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About
What is Reactome ?
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Digital Preservation
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PCNA homotrimer [nucleoplasm]
Stable Identifier
R-SPO-68440
Type
Complex
Species
Schizosaccharomyces pombe
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Cell Cycle (Schizosaccharomyces pombe)
Cell Cycle, Mitotic (Schizosaccharomyces pombe)
S Phase (Schizosaccharomyces pombe)
Synthesis of DNA (Schizosaccharomyces pombe)
DNA strand elongation (Schizosaccharomyces pombe)
Lagging Strand Synthesis (Schizosaccharomyces pombe)
Polymerase switching (Schizosaccharomyces pombe)
Formation of Processive Complex (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Loading of PCNA - Sliding Clamp Formation (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RFC dissociates after sliding clamp formation (Schizosaccharomyces pombe)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive synthesis on the lagging strand (Schizosaccharomyces pombe)
Formation of Okazaki fragments (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Formation of the Flap Intermediate (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Removal of the Flap Intermediate (Schizosaccharomyces pombe)
RPA binds to the Flap (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Recruitment of Dna2 endonuclease (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Removal of RNA primer and dissociation of RPA and Dna2 (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Removal of remaining Flap (Schizosaccharomyces pombe)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Leading Strand Synthesis (Schizosaccharomyces pombe)
Polymerase switching (Schizosaccharomyces pombe)
Formation of Processive Complex (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Loading of PCNA - Sliding Clamp Formation (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RFC dissociates after sliding clamp formation (Schizosaccharomyces pombe)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Chromosome Maintenance (Schizosaccharomyces pombe)
Telomere Maintenance (Schizosaccharomyces pombe)
Extension of Telomeres (Schizosaccharomyces pombe)
Telomere C-strand (Lagging Strand) Synthesis (Schizosaccharomyces pombe)
Processive synthesis on the C-strand of the telomere (Schizosaccharomyces pombe)
Removal of the Flap Intermediate from the C-strand (Schizosaccharomyces pombe)
Recruitment of DNA2 endonuclease to the C strand (Schizosaccharomyces pombe)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
DNA Repair (Schizosaccharomyces pombe)
Base Excision Repair (Schizosaccharomyces pombe)
Resolution of Abasic Sites (AP sites) (Schizosaccharomyces pombe)
Resolution of AP sites via the multiple-nucleotide patch replacement pathway (Schizosaccharomyces pombe)
PCNA-Dependent Long Patch Base Excision Repair (Schizosaccharomyces pombe)
LIG1 binds APEX1 and PCNA at SSB (Schizosaccharomyces pombe)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
LIG1 bound to APEX1 and PCNA ligates SSB (Schizosaccharomyces pombe)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:SSB:(3'poly-dNMP)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
APEX1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
LIG1:APEX1:PCNA:POLD,POLE:RPA:RFC:dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
POLD,POLE-mediated DNA strand displacement synthesis (Schizosaccharomyces pombe)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'dNMP-displaced 5'ddRP)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
APEX1:FEN1:PCNA:POLD,POLE:RPA:RFC:SSB(3'poly-dNMP-displaced 5'ddRP flap)-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
DNA Damage Bypass (Schizosaccharomyces pombe)
Recognition of DNA damage by PCNA-containing replication complex (Schizosaccharomyces pombe)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL monoubiquitinates PCNA (Schizosaccharomyces pombe)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RAD18:UBE2B or RBX1:CUL4:DDB1:DTL ubiquitin ligase complex binds PCNA:POLD,POLE:RPA:RFC associated with damaged dsDNA (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RAD18:UBE2B,RBX1:CUL4:DDB1:DTL:PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
USP1:WDR48 deubiquitinates monoUb:K164-PCNA (Schizosaccharomyces pombe)
PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Schizosaccharomyces pombe)
Termination of translesion DNA synthesis (Schizosaccharomyces pombe)
POLD,POLE binds deISGylated PCNA after TLS (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Mismatch Repair (Schizosaccharomyces pombe)
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha) (Schizosaccharomyces pombe)
EXO1 interacting with MSH2:MSH6 excises single strand DNA containing a mismatch (Schizosaccharomyces pombe)
EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
EXO1 interacts with MSH2:MSH6 (MutSalpha) and MLH1:PMS2 (MutLalpha) (Schizosaccharomyces pombe)
EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2 makes single strand incision near 1-2 base mismatch (Schizosaccharomyces pombe)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Schizosaccharomyces pombe)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Nucleotide Excision Repair (Schizosaccharomyces pombe)
Global Genome Nucleotide Excision Repair (GG-NER) (Schizosaccharomyces pombe)
Dual Incision in GG-NER (Schizosaccharomyces pombe)
DNA polymerases delta, epsilon or kappa bind the GG-NER site (Schizosaccharomyces pombe)
GG-NER incision complex:5'-incised damaged DNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer,MonoUb:K164-PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Gap-filling DNA repair synthesis and ligation in GG-NER (Schizosaccharomyces pombe)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in GG-NER (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:Incised DNA without lesion [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC:SSB-dsDNA [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Schizosaccharomyces pombe)
Dual incision in TC-NER (Schizosaccharomyces pombe)
3' incision by ERCC5 (XPG) in TC-NER (Schizosaccharomyces pombe)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Schizosaccharomyces pombe)
PCNA homotrimer,MonoUb:K164-PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Gap-filling DNA repair synthesis and ligation in TC-NER (Schizosaccharomyces pombe)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Schizosaccharomyces pombe)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK) [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
DNA Replication (Schizosaccharomyces pombe)
Synthesis of DNA (Schizosaccharomyces pombe)
DNA strand elongation (Schizosaccharomyces pombe)
Lagging Strand Synthesis (Schizosaccharomyces pombe)
Polymerase switching (Schizosaccharomyces pombe)
Formation of Processive Complex (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Loading of PCNA - Sliding Clamp Formation (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RFC dissociates after sliding clamp formation (Schizosaccharomyces pombe)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive synthesis on the lagging strand (Schizosaccharomyces pombe)
Formation of Okazaki fragments (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Formation of the Flap Intermediate (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Removal of the Flap Intermediate (Schizosaccharomyces pombe)
RPA binds to the Flap (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Recruitment of Dna2 endonuclease (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Removal of RNA primer and dissociation of RPA and Dna2 (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer:dna2 [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragment complex [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Removal of remaining Flap (Schizosaccharomyces pombe)
Processive complex:Okazaki fragments:Remaining Flap [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex:nicked DNA from adjacent Okazaki fragments [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Leading Strand Synthesis (Schizosaccharomyces pombe)
Polymerase switching (Schizosaccharomyces pombe)
Formation of Processive Complex (Schizosaccharomyces pombe)
Processive complex [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Loading of PCNA - Sliding Clamp Formation (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RFC dissociates after sliding clamp formation (Schizosaccharomyces pombe)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 3
pcn1 [nucleoplasm]
(Schizosaccharomyces pombe)
Participates
as a component of
PCNA:RPA:RFC:Damaged DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch [nucleoplasm] (Schizosaccharomyces pombe)
MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Schizosaccharomyces pombe)
EXO1:MLH1:PMS2:MSH2:MSH6:ATP:PCNA:DNA containing 1-2 base mismatch and single strand incision [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE [nucleoplasm] (Schizosaccharomyces pombe)
RFC Heteropentamer:RNA primer-DNA primer:origin duplex:PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
RNA primer-DNA primer:origin duplex:PCNA [nucleoplasm] (Schizosaccharomyces pombe)
RFC Heteropentamer:RNA primer-DNA primer:G-strand extended telomere end duplex:PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
PCNA:POLD,POLE:RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
as an input of
MSH2:MSH6 recruits MLH1:PMS2 to mismatch and interacts with PCNA (Schizosaccharomyces pombe)
Loading of PCNA - Sliding Clamp Formation (Schizosaccharomyces pombe)
as a member of
PCNA homotrimer,MonoUb:K164-PCNA homotrimer [nucleoplasm] (Schizosaccharomyces pombe)
Inferred From
PCNA homotrimer [nucleoplasm]
(Homo sapiens)
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