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XAB2 complex [nucleoplasm]
Stable Identifier
R-SPO-6781957
Type
Complex
Species
Schizosaccharomyces pombe
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
DNA Repair (Schizosaccharomyces pombe)
Nucleotide Excision Repair (Schizosaccharomyces pombe)
Transcription-Coupled Nucleotide Excision Repair (TC-NER) (Schizosaccharomyces pombe)
Dual incision in TC-NER (Schizosaccharomyces pombe)
3' incision by ERCC5 (XPG) in TC-NER (Schizosaccharomyces pombe)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
5' incision of damaged DNA strand by ERCC1:ERCC4 in TC-NER (Schizosaccharomyces pombe)
TC-NER incision complex [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
Binding of ERCC1:ERCC4 (ERCC1:XPF) to pre-incision complex in TC-NER (Schizosaccharomyces pombe)
TC-NER incision complex [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerases delta, epsilon or kappa bind the TC-NER site (Schizosaccharomyces pombe)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
ERCC2-facilitated RNA Pol II backtracking in TC-NER (Schizosaccharomyces pombe)
TC-NER pre-incision complex [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
ERCC3-facilitated RNA Pol II backtracking in TC-NER (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
ERCC5 and RPA bind TC-NER site (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:RPA:ERCC5:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
Formation of TC-NER Pre-Incision Complex (Schizosaccharomyces pombe)
UVSSA:USP7 deubiquitinates ERCC6 (Schizosaccharomyces pombe)
TC-NER pre-incision complex [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
Gap-filling DNA repair synthesis and ligation in TC-NER (Schizosaccharomyces pombe)
Ligation of newly synthesized repair patch to incised DNA in TC-NER (Schizosaccharomyces pombe)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
Repair DNA synthesis of ~27-30 bases long patch by POLD, POLE or POLK in TC-NER (Schizosaccharomyces pombe)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
XAB2 complex [nucleoplasm] (Schizosaccharomyces pombe)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
cwf12 [nucleoplasm]
(Schizosaccharomyces pombe)
cwf3 [nucleoplasm]
(Schizosaccharomyces pombe)
Ghost homologue of AQR [nucleoplasm]
(Schizosaccharomyces pombe)
Ghost homologue of PPIE [nucleoplasm]
(Schizosaccharomyces pombe)
Ghost homologue of ZNF830 [nucleoplasm]
(Schizosaccharomyces pombe)
prp19 [nucleoplasm]
(Schizosaccharomyces pombe)
Participates
as a component of
TC-NER post-incision complex:dsDNA with transcription bubble [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER post-incision complex:SSB-dsDNA:trimmed nascent mRNA: (PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER post-incision complex:incised DNA without lesion:trimmed nascent mRNA:PCNA:(PCNA:POLD,POLE),(MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER incision complex: 5'-incised damaged DNA:trimmed nascent mRNA:(PCNA:POLD,POLE), (MonoUb:K164-PCNA:POLK):RPA:RFC [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER incision complex:5'-incised damaged DNA:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex:Partially open bubble damaged DNA template:trimmed nascent mRNA [nucleoplasm] (Schizosaccharomyces pombe)
TC-NER pre-incision complex [nucleoplasm] (Schizosaccharomyces pombe)
Ubiquitinated,hyperphosphorylated RNA Pol II:Damaged DNA template:nascent mRNA hybrid:TFIIH:Ub:ERCC6:ERCC8:DDB1:CUL4:RBX1:UVSSA:USP7:XAB2 complex:XPA:TCEA1:HMGN1:EP300 [nucleoplasm] (Schizosaccharomyces pombe)
Inferred From
XAB2 complex [nucleoplasm]
(Homo sapiens)
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