Reactome | GGT5(1-387) [plasma membrane]

GGT5(1-387) [plasma membrane]

Stable Identifier

R-SPO-265313

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

plasma membrane

Synonyms

O14194

Locations in the PathwayBrowser

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Metabolism (Schizosaccharomyces pombe)

- Biological oxidations (Schizosaccharomyces pombe)
  - Aflatoxin activation and detoxification (Schizosaccharomyces pombe)
    - GGTs hydrolyse glutamate from AFXBO-SG, AFNBO-SG (Schizosaccharomyces pombe)
      - GGT dimers [plasma membrane] (Schizosaccharomyces pombe)
        
        GGT5 dimer [plasma membrane] (Schizosaccharomyces pombe)
        
        Homologues of GGT5(1-387) [plasma membrane] (Schizosaccharomyces pombe)
        
        GGT5(1-387) [plasma membrane] (Schizosaccharomyces pombe)
  - Phase II - Conjugation of compounds (Schizosaccharomyces pombe)
    - Glutathione conjugation (Schizosaccharomyces pombe)
      - Glutathione synthesis and recycling (Schizosaccharomyces pombe)
        
        GGT dimers hydrolyse GSH (Schizosaccharomyces pombe)
        
        GGT dimers [plasma membrane] (Schizosaccharomyces pombe)
        
        GGT5 dimer [plasma membrane] (Schizosaccharomyces pombe)
        
        Homologues of GGT5(1-387) [plasma membrane] (Schizosaccharomyces pombe)
        
        GGT5(1-387) [plasma membrane] (Schizosaccharomyces pombe)
- Metabolism of lipids (Schizosaccharomyces pombe)
  - Fatty acid metabolism (Schizosaccharomyces pombe)
    - Arachidonic acid metabolism (Schizosaccharomyces pombe)
      - Synthesis of Leukotrienes (LT) and Eoxins (EX) (Schizosaccharomyces pombe)
        
        GGT1, 5 dimers hydrolyse LTC4 to LTD4 (Schizosaccharomyces pombe)
        
        GGT1, 5 dimers [plasma membrane] (Schizosaccharomyces pombe)
        
        GGT5 dimer [plasma membrane] (Schizosaccharomyces pombe)
        
        Homologues of GGT5(1-387) [plasma membrane] (Schizosaccharomyces pombe)
        
        GGT5(1-387) [plasma membrane] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:O14194

Reference Genes

BioGPS Gene:2543110

ENSEMBL:SPAC56E4.06c

GeneDB:SPAC56E4.06c

KEGG Gene (Schizosaccharomyces pombe):SPAC56E4.06c

Monarch:2543110

NCBI Gene:2543110

Reference Transcript

RefSeq:NM_001018670.2

Participates

as a member of

Homologues of GGT5(1-387) [plasma membrane] (Schizosaccharomyces pombe)

Other forms of this molecule

GGT1(381-569) [plasma membrane]

GGT7(473-662) [plasma membrane]

GGT7(1-472) [plasma membrane]

GGT1(1-380) [plasma membrane]

GGT3P(381-568) [plasma membrane]

GGT5(388-586) [plasma membrane]

Inferred From

GGT5(1-387) [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_593273.1

PRO

O14194

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