Reactome | UBI4 [cytosol]

UBI4 [cytosol]

Stable Identifier

R-SCE-939169

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

Ub-63-UBA52(1-76), P0CG63

Locations in the PathwayBrowser for interactor UniProt:P40343 VPS27

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External Reference Information

External Reference

UniProt:P0CG63 UBI4

Gene Names

UBI4, SCD2, YLL039C

Chain

chain:1-76, chain:77-152, chain:153-228, chain:229-304, chain:305-380, propeptide:-

Reference Genes

BioGPS Gene:850620 UBI4

KEGG:sce:YLL039C UBI4

Monarch:850620 UBI4

NCBI Gene:850620 UBI4

UCSC:P0CG63 UBI4

Reference Transcript

RefSeq:NM_001181859.1 UBI4

Other Identifiers

10392_at

1772373_at

850620

GO:0000209

GO:0003674

GO:0005515

GO:0005575

GO:0005634

GO:0005737

GO:0005777

GO:0005829

GO:0006513

GO:0008150

GO:0008152

GO:0016567

GO:0016579

GO:0019899

GO:0019941

GO:0030437

GO:0031386

GO:0031625

GO:0043008

GO:0043934

GO:0051321

GO:0051603

GO:0070647

Participates

as an output of

PSMD14 cleaves K63-linked ubiquitin (Saccharomyces cerevisiae)

as a repeated unit of

K63polyUb [cytosol] (Saccharomyces cerevisiae)

Other forms of this molecule

UBI4(1-76) [cytosol]

UBI4 [cytosol]

UBI4 [nucleoplasm]

UBI4 [cytosol]

UBI4 [nucleoplasm]

UBI4 [cytosol]

UBI4 [endosome membrane]

phospho-UBI4 [cytosol]

UBI4 [cytosol]

phospho-UBI4 [nucleoplasm]

UBI4 [cytosol]

UBI4 [endocytic vesicle membrane]

Inferred From

K63-Ub [cytosol] (Homo sapiens)

Ub-63-UBA52(1-76) [cytosol] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine at 63 (in Homo sapiens)

Coordinate

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_013061.1

ENSEMBL

YLL039C, YLL039C_mRNA

PRO

P0CG63

PDB

1ZW7, 4Q5E, 3OLM, 8DAT, 4HCN, 4NNJ, 1OTR, 2JWZ, 2JT4, 2KDI, 2L00, 8DAW, 3L0W, 8DAU, 1WR1, 3CMM, 1Q0W, 2G3Q, 4Q5H, 8DAV, 3L10

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P32628	2	RAD23 [nucleoplasm] (R-SCE-62590) RAD23 [nucleoplasm] (R-SCE-5688076)	0.858	8
UniProt:P48510	2	DSK2 [cytosol] (R-SCE-8866006) DSK2 [cytosol] (R-SCE-8866007)	0.766	7
UniProt:P40087 DDI1			0.658	3
UniProt:P40343 VPS27			0.618	5
UniProt:P15108	6	HSP90AA1 [ficolin-1-rich granule lumen] (R-SCE-6801470-2) HSP90AA1 [extracellular region] (R-SCE-3221946-2) HSP90AA1 [secretory granule lumen] (R-SCE-6801515-2) HSP90AA1 [plasma membrane] (R-SCE-534996-2) HSP90AA1 [nucleoplasm] (R-SCE-5082401-2) HSP90AA1 [cytosol] (R-SCE-192864-2)	0.609	3
UniProt:P23301	3	HYP2 [cytosol] (R-SCE-204650-2) HYP2 [cytosol] (R-SCE-204612-2) HYP2 [cytosol] (R-SCE-3149584-2)	0.609	2
UniProt:P54787	6	VPS9 [cytosol] (R-SCE-8875290) VPS9 [cytosol] (R-SCE-8875419) VPS9 [cytosol] (R-SCE-8875287) VPS9 [cytosol] (R-SCE-8875293) VPS9 [cytosol] (R-SCE-8875292) VPS9 [cytosol] (R-SCE-8871123)	0.527	2
UniProt:P48365	2	GYP7 [cytosol] (R-SCE-8854150) GYP7 [autophagosome] (R-SCE-8854607)	0.524	2

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