Reactome | yORC6 [nucleoplasm]

yORC6 [nucleoplasm]

Stable Identifier

R-SCE-9749321

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

Origin recognition complex subunit 6, ORC6_YEAST

External Reference Information

External Reference

UniProt:P38826 ORC6

Gene Names

ORC6, AAP1, YHR118C

Chain

chain:1-435

Reference Genes

BioGPS Gene:856518 ORC6

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YHR118C ORC6

Monarch:856518 ORC6

NCBI Gene:856518 ORC6

Reference Transcript

RefSeq:NM_001179248.1 ORC6

Other Identifiers

1770102_at

4411_at

856518

GO:0003674

GO:0003677

GO:0003688

GO:0005515

GO:0005575

GO:0005634

GO:0005654

GO:0005656

GO:0005664

GO:0005694

GO:0006260

GO:0006267

GO:0006270

GO:0006325

GO:0008150

GO:0030466

GO:0031261

Participates

as a component of

yORC(1-6) [nucleoplasm] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_011986.1

OpenTargets

ENSG00000091651

PRO

P38826

PDB

7TJI, 6RQC, 6WGC, 7TJJ, 7TJK, 7MCA, 6WGI, 5V8F, 6WGG, 5ZR1, 7TJH, 7TJF

Interactors (9)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P32833 ORC2	2	yORC2 [nucleoplasm] (R-SCE-9749316) ORC2 [nucleoplasm] (R-SCE-68405)	0.772	22
UniProt:P54784 ORC1	6	phospho-PolyUb,p-S,T-ORC1 [cytosol] (R-SCE-9032195) phospho-PolyUb,p-S,T-ORC1 [nucleoplasm] (R-SCE-9032189) phospho-p-S,T-ORC1 [nucleoplasm] (R-SCE-68943) ORC1 [cytosol] (R-SCE-113840) yORC1 [nucleoplasm] (R-SCE-9749323) ORC1 [nucleoplasm] (R-SCE-68522)	0.745	17
UniProt:P50874 ORC5	2	yORC5 [nucleoplasm] (R-SCE-9749322) ORC5 [nucleoplasm] (R-SCE-68516)	0.678	12
UniProt:P54790 ORC3	2	yORC3 [nucleoplasm] (R-SCE-9749325) ORC3 [nucleoplasm] (R-SCE-68513)	0.678	11
UniProt:P09119 CDC6	5	CDC6 [cytosol] (R-SCE-113566) phospho-p-CDC6 [cytosol] (R-SCE-68583) phospho-p-CDC6 [nucleoplasm] (R-SCE-5661317) yCDC6 [nucleoplasm] (R-SCE-9749328) CDC6 [nucleoplasm] (R-SCE-68542)	0.652	3
UniProt:P02309	14	HHF2 [nucleoplasm] (R-SCE-4570518) HHF2 [nucleoplasm] (R-SCE-212078) HHF2 [nucleoplasm] (R-SCE-4568744) HHF2 [nucleoplasm] (R-SCE-5229015) HHF2 [nucleoplasm] (R-SCE-4754243) HHF2 [nucleoplasm] (R-SCE-4754240) HHF2 [nucleoplasm] (R-SCE-5651656) HHF2 [nucleoplasm] (R-SCE-427469) HHF2 [nucleoplasm] (R-SCE-4568748) HHF2 [nucleoplasm] (R-SCE-4568758) HHF2 [nucleoplasm] (R-SCE-5423110) HHF2 [nucleoplasm] (R-SCE-3451124) HHF2 [nucleoplasm] (R-SCE-5651652) HHF2 [nucleoplasm] (R-SCE-181902)	0.564	2
UniProt:P54791 ORC4	2	yORC4 [nucleoplasm] (R-SCE-9749319) ORC4 [nucleoplasm] (R-SCE-68519)	0.564	15
UniProt:Q00684	3	CDC14 [cytosol] (R-SCE-174094) CDC14 [nucleoplasm] (R-SCE-5692694) CDC14 [nucleoplasm] (R-SCE-3214897)	0.558	2
UniProt:P10592	20	SSA2 [cytosol] (R-SCE-264476) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801512-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801496-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801494) SSA2 [extracellular region] (R-SCE-6805872-3) SSA2 [extracellular region] (R-SCE-6806500-3) SSA2 [extracellular region] (R-SCE-6805936) SSA2 [secretory granule lumen] (R-SCE-6801530) SSA2 [secretory granule lumen] (R-SCE-6801472-3) SSA2 [cytosol] (R-SCE-3371410-3) SSA2 [cytosol] (R-SCE-3371408-3) SSA2 [cytosol] (R-SCE-6792602-3) SSA2 [nucleoplasm] (R-SCE-5082380) SSA2 [nucleoplasm] (R-SCE-6792605-3) SSA2 [nucleoplasm] (R-SCE-912480-3) SSA2 [nucleoplasm] (R-SCE-5082367-3) SSA2 [nucleoplasm] (R-SCE-5252082-3) SSA2 [nucleoplasm] (R-SCE-5252088-3) SSA2 [nucleoplasm] (R-SCE-5252009-3) SSA2 [cytosol] (R-SCE-5251948-3)	0.527	2

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