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P-TEFb complex [nucleoplasm]
Stable Identifier
R-SSC-112431
Type
Complex
Species
Sus scrofa
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
TP53 Regulates Transcription of DNA Repair Genes (Sus scrofa)
CCNK:CDK12 binds RNA Pol II at DNA repair genes (Sus scrofa)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Sus scrofa)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Sus scrofa)
CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Sus scrofa)
CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Sus scrofa)
CDK12-phosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Sus scrofa)
Elongation Complex at DNA Repair Genes [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Sus scrofa)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Sus scrofa)
Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Sus scrofa)
CDK8:CCNC/ CDK9:CCNT [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II Pre-transcription Events (Sus scrofa)
2-4 nt.backtracking of Pol II complex on the template leading to elongation pausing (Sus scrofa)
Paused processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
7-14 nt. Backtracking of Pol II complex on the template leading to elongation arrest (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Abortive termination of elongation after arrest (Sus scrofa)
Aborted elongation complex after arrest [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Elongating transcript encounters a lesion in the template (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Formation of P-TEFb complex (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Resumption of elongation after recovery from pausing (Sus scrofa)
Paused processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
TFIIS-mediated recovery of elongation from arrest (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
RNA Polymerase II Transcription Elongation (Sus scrofa)
Addition of nucleotides leads to transcript elongation (Sus scrofa)
Elongation complex [nucleoplasm] (Sus scrofa)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Formation of RNA Pol II elongation complex (Sus scrofa)
Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex (Sus scrofa)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Recruitment of elongation factors to form elongation complex (Sus scrofa)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Elongation complex [nucleoplasm] (Sus scrofa)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Pol II elongation complex moves on the template as transcript elongates (Sus scrofa)
Elongation complex prior to separation [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Separation of elongating transcript from template (Sus scrofa)
Elongation complex prior to separation [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
RNA polymerase II transcribes snRNA genes (Sus scrofa)
CBCAP complex binds 7-methylguanosine cap of snRNA (Sus scrofa)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Sus scrofa)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Sus scrofa)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Integrator complex processes the 3' end of snRNA (Sus scrofa)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:CBCAP:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Pre-snRNA is elongated and capped with 7-methylguanosine (Sus scrofa)
RNA polymerase II (phosphoserine-2,7):RPAP2:Integrator:LEC:capped pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Pre-snRNA transcript initiation, Integrator binding, LEC binding (Sus scrofa)
RNA polymerase II (phosphoserine-5,7):RPRD1A,B:RPRD2:RPAP2:Integrator:LEC:pre-snRNA:Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Sus scrofa)
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Sus scrofa)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
Signal Transduction (Sus scrofa)
Signaling by TGFB family members (Sus scrofa)
Signaling by TGF-beta Receptor Complex (Sus scrofa)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Sus scrofa)
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription (Sus scrofa)
Phosphorylation of SMAD2 and SMAD3 linker regions by CDK8 or CDK9 (Sus scrofa)
CDK8:CCNC/ CDK9:CCNT [nucleoplasm] (Sus scrofa)
P-TEFb complex [nucleoplasm] (Sus scrofa)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
CCNT1,CCNT2,CCNK [nucleoplasm]
(Sus scrofa)
CDK9 [nucleoplasm]
(Sus scrofa)
Participates
as an output of
Elongating transcript encounters a lesion in the template (Sus scrofa)
Formation of P-TEFb complex (Sus scrofa)
as a component of
RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Sus scrofa)
Initiation factors:CDK7:snRNA gene [nucleoplasm] (Sus scrofa)
Aborted elongation complex after arrest [nucleoplasm] (Sus scrofa)
Paused processive elongation complex [nucleoplasm] (Sus scrofa)
Elongation complex with separated and uncleaved transcript [nucleoplasm] (Sus scrofa)
Elongation complex prior to separation [nucleoplasm] (Sus scrofa)
Processive elongation complex [nucleoplasm] (Sus scrofa)
Early elongation complex with hyperphosphorylated Pol II CTD [nucleoplasm] (Sus scrofa)
CDK12-phosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Sus scrofa)
Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Sus scrofa)
as an input of
Hyperphosphorylation (Ser2) of RNA Pol II CTD by P-TEFb complex (Sus scrofa)
as a member of
CDK8:CCNC/ CDK9:CCNT [nucleoplasm] (Sus scrofa)
Inferred From
P-TEFb complex [nucleoplasm]
(Homo sapiens)
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