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About
What is Reactome ?
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Digital Preservation
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RPA heterotrimer [nucleoplasm]
Stable Identifier
R-SPO-68462
Type
Complex
Species
Schizosaccharomyces pombe
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Schizosaccharomyces pombe)
Cell Cycle Checkpoints (Schizosaccharomyces pombe)
G2/M Checkpoints (Schizosaccharomyces pombe)
Activation of ATR in response to replication stress (Schizosaccharomyces pombe)
Recruitment of Rad17-RFC complex to DNA (Schizosaccharomyces pombe)
RPA complexed to ssDNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Rad17-RFC complex bound to DNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA complexed to ssDNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Recruitment of the Rad9-Hus1-Rad1 complex to DNA (Schizosaccharomyces pombe)
Rad17-RFC complex bound to DNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA complexed to ssDNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Rad9-Hus1-Rad1 bound to DNA [nucleoplasm] (Schizosaccharomyces pombe)
Rad17-RFC complex bound to DNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA complexed to ssDNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Stalling of DNA replication fork and RPA binding (Schizosaccharomyces pombe)
RPA complexed to ssDNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Cell Cycle, Mitotic (Schizosaccharomyces pombe)
S Phase (Schizosaccharomyces pombe)
Synthesis of DNA (Schizosaccharomyces pombe)
DNA strand elongation (Schizosaccharomyces pombe)
Lagging Strand Synthesis (Schizosaccharomyces pombe)
Processive synthesis on the lagging strand (Schizosaccharomyces pombe)
Removal of the Flap Intermediate (Schizosaccharomyces pombe)
RPA binds to the Flap (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Recruitment of Dna2 endonuclease (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Removal of RNA primer and dissociation of RPA and Dna2 (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Chromosome Maintenance (Schizosaccharomyces pombe)
Telomere Maintenance (Schizosaccharomyces pombe)
Extension of Telomeres (Schizosaccharomyces pombe)
Telomere C-strand (Lagging Strand) Synthesis (Schizosaccharomyces pombe)
Processive synthesis on the C-strand of the telomere (Schizosaccharomyces pombe)
Removal of the Flap Intermediate from the C-strand (Schizosaccharomyces pombe)
Recruitment of DNA2 endonuclease to the C strand (Schizosaccharomyces pombe)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Cellular responses to stimuli (Schizosaccharomyces pombe)
Cellular responses to stress (Schizosaccharomyces pombe)
Cellular response to heat stress (Schizosaccharomyces pombe)
Regulation of HSF1-mediated heat shock response (Schizosaccharomyces pombe)
RPA1 binds HSF1 (Schizosaccharomyces pombe)
HSF1:RPA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
DNA Repair (Schizosaccharomyces pombe)
Base Excision Repair (Schizosaccharomyces pombe)
Resolution of Abasic Sites (AP sites) (Schizosaccharomyces pombe)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Schizosaccharomyces pombe)
PCNA-Dependent Long Patch Base Excision Repair (Schizosaccharomyces pombe)
LIG1 binds APEX1 and PCNA at SSB (Schizosaccharomyces pombe)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
LIG1 bound to APEX1 and PCNA ligates SSB (Schizosaccharomyces pombe)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
POLD,POLE-mediated DNA strand displacement synthesis (Schizosaccharomyces pombe)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
DNA Damage Bypass (Schizosaccharomyces pombe)
Recognition of DNA damage by PCNA-containing replication complex (Schizosaccharomyces pombe)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
USP1:WDR48 binds monoUb:K164-PCNA (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
USP1:WDR48 deubiquitinates monoUb:K164-PCNA (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:USP1:WDR48:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Schizosaccharomyces pombe)
Termination of translesion DNA synthesis (Schizosaccharomyces pombe)
POLD,POLE binds deISGylated PCNA after TLS (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Schizosaccharomyces pombe)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA (Schizosaccharomyces pombe)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Translesion Synthesis by POLH (Schizosaccharomyces pombe)
Elongation by POLH (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Insertion of correct bases opposite the lesion by POLH (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Schizosaccharomyces pombe)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Schizosaccharomyces pombe)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
NPLOC4:UFD1L:VPC:SPRTN:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-Template DNA [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Translesion synthesis by POLI (Schizosaccharomyces pombe)
POLI incorporates dNMP opposite to damaged DNA base (Schizosaccharomyces pombe)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:EtAD-DNA Template,Gamma-HOPdG-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
POLZ elongates POLI-incorporated dNMP (Schizosaccharomyces pombe)
POLI:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T-mispaireddNMPs)-DNA Template,(Gamma-HOPdG:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
POLI:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:(EtAD:T)-DNA Template,(Gamma-HOPdG:C)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Translesion synthesis by POLK (Schizosaccharomyces pombe)
POLK and POLZ cooperate in elongation of mispaired primer termini (Schizosaccharomyces pombe)
POLK:MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A-mispaireddNMPs)-DNA Template,(OGUA:A-mispaireddNMPs)-DNA Template,(BPDE-G:C-mispaireddNMPs)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
POLK forms a quaternary complex with REV1 and POLZ on damaged DNA template (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
POLK incorporates dNMP opposite to damaged DNA base (Schizosaccharomyces pombe)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:(Tg:A)-DNA Template,(OGUA:A)-DNA Template,(BPDE-G:C)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
POLK:REV1:POLZ:MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:Tg-DNA Template,OGUA-DNA Template,BPDE-G-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Translesion synthesis by REV1 (Schizosaccharomyces pombe)
POLZ extends translesion synthesis (Schizosaccharomyces pombe)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt-mispairedPolydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
REV1 binds AP-dsDNA (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
REV1 inserts dCMP opposite to AP sites in DNA (Schizosaccharomyces pombe)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
REV1:MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:AP-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
REV1 recruits POLZ to (AP:Cyt)-DNA Template (Schizosaccharomyces pombe)
POLZ:REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
REV1:MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:(AP:Cyt)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Mismatch Repair (Schizosaccharomyces pombe)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta) (Schizosaccharomyces pombe)
DNA polymerase delta polymerizes DNA across single stranded gap (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA:DNA containing single strand gap [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (Schizosaccharomyces pombe)
DNA polymerase delta polymerizes DNA across single stranded gap (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA:DNA containing single strand gap [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA:DNA containing single strand gap [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Nucleotide Excision Repair (Schizosaccharomyces pombe)
Global Genome Nucleotide Excision Repair (GG-NER) (Schizosaccharomyces pombe)
Dual Incision in GG-NER (Schizosaccharomyces pombe)
5'- incision of DNA by ERCC1:ERCC4 in GG-NER (Schizosaccharomyces pombe)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Schizosaccharomyces pombe)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Formation of Incision Complex in GG-NER (Schizosaccharomyces pombe)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in GG-NER (Schizosaccharomyces pombe)
GG-NER incision complex:Open bubble dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Formation of the pre-incision complex in GG-NER (Schizosaccharomyces pombe)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Gap-filling DNA repair synthesis and ligation in GG-NER (Schizosaccharomyces pombe)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Schizosaccharomyces pombe)
Dual incision in TC-NER (Schizosaccharomyces pombe)
3' incision by ERCC5 (XPG) in TC-NER (Schizosaccharomyces pombe)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Schizosaccharomyces pombe)
TC-NER incision complex [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Schizosaccharomyces pombe)
TC-NER incision complex [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Schizosaccharomyces pombe)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
ERCC5 and RPA bind TC-NER site (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Gap-filling DNA repair synthesis and ligation in TC-NER (Schizosaccharomyces pombe)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Schizosaccharomyces pombe)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
DNA Replication (Schizosaccharomyces pombe)
Synthesis of DNA (Schizosaccharomyces pombe)
DNA strand elongation (Schizosaccharomyces pombe)
Lagging Strand Synthesis (Schizosaccharomyces pombe)
Processive synthesis on the lagging strand (Schizosaccharomyces pombe)
Removal of the Flap Intermediate (Schizosaccharomyces pombe)
RPA binds to the Flap (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Recruitment of Dna2 endonuclease (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Removal of RNA primer and dissociation of RPA and Dna2 (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
ssb1 [nucleoplasm]
(Schizosaccharomyces pombe)
ssb2 [nucleoplasm]
(Schizosaccharomyces pombe)
ssb3 [nucleoplasm]
(Schizosaccharomyces pombe)
Participates
as a component of
PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
HSF1:RPA [nucleoplasm] (Schizosaccharomyces pombe)
RPA:DNA containing single strand gap [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
GG-NER pre-incision complex:Open bubble-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
GG-NER incision complex:5'-incised damaged DNA [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RPA complexed to ssDNA [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
MonoUb:K164-PCNA:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
as an input of
RPA1 binds HSF1 (Schizosaccharomyces pombe)
EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Schizosaccharomyces pombe)
ERCC5 and RPA bind TC-NER site (Schizosaccharomyces pombe)
Formation of the pre-incision complex in GG-NER (Schizosaccharomyces pombe)
RPA binds to the Flap (Schizosaccharomyces pombe)
Stalling of DNA replication fork and RPA binding (Schizosaccharomyces pombe)
as an output of
DNA polymerase delta polymerizes DNA across single stranded gap (Schizosaccharomyces pombe)
Removal of RNA primer and dissociation of RPA and Dna2 (Schizosaccharomyces pombe)
Inferred From
RPA heterotrimer [nucleoplasm]
(Homo sapiens)
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