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phospho-IRF3 [cytosol]
Stable Identifier
R-SSC-166258
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
p-4S,T404-IRF3, K7GM32
Locations in the PathwayBrowser
Expand all
Immune System (Sus scrofa)
Innate Immune System (Sus scrofa)
Cytosolic sensors of pathogen-associated DNA (Sus scrofa)
STING mediated induction of host immune responses (Sus scrofa)
IRF3-mediated induction of type I IFN (Sus scrofa)
Dimerized phospho-IRF3 migrates to the nucleus (Sus scrofa)
p-T,4S-IRF3:p-T,4S-IRF3 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
IRF3 is phosphorylated by TBK1 (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
p-T,4S-IRF3 is dimerized (Sus scrofa)
p-T,4S-IRF3:p-T,4S-IRF3 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
ZBP1(DAI) mediated induction of type I IFNs (Sus scrofa)
IRF3 mediated activation of type 1 IFN (Sus scrofa)
Dimerized phospho-IRF3 migrates to the nucleus (Sus scrofa)
p-T,4S-IRF3:p-T,4S-IRF3 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
p-T,4S-IRF3 is dimerized (Sus scrofa)
p-T,4S-IRF3:p-T,4S-IRF3 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Sus scrofa)
TRAF3-dependent IRF activation pathway (Sus scrofa)
Dimerization of Phospho IRF3 or phospho IRF7 (Sus scrofa)
IRF3-P:IRF7-P [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
p-4S,T404-IRF3,p-S477,S479-IRF7 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
p-T,4S-IRF3:p-T,4S-IRF3 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
Translocation of phosphorylated IRF3,IRF7 dimers into nucleus (Sus scrofa)
IRF3-P:IRF7-P [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
p-T,4S-IRF3:p-T,4S-IRF3 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
Toll-like Receptor Cascades (Sus scrofa)
Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
TICAM1-dependent activation of IRF3/IRF7 (Sus scrofa)
Dimerization of phosphorylated IRF3/IRF7 (Sus scrofa)
p-4S,T404-IRF3,p-S477,S479-IRF7 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
phosphorylated IRF3 and/or IRF7 dimer [cytosol] (Sus scrofa)
p-T,4S-IRF3:p-T,4S-IRF3 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Sus scrofa)
phosphorylated IRF3 and/or IRF7 dimer [cytosol] (Sus scrofa)
p-T,4S-IRF3:p-T,4S-IRF3 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
MyD88-independent TLR4 cascade (Sus scrofa)
TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Sus scrofa)
Dimerization of phosphorylated IRF3/IRF7 (Sus scrofa)
p-4S,T404-IRF3,p-S477,S479-IRF7 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
phosphorylated IRF3 and/or IRF7 dimer [cytosol] (Sus scrofa)
p-T,4S-IRF3:p-T,4S-IRF3 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
Dimerized phospho-IRF3/IRF7 is transported to the nucleus (Sus scrofa)
phosphorylated IRF3 and/or IRF7 dimer [cytosol] (Sus scrofa)
p-T,4S-IRF3:p-T,4S-IRF3 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Sus scrofa)
p-4S,T404-IRF3,p-S477,S479-IRF7 [cytosol] (Sus scrofa)
phospho-IRF3 [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:K7GM32
Gene Names
IRF3
Reference Genes
ENSEMBL:ENSSSCG00000003178.6
Other Identifiers
396656
GO:0000122
GO:0000785
GO:0000976
GO:0000978
GO:0000981
GO:0001216
GO:0001227
GO:0001228
GO:0002376
GO:0002753
GO:0003677
GO:0003700
GO:0005634
GO:0005694
GO:0005737
GO:0005739
GO:0005829
GO:0006351
GO:0006355
GO:0006357
GO:0006954
GO:0009617
GO:0010468
GO:0012501
GO:0019904
GO:0023052
GO:0031663
GO:0032481
GO:0032496
GO:0032727
GO:0032728
GO:0034142
GO:0035666
GO:0042802
GO:0042803
GO:0042981
GO:0043226
GO:0043330
GO:0043565
GO:0045893
GO:0045944
GO:0050727
GO:0051607
GO:0060337
GO:0060340
GO:0071222
GO:0097300
GO:0098542
GO:0098586
GO:0140110
GO:1990837
GO:1990841
Ssc.1783.1.S1_at
Participates
as an input of
p-T,4S-IRF3 is dimerized (Sus scrofa)
as an output of
IRF3 is phosphorylated by TBK1 (Sus scrofa)
as a member of
p-4S,T404-IRF3,p-S477,S479-IRF7 [cytosol] (Sus scrofa)
as a component of
IRF3-P:IRF7-P [cytosol] (Sus scrofa)
p-T,4S-IRF3:p-T,4S-IRF3 [cytosol] (Sus scrofa)
Other forms of this molecule
phospho-IRF3 [nucleoplasm]
phospho-IRF3 [nucleoplasm]
IRF3 [cytosol]
Inferred From
p-4S,T404-IRF3 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 396 (in Homo sapiens)
Coordinate
396
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 398 (in Homo sapiens)
Coordinate
398
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 402 (in Homo sapiens)
Coordinate
402
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 405 (in Homo sapiens)
Coordinate
405
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at 404 (in Homo sapiens)
Coordinate
404
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Cross References
OpenTargets
ENSG00000126456
Ensembl
ENSSSCT00000033478
,
ENSSSCP00000028920
,
ENSSSCG00000003178
VGNC
89206
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