Reactome | phospho-cnp1 [nucleoplasm]

phospho-cnp1 [nucleoplasm]

Stable Identifier

R-SPO-5625859

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

nucleoplasm

Synonyms

p-T12,MeK-10-HIST1H3A, Q9Y812

Locations in the PathwayBrowser

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Signal Transduction (Schizosaccharomyces pombe)

- Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Schizosaccharomyces pombe)
  - Signaling by Rho GTPases (Schizosaccharomyces pombe)
    - RHO GTPase Effectors (Schizosaccharomyces pombe)
      - RHO GTPases activate PKNs (Schizosaccharomyces pombe)
        
        Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Schizosaccharomyces pombe)
        
        KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Schizosaccharomyces pombe)
        
        p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T12,MeK-10-H3 [nucleoplasm] (Schizosaccharomyces pombe)
        
        phospho-cnp1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Schizosaccharomyces pombe)
        
        p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Schizosaccharomyces pombe)
        
        p-T12,MeK-10-H3 [nucleoplasm] (Schizosaccharomyces pombe)
        
        phospho-cnp1 [nucleoplasm] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:Q9Y812

Gene Names

cnp1

Reference Genes

BioGPS Gene:2539658 cnp1

ENSEMBL:SPBC1105.17

KEGG Gene (Schizosaccharomyces pombe):SPBC1105.17 cnp1

Monarch:2539658 cnp1

NCBI Gene:2539658 cnp1

PomBase:SPBC1105.17

Reference Transcript

RefSeq:NM_001022392.2 cnp1

Participates

as a member of

p-T12,MeK-10-H3 [nucleoplasm] (Schizosaccharomyces pombe)

Other forms of this molecule

cnp1 [nucleoplasm]

cnp1 [cytosol]

cnp1 [nucleoplasm]

phospho-cnp1 [nucleoplasm]

cnp1 [nucleoplasm]

Inferred From

p-T12,MeK-10-HIST1H3A [nucleoplasm] (Homo sapiens)

p-T12,MeK-HIST2H3A [nucleoplasm] (Homo sapiens)

Modified Residues

Name

N6-methyl-L-lysine at 10 (in Homo sapiens)

Coordinate

PsiMod Name

N6-methyl-L-lysine [MOD:00085]

PsiMod Definition

A protein modification that effectively converts an L-lysine residue to N6-methyl-L-lysine.

Name

O-phospho-L-threonine at 12 (in Homo sapiens)

Coordinate

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_596473.1

PRO

Q9Y812

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9Y738 MIS12			0.528	3