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pan1 [cytosol]
Stable Identifier
R-SPO-8862264
Type
Protein [EntityWithAccessionedSequence]
Species
Schizosaccharomyces pombe
Compartment
cytosol
Synonyms
ITSN2, Q10172
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Schizosaccharomyces pombe)
Membrane Trafficking (Schizosaccharomyces pombe)
Clathrin-mediated endocytosis (Schizosaccharomyces pombe)
AAK1 phosphorylates AP-2 mu subunit at T156 (Schizosaccharomyces pombe)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Schizosaccharomyces pombe)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
BAR domain proteins recruit dynamin (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
Clathrin recruits auxilins to the clathrin-coated vesicle (Schizosaccharomyces pombe)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Schizosaccharomyces pombe)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Schizosaccharomyces pombe)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
Endophilins recruit synaptojanins to the clathrin-coated pit (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
FCHo proteins bind nascent clathrin-coated pit (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Schizosaccharomyces pombe)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
RAB5 and GAPVD1 bind AP-2 (Schizosaccharomyces pombe)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Schizosaccharomyces pombe)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Schizosaccharomyces pombe)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Schizosaccharomyces pombe)
ITSNs [cytosol] (Schizosaccharomyces pombe)
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
pan1 [cytosol] (Schizosaccharomyces pombe)
External Reference Information
External Reference
UniProt:Q10172
Gene Names
pan1
Reference Genes
ENSEMBL:SPAC25G10.09c
GeneDB:SPAC25G10.09c
Reference Transcript
RefSeq:XM_001713053.2 pan1
Participates
as a member of
Homologues of ITSN2 [cytosol] (Schizosaccharomyces pombe)
Other forms of this molecule
pan1 [cytosol]
pan1 [cytosol]
Inferred From
ITSN2 [cytosol]
(Homo sapiens)
Cross References
RefSeq
XP_001713105.1
PRO
Q10172
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