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VCP [cytosol]
Stable Identifier
R-SSC-1181251
Type
Protein [EntityWithAccessionedSequence]
Species
Sus scrofa
Compartment
cytosol
Synonyms
VCP, A0A8D1YIJ1
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to chemical stress (Sus scrofa)
KEAP1-NFE2L2 pathway (Sus scrofa)
UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Sus scrofa)
NPLOC4:UFD1:VCP hexamer [cytosol] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Sus scrofa)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Sus scrofa)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
Cellular response to heat stress (Sus scrofa)
HSF1 activation (Sus scrofa)
Dissociation of cytosolic HSF1:HSP90:HDAC6:PTGES3 upon sensing protein aggregates (Sus scrofa)
HDAC6:VCP:protein aggregates [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
Regulation of T cell activation by CD28 family (Sus scrofa)
Co-inhibition by PD-1 (Sus scrofa)
Regulation of PD-L1(CD274) expression (Sus scrofa)
Regulation of PD-L1(CD274) Post-translational modification (Sus scrofa)
AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274) (Sus scrofa)
Active transport of ubiquitinated CD274 from ER to cytosol (Sus scrofa)
ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
Poly-Ub-p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
Ubiquitination of CD274 by ERAD complex (Sus scrofa)
ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
Poly-Ub-p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
p-S195-CD274 binds ERAD complex (Sus scrofa)
ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
p-S195-CD274:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Asparagine N-linked glycosylation (Sus scrofa)
N-glycan trimming in the ER and Calnexin/Calreticulin cycle (Sus scrofa)
Deglycosylation complex hydrolyses N-glycans from unfolded glycoproteins (Sus scrofa)
Deglycosylation complex [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
Deubiquitination (Sus scrofa)
Ovarian tumor domain proteases (Sus scrofa)
YOD1 binds VCP (Sus scrofa)
VCP [cytosol] (Sus scrofa)
YOD1:VCP [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
Neddylation (Sus scrofa)
UBXN7 binds VCP hexamer:UBF1:NPLOC4 (Sus scrofa)
NPLOC4:UFD1:VCP hexamer [cytosol] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
UBXN7:UBF1:NPLOC4:VCP hexamer binds NFE2L2:CRL3 complex (Sus scrofa)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
ub-NFE2L2:KEAP1:NEDD8-CUL3:RBX1:UBXN7:UBF1:NPLOC4:VCP hexamer [cytosol] (Sus scrofa)
UBXN7:NPLOC4:UBF1:VCP hexamer [cytosol] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
Protein methylation (Sus scrofa)
VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Sus scrofa)
VCP [cytosol] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by Hedgehog (Sus scrofa)
Hedgehog ligand biogenesis (Sus scrofa)
C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Sus scrofa)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Sus scrofa)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
SYVN1 ubiquitinates Hh C-terminal fragments (Sus scrofa)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Sus scrofa)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Sus scrofa)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Sus scrofa)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Sus scrofa)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
Signaling by Rho GTPases (Sus scrofa)
RHO GTPase cycle (Sus scrofa)
RHOH GTPase cycle (Sus scrofa)
RHOH binds effectors at the plasma membrane (Sus scrofa)
RHOH effectors [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
RHOH:GTP:RHOH effectors [plasma membrane] (Sus scrofa)
RHOH effectors [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
Transport of small molecules (Sus scrofa)
ABC-family proteins mediated transport (Sus scrofa)
CFTR binds components of the ERAD machinery for ubiquitination and degradation (Sus scrofa)
ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
RNF5 and RNF185 ubiquitinate misfolded CFTR (Sus scrofa)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Sus scrofa)
ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
ERAD complex [endoplasmic reticulum membrane] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
VCP [cytosol] (Sus scrofa)
External Reference Information
External Reference
UniProt:A0A8D1YIJ1
Gene Names
VCP
Reference Genes
ENSEMBL:ENSSSCG00005046199.1
UCSC:A0A8D1YIJ1 VCP
Other Identifiers
397524
GO:0000153
GO:0000166
GO:0000502
GO:0005524
GO:0005634
GO:0005654
GO:0005737
GO:0005783
GO:0005789
GO:0005811
GO:0005815
GO:0005829
GO:0006281
GO:0006302
GO:0006511
GO:0006734
GO:0006886
GO:0006914
GO:0006974
GO:0007010
GO:0007249
GO:0008289
GO:0010494
GO:0010498
GO:0010918
GO:0016192
GO:0016236
GO:0016567
GO:0016787
GO:0016887
GO:0019079
GO:0019903
GO:0019904
GO:0019985
GO:0030163
GO:0030970
GO:0031334
GO:0031593
GO:0031625
GO:0032436
GO:0032510
GO:0032991
GO:0034098
GO:0034605
GO:0035331
GO:0035617
GO:0035800
GO:0035861
GO:0036064
GO:0036435
GO:0036503
GO:0036513
GO:0042288
GO:0042802
GO:0043161
GO:0043226
GO:0043531
GO:0044389
GO:0045202
GO:0045732
GO:0045879
GO:0046034
GO:0048471
GO:0051228
GO:0055086
GO:0060090
GO:0061857
GO:0070842
GO:0071218
GO:0072389
GO:0090263
GO:0097352
GO:0098772
GO:0106300
GO:0120186
GO:0140036
GO:0140455
GO:1901135
GO:1901224
GO:1903006
GO:1903715
GO:1903843
GO:1903862
GO:1904288
GO:1904949
GO:1905634
GO:1990381
GO:1990730
GO:2001171
Ssc.3269.1.S1_at
Ssc.856.1.S1_at
Participates
as a candidate of
RHOH effectors [cytosol] (Sus scrofa)
as an input of
YOD1 binds VCP (Sus scrofa)
VCPKMT (METTL21D) transfers 3xCH3 from 3xAdoMet to VCP (Sus scrofa)
as a component of
YOD1:VCP [cytosol] (Sus scrofa)
HDAC6:VCP:protein aggregates [cytosol] (Sus scrofa)
HSF1:HSP90:HDAC6:VCP:PTGES3 [cytosol] (Sus scrofa)
VCP hexamer [cytosol] (Sus scrofa)
Other forms of this molecule
VCP [cytosol]
VCP [nucleoplasm]
VCP [ficolin-1-rich granule lumen]
VCP [secretory granule lumen]
VCP [extracellular region]
VCP [azurophil granule lumen]
Inferred From
VCP [cytosol]
(Homo sapiens)
Cross References
ENSEMBL
ENSSSCG00000005300
,
ENSSSCP00000073474
,
ENSSSCT00000090983
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