E2 enzyme MMS2:UBC13 binds ubiquitin

Stable Identifier
R-SCE-9640470
Type
Reaction [binding]
Species
Saccharomyces cerevisiae
Compartment
General
SVG |   | PPTX  | SBGN
E2 enzyme MMS2:UBC13 binds ubiquitin

Ubiquitination is the covalent attachment of ubiquitin molecules to substrate proteins with three enzymatic steps - E1 ubiquitin activation, E2 ubiquitin conjugation and E3 ubiquitin protein ligase. MMS2 and UBC13 are E2 ubiquitin-conjugating enzymes that form a complex and bind ubiquitin molecules at K63. This leads to the additional binding of ubiquitin entities and formation of a polyubiquitin chain (Hofmann RM et al. 1999).

Literature References
Participants
Orthologous Events
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