Reactome | vma16 [lysosomal membrane]

vma16 [lysosomal membrane]

Stable Identifier

R-SPO-9640187

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

lysosomal membrane

Synonyms

ATP6V0B, O14046

Locations in the PathwayBrowser

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Cellular responses to stimuli (Schizosaccharomyces pombe)

- Cellular responses to stress (Schizosaccharomyces pombe)
  - Cellular response to starvation (Schizosaccharomyces pombe)
    - Amino acids regulate mTORC1 (Schizosaccharomyces pombe)
      - RRAGA,B exchanges GDP for GTP (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase [lysosomal membrane] (Schizosaccharomyces pombe)
        
        ATP6V0 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        vma16 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:SLC38A9:Arg [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase [lysosomal membrane] (Schizosaccharomyces pombe)
        
        ATP6V0 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        vma16 [lysosomal membrane] (Schizosaccharomyces pombe)
      - RRAGA,B hydrolyzes GTP (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase [lysosomal membrane] (Schizosaccharomyces pombe)
        
        ATP6V0 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        vma16 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase [lysosomal membrane] (Schizosaccharomyces pombe)
        
        ATP6V0 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        vma16 [lysosomal membrane] (Schizosaccharomyces pombe)
      - RRAGC,D exchanges GTP for GDP (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase [lysosomal membrane] (Schizosaccharomyces pombe)
        
        ATP6V0 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        vma16 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase [lysosomal membrane] (Schizosaccharomyces pombe)
        
        ATP6V0 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        vma16 [lysosomal membrane] (Schizosaccharomyces pombe)
      - RRAGC,D hydrolyzes GTP (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GDP [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase [lysosomal membrane] (Schizosaccharomyces pombe)
        
        ATP6V0 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        vma16 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GDP:RRAGC,D:GTP [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase [lysosomal membrane] (Schizosaccharomyces pombe)
        
        ATP6V0 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        vma16 [lysosomal membrane] (Schizosaccharomyces pombe)
      - mTORC1 binds RHEB:GTP (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase [lysosomal membrane] (Schizosaccharomyces pombe)
        
        ATP6V0 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        vma16 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1:RHEB:GTP [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase [lysosomal membrane] (Schizosaccharomyces pombe)
        
        ATP6V0 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        vma16 [lysosomal membrane] (Schizosaccharomyces pombe)
      - v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP binds mTORC1 (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase [lysosomal membrane] (Schizosaccharomyces pombe)
        
        ATP6V0 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        vma16 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP:mTORC1 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator:RRAGA,B:GTP:RRAGC,D:GDP [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase:Ragulator [lysosomal membrane] (Schizosaccharomyces pombe)
        
        v-ATPase [lysosomal membrane] (Schizosaccharomyces pombe)
        
        ATP6V0 [lysosomal membrane] (Schizosaccharomyces pombe)
        
        vma16 [lysosomal membrane] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:O14046

Gene Names

vma16

Reference Genes

BioGPS Gene:2541999 vma16

ENSEMBL:SPAC2C4.13

GeneDB:SPAC2C4.13

KEGG Gene (Schizosaccharomyces pombe):SPAC2C4.13 vma16

Monarch:2541999 vma16

NCBI Gene:2541999 vma16

Reference Transcript

RefSeq:NM_001019945.2 vma16

Participates

as a component of

ATP6V0 [lysosomal membrane] (Schizosaccharomyces pombe)

Other forms of this molecule

vma16 [phagocytic vesicle membrane]

vma16 [endosome membrane]

Inferred From

ATP6V0B [lysosomal membrane] (Homo sapiens)

Cross References

RefSeq

NP_594516.1

PRO

O14046

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