Reactome | pot1 [nucleoplasm]

pot1 [nucleoplasm]

Stable Identifier

R-SPO-174890

Type

Protein [EntityWithAccessionedSequence]

Species

Schizosaccharomyces pombe

Compartment

nucleoplasm

Synonyms

POT1, O13988

Locations in the PathwayBrowser

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Cell Cycle (Schizosaccharomyces pombe)

- Chromosome Maintenance (Schizosaccharomyces pombe)
  - Telomere Maintenance (Schizosaccharomyces pombe)
    - Extension of Telomeres (Schizosaccharomyces pombe)
      - Telomere C-strand (Lagging Strand) Synthesis (Schizosaccharomyces pombe)
        
        Processive synthesis on the C-strand of the telomere (Schizosaccharomyces pombe)
        
        Removal of the Flap Intermediate from the C-strand (Schizosaccharomyces pombe)
        
        Recruitment of DNA2 endonuclease to the C strand (Schizosaccharomyces pombe)
        
        Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
        
        Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
        
        Shelterin complex [nucleoplasm] (Schizosaccharomyces pombe)
        
        pot1 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer:DNA2 [nucleoplasm] (Schizosaccharomyces pombe)
        
        Processive complex loaded on telomere:Okazaki fragment:Flap:RPA heterotrimer [nucleoplasm] (Schizosaccharomyces pombe)
        
        Processive complex loaded on telomere:Okazaki fragment:Flap [nucleoplasm] (Schizosaccharomyces pombe)
        
        Shelterin complex [nucleoplasm] (Schizosaccharomyces pombe)
        
        pot1 [nucleoplasm] (Schizosaccharomyces pombe)

External Reference Information

External Reference

UniProt:O13988

Gene Names

pot1

Reference Genes

BioGPS Gene:2542703 pot1

ENSEMBL:SPAC26H5.06

GeneDB:SPAC26H5.06

KEGG Gene (Schizosaccharomyces pombe):SPAC26H5.06 pot1

Monarch:2542703 pot1

NCBI Gene:2542703 pot1

Reference Transcript

RefSeq:NM_001019882.2 pot1

Participates

as a component of

Shelterin complex [nucleoplasm] (Schizosaccharomyces pombe)

Inferred From

POT1 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_594453.1

PRO

O13988

PDB

6BWY, 5USO, 5USN, 4HID, 7CUH, 4HJ8, 1QZH, 4HJ5, 7CUI, 4HIK, 4HJA, 4HJ9, 1QZG, 4HIM, 5USB, 4HIO, 4HJ7

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