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set2 [nucleoplasm]
Stable Identifier
R-SPO-1183215
Type
Protein [EntityWithAccessionedSequence]
Species
Schizosaccharomyces pombe
Compartment
nucleoplasm
Synonyms
WHSC1, O14026
Locations in the PathwayBrowser
Expand all
Chromatin organization (Schizosaccharomyces pombe)
Chromatin modifying enzymes (Schizosaccharomyces pombe)
PKMTs methylate histone lysines (Schizosaccharomyces pombe)
WHSC1 (KMT3G) methylates lysine-28 of histone H3 (H3K27) (Schizosaccharomyces pombe)
set2 [nucleoplasm] (Schizosaccharomyces pombe)
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C) methylate lysine-37 of histone H3 (H3K36) (Schizosaccharomyces pombe)
WHSC1, NSD1, SMYD2, ASH1L [nucleoplasm] (Schizosaccharomyces pombe)
set2 [nucleoplasm] (Schizosaccharomyces pombe)
WHSC1 (KMT3G), NSD1 (KMT3B), SMYD2 (KMT3C), ASH1L methylate methyl-lysine-37 of histone H3 (H3K36) (Schizosaccharomyces pombe)
WHSC1, NSD1, SMYD2, ASH1L [nucleoplasm] (Schizosaccharomyces pombe)
set2 [nucleoplasm] (Schizosaccharomyces pombe)
WHSC1L1 (KMT3F) methylates dimethyl-lysine-28 of histone H3 (H3K27) (Schizosaccharomyces pombe)
set2 [nucleoplasm] (Schizosaccharomyces pombe)
WHSC1L1 (KMT3F) methylates methyl-lysine-28 of histone H3 (H3K27) (Schizosaccharomyces pombe)
set2 [nucleoplasm] (Schizosaccharomyces pombe)
DNA Repair (Schizosaccharomyces pombe)
DNA Double-Strand Break Repair (Schizosaccharomyces pombe)
DNA Double Strand Break Response (Schizosaccharomyces pombe)
Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks (Schizosaccharomyces pombe)
ATM phosphorylates WHSC1 (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
set2 [nucleoplasm] (Schizosaccharomyces pombe)
WHSC1 binds DNA DSBs (Schizosaccharomyces pombe)
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
set2 [nucleoplasm] (Schizosaccharomyces pombe)
set2 [nucleoplasm] (Schizosaccharomyces pombe)
WHSC1 dimethylates histone H4 on lysine K21 at DSBs (Schizosaccharomyces pombe)
set2 [nucleoplasm] (Schizosaccharomyces pombe)
External Reference Information
External Reference
UniProt:O14026
Gene Names
set2
Reference Genes
BioGPS Gene:2542070 set2
ENSEMBL:SPAC29B12.02c
KEGG Gene (Schizosaccharomyces pombe):SPAC29B12.02c set2
Monarch:2542070 set2
NCBI Gene:2542070 set2
PomBase:SPAC29B12.02c
Reference Transcript
RefSeq:NM_001020411.2 set2
Participates
as a member of
WHSC1, NSD1, SMYD2, ASH1L [nucleoplasm] (Schizosaccharomyces pombe)
as an input of
WHSC1 binds DNA DSBs (Schizosaccharomyces pombe)
as a component of
DNA DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:p-S139-H2AFX-Nucleosome:p-5T-MDC1:WHSC1 [nucleoplasm] (Schizosaccharomyces pombe)
Other forms of this molecule
set2 [nucleoplasm]
set2 [nucleoplasm]
phospho-set2 [nucleoplasm]
Inferred From
WHSC1, WHSC1L1 [nucleoplasm]
(Homo sapiens)
WHSC1 [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_594980.1
IntEnz
2.1.1.359
PRO
O14026
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