Reactome | lsc1 [nucleoplasm]

lsc1 [nucleoplasm]

Stable Identifier

R-SPO-6796619

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

nucleoplasm

Synonyms

CCNK, O59748

Locations in the PathwayBrowser

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Gene expression (Transcription) (Schizosaccharomyces pombe)

- RNA Polymerase II Transcription (Schizosaccharomyces pombe)
  - Generic Transcription Pathway (Schizosaccharomyces pombe)
    - Transcriptional Regulation by TP53 (Schizosaccharomyces pombe)
      - TP53 Regulates Transcription of DNA Repair Genes (Schizosaccharomyces pombe)
        
        CCNK binds CDK12 (Schizosaccharomyces pombe)
        
        CCNK:CDK12 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        CCNK binds CDK13 (Schizosaccharomyces pombe)
        
        CCNK:CDK13 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        CCNK:CDK12 binds RNA Pol II at DNA repair genes (Schizosaccharomyces pombe)
        
        CCNK:CDK12 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Schizosaccharomyces pombe)
        
        CCNK:CDK12 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Elongation Complex at DNA Repair Genes [nucleoplasm] (Schizosaccharomyces pombe)
        
        Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Schizosaccharomyces pombe)
        
        P-TEFb complex [nucleoplasm] (Schizosaccharomyces pombe)
        
        CCNT1,CCNT2,CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Elongation Complex at DNA Repair Genes [nucleoplasm] (Schizosaccharomyces pombe)
        
        Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Schizosaccharomyces pombe)
        
        P-TEFb complex [nucleoplasm] (Schizosaccharomyces pombe)
        
        CCNT1,CCNT2,CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        CDK12 phosphorylates RNA Pol II CTD at DNA repair genes (Schizosaccharomyces pombe)
        
        CCNK:CDK12 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        CCNK:CDK12:CDK12-Phosphorylated Elongation Complex at DNA repair genes [nucleoplasm] (Schizosaccharomyces pombe)
        
        CCNK:CDK12 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        CDK12-Phosphorylated Elongation Complex [nucleoplasm] (Schizosaccharomyces pombe)
        
        CDK12-phosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Schizosaccharomyces pombe)
        
        P-TEFb complex [nucleoplasm] (Schizosaccharomyces pombe)
        
        CCNT1,CCNT2,CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        CCNK:CDK12:Elongation Complex at DNA Repair Genes [nucleoplasm] (Schizosaccharomyces pombe)
        
        CCNK:CDK12 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Elongation Complex at DNA Repair Genes [nucleoplasm] (Schizosaccharomyces pombe)
        
        Hyperphosphorylated RNA Pol II at DNA repair genes [nucleoplasm] (Schizosaccharomyces pombe)
        
        P-TEFb complex [nucleoplasm] (Schizosaccharomyces pombe)
        
        CCNT1,CCNT2,CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
  - RNA Polymerase II Pre-transcription Events (Schizosaccharomyces pombe)
    - Formation of P-TEFb complex (Schizosaccharomyces pombe)
      - CCNT1,CCNT2,CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
      - P-TEFb complex [nucleoplasm] (Schizosaccharomyces pombe)
        
        CCNT1,CCNT2,CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
  - RNA polymerase II transcribes snRNA genes (Schizosaccharomyces pombe)
    - CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Schizosaccharomyces pombe)
      - RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Schizosaccharomyces pombe)
        
        Initiation factors:CDK7:snRNA gene [nucleoplasm] (Schizosaccharomyces pombe)
        
        P-TEFb complex [nucleoplasm] (Schizosaccharomyces pombe)
        
        CCNT1,CCNT2,CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)
      - RNA polymerase II (unphosphorylated):Initiation factors at promoter of snRNA gene [nucleoplasm] (Schizosaccharomyces pombe)
        
        RNA polymerase II (unphosphorylated):Initiation factors [nucleoplasm] (Schizosaccharomyces pombe)
        
        P-TEFb complex [nucleoplasm] (Schizosaccharomyces pombe)
        
        CCNT1,CCNT2,CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)
        
        lsc1 [nucleoplasm] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:O59748

Gene Names

lsc1

Reference Genes

ENSEMBL:SPBC530.13

PomBase:SPBC530.13

UCSC:O59748 lsc1

Participates

as a member of

Homologues of CCNK [nucleoplasm] (Schizosaccharomyces pombe)

Other forms of this molecule

lsc1 [nucleoplasm]

Inferred From

CCNK [nucleoplasm] (Homo sapiens)

Cross References

PRO

O59748

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