Reactome | A2M tetramer [extracellular region]

A2M tetramer [extracellular region]

Stable Identifier

R-SSC-158255

Type

Complex

Species

Sus scrofa

Compartment

extracellular region

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 4 A2M [extracellular region] (Sus scrofa)

Participates

as an input of

MMP1,3,13 (2, 7-12, 19) binding by Alpha-2 macroglubulin (Sus scrofa)
kallikrein + alpha2-macroglobulin -> kallikrein:alpha2-macrogloulin (Sus scrofa)

as a component of

Alpha 2-macroglobulin:MMP1, 3, 13, (2, 7-12, 19) [extracellular region] (Sus scrofa)
kallikrein:alpha2-macroglobulin [extracellular region] (Sus scrofa)

This entity regulates

Negatively

BMP1-3:Zn2+ cleaves pro-APOA1 to APOA1 (Sus scrofa)

Inferred From

A2M tetramer [extracellular region] (Homo sapiens)

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