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TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm]
Stable Identifier
R-SPO-6782111
Type
Complex
Species
Schizosaccharomyces pombe
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Repair (Schizosaccharomyces pombe)
Nucleotide Excision Repair (Schizosaccharomyces pombe)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Schizosaccharomyces pombe)
Dual incision in TC-NER (Schizosaccharomyces pombe)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Schizosaccharomyces pombe)
TC-NER incision complex [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Schizosaccharomyces pombe)
TC-NER incision complex [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
ERCC5 and RPA bind TC-NER site (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
TCEA1 [nucleoplasm]
(Schizosaccharomyces pombe)
Ubiquitinated,hyperphosphorylated RNA Pol II:Open bubble damaged DNA template:nascent mRNA hybrid:TFIIH:ERCC6:ERCC8:DDB1:CUL4:RBX1 [nucleoplasm]
(Schizosaccharomyces pombe)
UVSSA:USP7 [nucleoplasm]
(Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm]
(Schizosaccharomyces pombe)
XPA [nucleoplasm]
(Schizosaccharomyces pombe)
Participates
as an output of
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Schizosaccharomyces pombe)
as an input of
ERCC5 and RPA bind TC-NER site (Schizosaccharomyces pombe)
as a component of
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
Inferred From
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm]
(Homo sapiens)
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