Reactome | TRADD:TRAF2:RIPK1:FADD [cytosol]

TRADD:TRAF2:RIPK1:FADD [cytosol]

Stable Identifier

R-SSC-140977

Type

Complex

Species

Sus scrofa

Compartment

cytosol

Locations in the PathwayBrowser

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General

This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.

Participants

components

x 2 TNFRSF6 [cytosol] (Sus scrofa)
TRAF2:TRADD:RIPK1 [cytosol] (Sus scrofa)

Participates

as a component of

TRADD:TRAF2:RIPK1:FADD:p43/p41CASP8:p43 FLIP(L) [plasma membrane] (Sus scrofa)
TRADD:TRAF2:RIP1:FADD:procaspase-8:FLIP(L) [cytosol] (Sus scrofa)
TRADD:TRAF2:RIP1:FADD:CASP8(1-479) [cytosol] (Sus scrofa)
TRAF2:TRADD:RIP1:FADD:2xCASP8(1-479) [cytosol] (Sus scrofa)

as an input of

FLIP(L) and procaspase-8 form heterodimer in TNF signaling (Sus scrofa)
RIPK1 is cleaved by CASP8 (Sus scrofa)

as an output of

TRADD:TRAF2:RIP1 binds FADD (Sus scrofa)

as a member of

DISC [plasma membrane] (Sus scrofa)

Inferred From

TRADD:TRAF2:RIPK1:FADD [cytosol] (Homo sapiens)