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POLH [nucleoplasm]
Stable Identifier
R-SPO-110287
Type
Protein [EntityWithAccessionedSequence]
Species
Schizosaccharomyces pombe
Compartment
nucleoplasm
Synonyms
O42917
Locations in the PathwayBrowser
Expand all
DNA Repair (Schizosaccharomyces pombe)
DNA Damage Bypass (Schizosaccharomyces pombe)
Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template (Schizosaccharomyces pombe)
Termination of translesion DNA synthesis (Schizosaccharomyces pombe)
USP10 binds monoUb:K164,ISG:K164,ISG:K168-PCNA (Schizosaccharomyces pombe)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase Y [nucleoplasm] (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase Y [nucleoplasm] (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
USP10 deubiquitinates monoUb:K164,ISG:K164,ISG:K168-PCNA (Schizosaccharomyces pombe)
DNA polymerase Y [nucleoplasm] (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
USP10:DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase Y:MonoUb:K164,ISG:K164,ISG:K168-PCNA:RPA:RFC:TLS-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
DNA polymerase Y [nucleoplasm] (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
Translesion Synthesis by POLH (Schizosaccharomyces pombe)
Elongation by POLH (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
Insertion of correct bases opposite the lesion by POLH (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
SPRTN recruits VCP to monoUb:K164-PCNA associated with POLH (Schizosaccharomyces pombe)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Schizosaccharomyces pombe)
NPLOC4:UFD1L:VCP:SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
SPRTN:POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
POLH [nucleoplasm] (Schizosaccharomyces pombe)
External Reference Information
External Reference
UniProt:O42917
Reference Genes
BioGPS Gene:2539666
ENSEMBL:SPBC16A3.11
KEGG:spo:2539666
Monarch:2539666
NCBI Gene:2539666
PomBase:SPBC16A3.11
UCSC:O42917
Reference Transcript
RefSeq:NM_001023799.2
Participates
as a member of
DNA polymerase Y [nucleoplasm] (Schizosaccharomyces pombe)
as an output of
SPRTN:VCP-mediated release of POLH from monoUb:K164-PCNA (Schizosaccharomyces pombe)
as an input of
POLH binds monoUb:K164-PCNA at damaged TT-CPD-DNA template (Schizosaccharomyces pombe)
as a component of
POLH:MonoUb:K164-PCNA:RPA:RFC:TT-CPD-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
POLH:MonoUb:K164-PCNA:RPA:RFC:(TT-CPD:AA-polydNMP)-DNA Template [nucleoplasm] (Schizosaccharomyces pombe)
Inferred From
POLH [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_596778.1
PRO
O42917
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