
Chromatin [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PRC2 recruits DNA methyltransferases (Sus scrofa)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Sus scrofa)
PRC2 Core:Chromatin [nucleoplasm] (Sus scrofa)
Chromatin [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PRC2 Core:Chromatin [nucleoplasm] (Sus scrofa)
Chromatin [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PRC2 trimethylates histone H3 at lysine-27 (Sus scrofa)
PRC2:Chromatin (H3K27me3) [nucleoplasm] (Sus scrofa)
Chromatin with trimethylated H3K27 [nucleoplasm] (Sus scrofa)
Nucleosome with H3K27me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PRC2:Chromatin [nucleoplasm] (Sus scrofa)
Chromatin [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin (Sus scrofa)
Chromatin [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PRC2:Chromatin [nucleoplasm] (Sus scrofa)
Chromatin [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Positive epigenetic regulation of rRNA expression (Sus scrofa)
B-WICH complex positively regulates rRNA expression (Sus scrofa)
B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 (Sus scrofa)
Nucleosome (H3K9ac) [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Gene Silencing by RNA (Sus scrofa)
Transcriptional regulation by small RNAs (Sus scrofa)
AGO1,2:small RNA complexes interact with chromatin (Sus scrofa)
AGO1,2:miRNA:chromatin:RNA pol II [nucleoplasm] (Sus scrofa)
Chromatin [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Chromatin [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
RNA Polymerase I Transcription (Sus scrofa)
RNA Polymerase I Chain Elongation (Sus scrofa)
Elongation of pre-rRNA transcript (Sus scrofa)
Chromatin (H3K9me2):CBX3 [nucleoplasm] (Sus scrofa)
Chromatin (H3K9me2) [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
RNA Polymerase I Promoter Clearance (Sus scrofa)
RNA Polymerase I Promoter Opening (Sus scrofa)
UBF-1 Binds rDNA Promoter (Sus scrofa)
Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Sus scrofa)
Chromatin with H3K9me2, 5mC [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional regulation by RUNX1 (Sus scrofa)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Sus scrofa)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Sus scrofa)
H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Sus scrofa)
H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Sus scrofa)
H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Sus scrofa)
H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
SUMOylation (Sus scrofa)
SUMO E3 ligases SUMOylate target proteins (Sus scrofa)
SUMOylation of chromatin organization proteins (Sus scrofa)
SUMOylation of Histone H4 with SUMO1 (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
SUMOylation of Histone H4 with SUMO3 (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
ESR-mediated signaling (Sus scrofa)
Estrogen-dependent gene expression (Sus scrofa)
EP300 is recruited to MYC and BCL2 genes (Sus scrofa)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Sus scrofa)
HIST1H2AC nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
MYC gene, BCL2 gene:HIST1H2AC nuclesome:ESR1:ESTG:EP300 [nucleoplasm] (Sus scrofa)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Sus scrofa)
HIST1H2AC nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Sus scrofa)
KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Sus scrofa)
KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
FOXA1 and GATA3 bind to CCND1 promoter (Sus scrofa)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm] (Sus scrofa)
Nucleosome with H3K4me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
KDM1A demethylates H3 on MYC and BCL genes in response to estrogen (Sus scrofa)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Sus scrofa)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
MYC gene, BCL2 gene:HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Sus scrofa)
HIST1H2AC nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
KDM1A is recruited to MYC and BCL2 genes (Sus scrofa)
MYC gene, BCL2 gene: H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG:KDM1A [nucleoplasm] (Sus scrofa)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Sus scrofa)
KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Sus scrofa)
KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
KDM4B-regulated genes:nucleosome:ESR1:ESTG [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
NR5A2, ZNF217 and NCOA3 bind GREB1 promoter (Sus scrofa)
GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
GREB1 gene:nucleosome:ESR1:ESTG:ZNF217:NCOA3:NR5A2 [nucleoplasm] (Sus scrofa)
GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Sus scrofa)
Nucleosome [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes (Sus scrofa)
MYC gene, BCL2 gene: H3K9me2 nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
MYC gene, BLC2 gene:H3K9me2, HIST1H2AC nucleosome:ESR1:ESTG [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Signaling by Rho GTPases (Sus scrofa)
RHO GTPase Effectors (Sus scrofa)
RHO GTPases activate PKNs (Sus scrofa)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Sus scrofa)
Demethylase KDM1A binds KLK2 and KLK3 promoters (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Sus scrofa)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Sus scrofa)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Demethylase KDM4C binds KLK2 and KLK3 promoters (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C [nucleoplasm] (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Sus scrofa)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Sus scrofa)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Sus scrofa)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Sus scrofa)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Sus scrofa)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Sus scrofa)
Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-H3 [nucleoplasm] (Sus scrofa)
Nucleosome with p-T12-H3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Sus scrofa)
Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C [nucleoplasm] (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Sus scrofa)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Sus scrofa)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Sus scrofa)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Sus scrofa)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Sus scrofa)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Sus scrofa)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Sus scrofa)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Sus scrofa)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Sus scrofa)
Nucleosome with H3K9me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
Signaling by WNT (Sus scrofa)
TCF dependent signaling in response to WNT (Sus scrofa)
Formation of the beta-catenin:TCF transactivating complex (Sus scrofa)
SET1 complex trimethylates H3K4 at the MYC gene (Sus scrofa)
MYC gene: H2B K121ub nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H2BK121ub [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
MYC gene:H2B K121ub H3K4me3 nucleosome [nucleoplasm] (Sus scrofa)
Nucleosome with H2BK121ub and H3K4me3 [nucleoplasm] (Sus scrofa)
HIST1H4 [nucleoplasm] (Sus scrofa)
External Reference Information
External Reference
UniProt:P62802
Reference Genes
BioGPS Gene:100158117
dbSNP Gene:100158117
ENSEMBL:ENSSSCG00000031751
ENSEMBL:ENSSSCG00000031751
ENSEMBL:ENSSSCG00000032640
ENSEMBL:ENSSSCG00000032640
ENSEMBL:ENSSSCG00000033065
ENSEMBL:ENSSSCG00000033065
ENSEMBL:ENSSSCG00000033566
ENSEMBL:ENSSSCG00000033566
ENSEMBL:ENSSSCG00000034136
ENSEMBL:ENSSSCG00000034136
ENSEMBL:ENSSSCG00000034688
ENSEMBL:ENSSSCG00000034688
ENSEMBL:ENSSSCG00000035473
ENSEMBL:ENSSSCG00000035473
ENSEMBL:ENSSSCG00000036093
ENSEMBL:ENSSSCG00000036093
ENSEMBL:ENSSSCG00000037864
ENSEMBL:ENSSSCG00000037864
KEGG Gene (Sus scrofa):ssc:100158117
Monarch:100158117
NCBI Gene:100158117
Reference Transcript
RefSeq:XM_001927950.5
RefSeq:XM_013977506.1
RefSeq:XM_005665661.2
RefSeq:XM_013997198.1
Other Identifiers
100621389
110261477
110261487
110261673
110261674
110261675
ENSSSCG00000031751
ENSSSCG00000032640
ENSSSCG00000033065
ENSSSCG00000033566
ENSSSCG00000034136
ENSSSCG00000034688
ENSSSCG00000035473
ENSSSCG00000036093
ENSSSCG00000037864
ENSSSCP00000020000
ENSSSCP00000027849
ENSSSCP00000031770
ENSSSCP00000033006
ENSSSCP00000035848
ENSSSCP00000043406
ENSSSCP00000047443
ENSSSCP00000047673
ENSSSCP00000058501
ENSSSCT00000029000
ENSSSCT00000030537
ENSSSCT00000044595
ENSSSCT00000048952
ENSSSCT00000054239
ENSSSCT00000056329
ENSSSCT00000058366
ENSSSCT00000061257
ENSSSCT00000065404
EntrezGene:100621389
EntrezGene:110261477
EntrezGene:110261487
EntrezGene:110261673
EntrezGene:110261674
EntrezGene:110261675
GO:0000228
GO:0000786
GO:0000788
GO:0003674
GO:0003677
GO:0005575
GO:0005622
GO:0005623
GO:0005634
GO:0005694
GO:0006334
GO:0006352
GO:0008150
GO:0009058
GO:0022607
GO:0034641
GO:0042393
GO:0043226
GO:0046982
GO:0051276
GO:0065003
IPR001951
IPR004823
IPR009072
IPR019809
LOC100621389
LOC110261477
LOC110261487
LOC110261673
LOC110261674
LOC110261675
PF15511
PR00623
SM00417
SM00803
Ssc.24787.1.A1_at
UPI000000003C
XM_021089930
XM_021098428
XM_021098435
XM_021099847
XM_021099849
XP_020945589
XP_020954087
XP_020954094
XP_020955506
XP_020955508
XP_020955509
Participant Of
hasCandidate
Histone H2A, H2B, H3, H4 [nucleoplasm]
MeR4-HIST1H4, HIST1H4 [nucleoplasm]
hasMember
Histone H2B, H4 [nucleoplasm]
input
MSL acetylates histone H4
NSL acetylates histone H4
PRMT1,PRMT6 methylate arginine-4 of histone H4
SETD8 (KMT5A) methylates lysine-21 of histone H4 (H4K20)
SUMOylation of Histone H4 with SUMO1
SUMOylation of Histone H4 with SUMO3
Type B histone acetlytransferase complex acetylates histone H4
output
JMJD6 demethylates MeR4-HIST1H4
PHF8 demethylates MeK21-histone H4
hasComponent
CENPA:H4 Tetramer [nucleoplasm]
Centromeric Nucleosome [nucleoplasm]
H2AFX-Nucleosome [nucleoplasm]
HIST1H2AC nucleosome [nucleoplasm]
Histone H3:H4 tetramer [nucleoplasm]
Nucleosome (H3K9ac) [nucleoplasm]
Nucleosome (H3K9ac, H3K14ac) [nucleoplasm]
Nucleosome [nucleoplasm]
Nucleosome [nucleoplasm]
Nucleosome with H2BK121ub [nucleoplasm]
Nucleosome with H2BK121ub and H3K4me3 [nucleoplasm]
Nucleosome with H3K27me3 [nucleoplasm]
Nucleosome with H3K4me2 [nucleoplasm]
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm]
Nucleosome with H3K4me2/3 [nucleoplasm]
Nucleosome with H3K4me3 [nucleoplasm]
Nucleosome with H3K9me2 [nucleoplasm]
Nucleosome with H3K9me2 and HIST1H2AC: [nucleoplasm]
Nucleosome with H3K9me3 [nucleoplasm]
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm]
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm]
Nucleosome with p-T12, MeK-10-H3 [nucleoplasm]
Nucleosome with p-T12-H3 [nucleoplasm]
p-S139,Y142-H2AFX-Nucleosome [nucleoplasm]
p-S139-H2AFX-Nucleosome [nucleoplasm]
p-Y142-H2AFX-Nucleosome [nucleoplasm]
Other forms of this molecule
SUMO3-HIST1H4 [nucleoplasm]
SUMO1-HIST1H4 [nucleoplasm]
AcK5,12-HIST1H4A [nucleoplasm]
AcK13-HIST1H4 [nucleoplasm]
AcK6-HIST1H4 [nucleoplasm]
AcK17-HIST1H4 [nucleoplasm]
AcK9-HIST1H4 [nucleoplasm]
Me2K21-HIST1H4 [nucleoplasm]
MeK-HIST1H4A [nucleoplasm]
AcK-HIST1H4 [nucleoplasm]
Me3K21-HIST1H4 [nucleoplasm]
MeR4-HIST1H4 [nucleoplasm]
Me2sR4-HIST1H4 [nucleoplasm]
Me2aR4-HIST1H4 [nucleoplasm]
Inferred From
HIST1H4 [nucleoplasm] (Homo sapiens)
Cross References
RefSeq
XP_001927985.1
,
XP_013832960.1
,
XP_005665718.1
,
XP_013852652.1
© 2018
Reactome
