Reactome | phospho-FUS3 [cytosol]

phospho-FUS3 [cytosol]

Stable Identifier

R-SCE-9635773-2

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

p-T185-MAPK1, P16892

Locations in the PathwayBrowser

Expand all

Signal Transduction (Saccharomyces cerevisiae)

- MAPK family signaling cascades (Saccharomyces cerevisiae)
  - MAPK1/MAPK3 signaling (Saccharomyces cerevisiae)
    - RAF/MAP kinase cascade (Saccharomyces cerevisiae)
      - Negative regulation of MAPK pathway (Saccharomyces cerevisiae)
        
        PTPN7 dephosphorylates p-T,Y-MAPKs (Saccharomyces cerevisiae)
        
        PTPN7:p-T-MAPK dimers [cytosol] (Saccharomyces cerevisiae)
        
        p-T-MAPK dimers [cytosol] (Saccharomyces cerevisiae)
        
        p-T185-MAPK1 dimer [cytosol] (Saccharomyces cerevisiae)
        
        Homologues of p-T185-MAPK1 [cytosol] (Saccharomyces cerevisiae)
        
        phospho-FUS3 [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P16892

Gene Names

FUS3

Reference Genes

BioGPS Gene:852265 FUS3

ENSEMBL:YBL016W

KEGG:sce:YBL016W FUS3

Monarch:852265 FUS3

NCBI Gene:852265 FUS3

SGD:YBL016W

UCSC:P16892 FUS3

Reference Transcript

RefSeq:NM_001178256.1 FUS3

Other Identifiers

852265

GO:0000165

GO:0000749

GO:0000750

GO:0001403

GO:0003674

GO:0004672

GO:0004674

GO:0004707

GO:0005515

GO:0005524

GO:0005575

GO:0005634

GO:0005737

GO:0005739

GO:0006468

GO:0007050

GO:0008150

GO:0010468

GO:0010494

GO:0010526

GO:0016301

GO:0016740

GO:0030427

GO:0035556

GO:0042221

GO:0042597

GO:0042802

GO:0043167

GO:0043332

GO:0043409

GO:0046777

GO:0046827

GO:0051049

GO:0051301

GO:0071507

GO:0106310

Participates

as a member of

Homologues of p-T185-MAPK1 [cytosol] (Saccharomyces cerevisiae)

Other forms of this molecule

phospho-FUS3 [nucleoplasm]

phospho-FUS3 [cytosol]

FUS3 [cytosol]

phospho-FUS3 [nucleoplasm]

phospho-FUS3 [cytosol]

FUS3 [nucleoplasm]

phospho-FUS3 [cytosol]

FUS3 [cytosol]

phospho-FUS3 [cytosol]

phospho-FUS3 [nucleoplasm]

FUS3 [ficolin-1-rich granule lumen]

FUS3 [extracellular region]

FUS3 [azurophil granule lumen]

phospho-FUS3 [nucleoplasm]

FUS3 [nucleoplasm]

phospho-FUS3 [nucleoplasm]

phospho-FUS3 [cytosol]

FUS3 [cytosol]

FUS3 [nucleoplasm]

FUS3 [cytosol]

Inferred From

p-T185-MAPK1 [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 185 (in Homo sapiens)

Coordinate

185

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Cross References

RefSeq

NP_009537.1

ENSEMBL

YBL016W_mRNA, YBL016W, YBL016W

PRO

P16892

PDB

2F49, 2B9F, 2B9I, 2B9H, 2B9J, 2F9G, 2FA2

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06784	7	phospho-STE7 [cytosol] (R-SCE-5674490) phospho-STE7 [cytosol] (R-SCE-109848) phospho-STE7 [cytosol] (R-SCE-112374) phospho-STE7 [cytosol] (R-SCE-112339) STE7 [cytosol] (R-SCE-59502) phospho-STE7 [cytosol] (R-SCE-169292) phospho-STE7 [cytosol] (R-SCE-109837)	0.932	15
UniProt:P32917 STE5			0.91	11
UniProt:P23561	1	STE11 [cytosol] (R-SCE-167709)	0.721	6
UniProt:P16892	20	phospho-FUS3 [nucleoplasm] (R-SCE-112354-2) phospho-FUS3 [nucleoplasm] (R-SCE-112359-2) phospho-FUS3 [cytosol] (R-SCE-109842-2) phospho-FUS3 [cytosol] (R-SCE-109853-2) FUS3 [cytosol] (R-SCE-59282-2) FUS3 [cytosol] (R-SCE-59284-2) phospho-FUS3 [nucleoplasm] (R-SCE-198738) phospho-FUS3 [cytosol] (R-SCE-198721) FUS3 [nucleoplasm] (R-SCE-199961) FUS3 [nucleoplasm] (R-SCE-73724-2) FUS3 [nucleoplasm] (R-SCE-199960-2) phospho-FUS3 [cytosol] (R-SCE-9635773-2) phospho-FUS3 [cytosol] (R-SCE-9635775-2) FUS3 [cytosol] (R-SCE-4411330-2) phospho-FUS3 [cytosol] (R-SCE-4411398-2) phospho-FUS3 [nucleoplasm] (R-SCE-4411376-2) FUS3 [ficolin-1-rich granule lumen] (R-SCE-6800964-2) FUS3 [extracellular region] (R-SCE-6806250-2) FUS3 [azurophil granule lumen] (R-SCE-6799225-2) phospho-FUS3 [nucleoplasm] (R-SCE-5692665-2)	0.592	2
UniProt:P14681	20	phospho-KSS1 [nucleoplasm] (R-SCE-112354) phospho-KSS1 [nucleoplasm] (R-SCE-112359) phospho-KSS1 [cytosol] (R-SCE-109842) phospho-KSS1 [cytosol] (R-SCE-109853) KSS1 [cytosol] (R-SCE-59282) KSS1 [cytosol] (R-SCE-59284) KSS1 [nucleoplasm] (R-SCE-73724) KSS1 [nucleoplasm] (R-SCE-199960) phospho-KSS1 [cytosol] (R-SCE-9635773) phospho-KSS1 [cytosol] (R-SCE-9635775) KSS1 [cytosol] (R-SCE-4411330) phospho-KSS1 [cytosol] (R-SCE-4411398) phospho-KSS1 [nucleoplasm] (R-SCE-4411376) KSS1 [ficolin-1-rich granule lumen] (R-SCE-6800964) KSS1 [extracellular region] (R-SCE-6806250) KSS1 [azurophil granule lumen] (R-SCE-6799225) phospho-KSS1 [nucleoplasm] (R-SCE-5692665) KSS1 [nucleoplasm] (R-SCE-5692686) phospho-KSS1 [nucleoplasm] (R-SCE-5687015) phospho-KSS1 [nucleoplasm] (R-SCE-5687022)	0.573	2
UniProt:Q12329 HSP42			0.564	2
UniProt:P19882 HSP60	7	HSP60 [mitochondrial matrix] (R-SCE-1252181) HSP60 [mitochondrial inner membrane] (R-SCE-1267982) HSP60 precursor [mitochondrial inner membrane] (R-SCE-1267967) HSP60 precursor [mitochondrial intermembrane space] (R-SCE-1252158) HSP60 [cytosol] (R-SCE-1252153) HSP60 [mitochondrial matrix] (R-SCE-8986171) HSP60 [mitochondrial matrix] (R-SCE-1299448)	0.564	2
UniProt:P15992 HSP26			0.564	2
UniProt:Q03063 DIG1			0.547	2
UniProt:Q03373 DIG2			0.547	2
UniProt:P08539	5	GPA1 [plasma membrane] (R-SCE-167451) GPA1 [plasma membrane] (R-SCE-170657) GPA1 [plasma membrane] (R-SCE-167453) GPA1 [plasma membrane] (R-SCE-167450) GPA1 [plasma membrane] (R-SCE-167446)	0.544	2
UniProt:P33306 BCK2			0.499	2

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