Reactome | phospho-MCM1 [nucleoplasm]

phospho-MCM1 [nucleoplasm]

Stable Identifier

R-SCE-9612518

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

p-S103 SRF, P11746

Locations in the PathwayBrowser

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Signal Transduction (Saccharomyces cerevisiae)

- Signaling by Receptor Tyrosine Kinases (Saccharomyces cerevisiae)
  - Signaling by NTRKs (Saccharomyces cerevisiae)
    - Signaling by NTRK1 (TRKA) (Saccharomyces cerevisiae)
      - Nuclear Events (kinase and transcription factor activation) (Saccharomyces cerevisiae)
        
        NGF-stimulated transcription (Saccharomyces cerevisiae)
        
        SGK phosphorylates SRF (Saccharomyces cerevisiae)
        
        phospho-MCM1 [nucleoplasm] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P11746

Gene Names

MCM1

Reference Genes

BioGPS Gene:855060 MCM1

ENSEMBL:YMR043W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YMR043W MCM1

Monarch:855060 MCM1

NCBI Gene:855060 MCM1

SGD:YMR043W

Reference Transcript

RefSeq:NM_001182540.1 MCM1

Other Identifiers

1770949_at

855060

9576_at

GO:0000122

GO:0000278

GO:0000785

GO:0000790

GO:0000821

GO:0000978

GO:0000981

GO:0000987

GO:0001077

GO:0001078

GO:0001102

GO:0001103

GO:0001133

GO:0001197

GO:0001198

GO:0001227

GO:0001228

GO:0003674

GO:0003677

GO:0003688

GO:0003700

GO:0005515

GO:0005575

GO:0005634

GO:0005694

GO:0005737

GO:0005829

GO:0006260

GO:0006270

GO:0006366

GO:0006520

GO:0006525

GO:0007049

GO:0007532

GO:0008134

GO:0008150

GO:0031494

GO:0043565

GO:0044377

GO:0045944

GO:0046983

GO:0061629

GO:0090282

GO:0090571

GO:0090575

GO:0140313

GO:1900465

GO:1900466

Participates

as an output of

SGK phosphorylates SRF (Saccharomyces cerevisiae)

Other forms of this molecule

MCM1 [nucleoplasm]

Inferred From

p-S103 SRF [nucleoplasm] (Homo sapiens)

Modified Residues

Name

O-phospho-L-serine at 103 (in Homo sapiens)

Coordinate

103

PsiMod Name

O-phospho-L-serine [MOD:00046]

PsiMod Definition

A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.

Cross References

RefSeq

NP_013757.1

PRO

P11746

PDB

1MNM

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P02309	14	HHF2 [nucleoplasm] (R-SCE-4570518) HHF2 [nucleoplasm] (R-SCE-212078) HHF2 [nucleoplasm] (R-SCE-4568744) HHF2 [nucleoplasm] (R-SCE-5229015) HHF2 [nucleoplasm] (R-SCE-4754243) HHF2 [nucleoplasm] (R-SCE-4754240) HHF2 [nucleoplasm] (R-SCE-5651656) HHF2 [nucleoplasm] (R-SCE-427469) HHF2 [nucleoplasm] (R-SCE-4568748) HHF2 [nucleoplasm] (R-SCE-4568758) HHF2 [nucleoplasm] (R-SCE-3451124) HHF2 [nucleoplasm] (R-SCE-5423110) HHF2 [nucleoplasm] (R-SCE-5651652) HHF2 [nucleoplasm] (R-SCE-181902)	0.669	3
UniProt:P0CY08 MTAL2			0.623	2
UniProt:P07250	4	IP6K3 [cytosol] (R-SCE-1604594) IP6K1 [cytosol] (R-SCE-1604591) IP6K1 [nucleoplasm] (R-SCE-2023952) IP6K2 [nucleoplasm] (R-SCE-1015687)	0.547	2
UniProt:P11746	2	phospho-MCM1 [nucleoplasm] (R-SCE-9612518) MCM1 [nucleoplasm] (R-SCE-5666000)	0.547	2
UniProt:P43609	2	SMARCC1 [nucleoplasm] (R-SCE-389257) SMARCC2 [nucleoplasm] (R-SCE-389263-2)	0.527	2
UniProt:P05085 ARGR2			0.527	2
UniProt:P10592	20	SSA2 [cytosol] (R-SCE-264476) SSA2 [nucleoplasm] (R-SCE-5082380) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801512-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801496-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801494) SSA2 [extracellular region] (R-SCE-6805872-3) SSA2 [extracellular region] (R-SCE-6806500-3) SSA2 [extracellular region] (R-SCE-6805936) SSA2 [secretory granule lumen] (R-SCE-6801530) SSA2 [secretory granule lumen] (R-SCE-6801472-3) SSA2 [cytosol] (R-SCE-3371410-3) SSA2 [cytosol] (R-SCE-3371408-3) SSA2 [cytosol] (R-SCE-6792602-3) SSA2 [nucleoplasm] (R-SCE-6792605-3) SSA2 [nucleoplasm] (R-SCE-912480-3) SSA2 [nucleoplasm] (R-SCE-5082367-3) SSA2 [nucleoplasm] (R-SCE-5252082-3) SSA2 [nucleoplasm] (R-SCE-5252088-3) SSA2 [nucleoplasm] (R-SCE-5252009-3) SSA2 [cytosol] (R-SCE-5251948-3)	0.527	2
UniProt:P11484	17	HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-4) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-4) HSPA1A [extracellular region] (R-SCE-6805872-4) HSPA6 [extracellular region] (R-SCE-6806500-4) HSPA6 [secretory granule lumen] (R-SCE-6801472-4) HSPA1L [cytosol] (R-SCE-3371410-4) HSPA2 [cytosol] (R-SCE-3371408-4) HSPA1A [cytosol] (R-SCE-6792602-4) HSPA1A [nucleoplasm] (R-SCE-6792605-4) HSPA2 [nucleoplasm] (R-SCE-912480-4) HSPA1L [nucleoplasm] (R-SCE-5082367-4) HSPA14 [nucleoplasm] (R-SCE-5252082-4) HSPA6 [nucleoplasm] (R-SCE-5252088-4) HSPA13 [nucleoplasm] (R-SCE-5252009-4) HSPA14 [cytosol] (R-SCE-5251948-4) HSPA13 [cytosol] (R-SCE-5251981-4) HSPA6 [cytosol] (R-SCE-3371521-4)	0.527	2
UniProt:Q03940 RUVB1			0.527	2
UniProt:Q12464 RUVB2			0.527	2
UniProt:P32832 RSC7			0.527	2

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