Reactome | GCN2 dimer [cytosol]

GCN2 dimer [cytosol]

Stable Identifier

R-SCE-9635308

Type

Complex

Species

Saccharomyces cerevisiae

Compartment

cytosol

Literature References

PubMed ID	Title	Journal	Year
11250908	The tRNA-binding moiety in GCN2 contains a dimerization domain that interacts with the kinase domain and is required for tRNA binding and kinase activation Francklyn, CS, Hinnebusch, AG, Dong, J, Hu, C, Qiu, H	EMBO J.	2001
15010461	Dimerization is required for activation of eIF2 kinase Gcn2 in response to diverse environmental stress conditions Wek, RC, Narasimhan, J, Staschke, KA	J. Biol. Chem.	2004
9566889	Dimerization by translation initiation factor 2 kinase GCN2 is mediated by interactions in the C-terminal ribosome-binding region and the protein kinase domain Hinnebusch, AG, Garcia-Barrio, MT, Qiu, H	Mol. Cell. Biol.	1998

Participants

components

x 2 GCN2 [cytosol] (Saccharomyces cerevisiae)

Participates

as a component of

Inferred To

EIF2AK4 dimer [cytosol] (Homo sapiens)

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