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phospho-PolyUb,p-S,T-ORC1 [cytosol]
Stable Identifier
R-SCE-9032195
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
cytosol
Synonyms
P54784
Locations in the PathwayBrowser for interactor UniProt:P04912
Expand all
Cell Cycle (Saccharomyces cerevisiae)
Cell Cycle, Mitotic (Saccharomyces cerevisiae)
S Phase (Saccharomyces cerevisiae)
Synthesis of DNA (Saccharomyces cerevisiae)
Switching of origins to a post-replicative state (Saccharomyces cerevisiae)
Orc1 removal from chromatin (Saccharomyces cerevisiae)
Ubiquitinated Orc1 enters the cytosol (Saccharomyces cerevisiae)
phospho-PolyUb,p-S,T-ORC1 [cytosol] (Saccharomyces cerevisiae)
Ubiquitinated Orc1 is degraded by the proteasome (Saccharomyces cerevisiae)
phospho-PolyUb,p-S,T-ORC1 [cytosol] (Saccharomyces cerevisiae)
DNA Replication (Saccharomyces cerevisiae)
Synthesis of DNA (Saccharomyces cerevisiae)
Switching of origins to a post-replicative state (Saccharomyces cerevisiae)
Orc1 removal from chromatin (Saccharomyces cerevisiae)
Ubiquitinated Orc1 enters the cytosol (Saccharomyces cerevisiae)
phospho-PolyUb,p-S,T-ORC1 [cytosol] (Saccharomyces cerevisiae)
Ubiquitinated Orc1 is degraded by the proteasome (Saccharomyces cerevisiae)
phospho-PolyUb,p-S,T-ORC1 [cytosol] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P54784 ORC1
Gene Names
ORC1, YML065W
Chain
chain:1-914
Reference Genes
BioGPS Gene:854937 ORC1
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YML065W ORC1
Monarch:854937 ORC1
NCBI Gene:854937 ORC1
Reference Transcript
RefSeq:NM_001182424.1 ORC1
Other Identifiers
1770816_at
854937
9689_at
GO:0000166
GO:0000278
GO:0003674
GO:0003677
GO:0003682
GO:0003688
GO:0005515
GO:0005524
GO:0005575
GO:0005634
GO:0005654
GO:0005656
GO:0005664
GO:0005694
GO:0006260
GO:0006267
GO:0006270
GO:0006325
GO:0008150
GO:0016787
GO:0016887
GO:0023052
GO:0030466
GO:0031261
GO:0031491
GO:0032993
GO:0033314
GO:0043007
GO:0043167
GO:0046872
GO:0051726
GO:0140657
Participates
as an input of
Ubiquitinated Orc1 is degraded by the proteasome (Saccharomyces cerevisiae)
as an output of
Ubiquitinated Orc1 enters the cytosol (Saccharomyces cerevisiae)
Other forms of this molecule
ORC1 [nucleoplasm]
yORC1 [nucleoplasm]
ORC1 [cytosol]
phospho-p-S,T-ORC1 [nucleoplasm]
phospho-PolyUb,p-S,T-ORC1 [nucleoplasm]
Inferred From
PolyUb,p-S,T-ORC1 [cytosol]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at unknown position
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-threonine at unknown position
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
ubiquitinylated lysine (polyubiquitin chain [nucleoplasm]) at unknown position
Modification
polyubiquitin chain [nucleoplasm]
PsiMod Name
ubiquitinylated lysine [MOD:01148]
PsiMod Definition
A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.
Cross References
RefSeq
NP_013646.1
OpenTargets
ENSG00000085840
PRO
P54784
PDB
6RQC
,
7TJK
,
6WGG
,
7TJF
,
7TJJ
,
1ZHI
,
7TJI
,
6WGC
,
5V8F
,
7E9F
,
7MCA
,
1M4Z
,
6OM3
,
7TJH
,
6WGI
,
5ZR1
,
7E9C
,
1ZBX
Interactors (13)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P54791 ORC4
2
yORC4 [nucleoplasm]
(R-SCE-9749319)
ORC4 [nucleoplasm]
(R-SCE-68519)
0.87
19
UniProt:P38826 ORC6
1
yORC6 [nucleoplasm]
(R-SCE-9749321)
0.803
18
UniProt:P32833 ORC2
2
yORC2 [nucleoplasm]
(R-SCE-9749316)
ORC2 [nucleoplasm]
(R-SCE-68405)
0.767
19
UniProt:P54790 ORC3
2
yORC3 [nucleoplasm]
(R-SCE-9749325)
ORC3 [nucleoplasm]
(R-SCE-68513)
0.767
11
UniProt:P50874 ORC5
2
yORC5 [nucleoplasm]
(R-SCE-9749322)
ORC5 [nucleoplasm]
(R-SCE-68516)
0.767
11
UniProt:P09119 CDC6
5
CDC6 [cytosol]
(R-SCE-113566)
phospho-p-CDC6 [cytosol]
(R-SCE-68583)
phospho-p-CDC6 [nucleoplasm]
(R-SCE-5661317)
yCDC6 [nucleoplasm]
(R-SCE-9749328)
CDC6 [nucleoplasm]
(R-SCE-68542)
0.652
3
UniProt:P02309
14
HHF2 [nucleoplasm]
(R-SCE-4570518)
HHF2 [nucleoplasm]
(R-SCE-212078)
HHF2 [nucleoplasm]
(R-SCE-4568744)
HHF2 [nucleoplasm]
(R-SCE-5229015)
HHF2 [nucleoplasm]
(R-SCE-4754243)
HHF2 [nucleoplasm]
(R-SCE-4754240)
HHF2 [nucleoplasm]
(R-SCE-5651656)
HHF2 [nucleoplasm]
(R-SCE-427469)
HHF2 [nucleoplasm]
(R-SCE-4568748)
HHF2 [nucleoplasm]
(R-SCE-4568758)
HHF2 [nucleoplasm]
(R-SCE-5423110)
HHF2 [nucleoplasm]
(R-SCE-3451124)
HHF2 [nucleoplasm]
(R-SCE-5651652)
HHF2 [nucleoplasm]
(R-SCE-181902)
0.564
2
UniProt:P02294
16
HTB2 [nucleoplasm]
(R-SCE-181898-2)
HTB2 [nucleoplasm]
(R-SCE-181916-2)
HTB2 [nucleoplasm]
(R-SCE-3364019-2)
HTB2 [nucleoplasm]
(R-SCE-3364020-2)
HTB2 [nucleoplasm]
(R-SCE-4568637-2)
HTB2 [nucleoplasm]
(R-SCE-4568639-2)
HTB2 [nucleoplasm]
(R-SCE-4568629-2)
HTB2 [nucleoplasm]
(R-SCE-4568632-2)
HTB2 [nucleoplasm]
(R-SCE-4568647-2)
HTB2 [nucleoplasm]
(R-SCE-4568631-2)
HTB2 [nucleoplasm]
(R-SCE-4568615-2)
HTB2 [nucleoplasm]
(R-SCE-4568624-2)
HTB2 [nucleoplasm]
(R-SCE-4549272-2)
HTB2 [nucleoplasm]
(R-SCE-4549263-2)
HTB2 [nucleoplasm]
(R-SCE-6782554-2)
HTB2 [nucleoplasm]
(R-SCE-6782561-2)
0.564
3
UniProt:Q96EY1-3 DNAJA3
0.556
3
UniProt:P11484
17
HSPA1L [cytosol]
(R-SCE-3371410-4)
HSPA2 [cytosol]
(R-SCE-3371408-4)
HSPA1A [cytosol]
(R-SCE-6792602-4)
HSPA6 [ficolin-1-rich granule lumen]
(R-SCE-6801512-4)
HSPA1A [ficolin-1-rich granule lumen]
(R-SCE-6801496-4)
HSPA1A [extracellular region]
(R-SCE-6805872-4)
HSPA6 [extracellular region]
(R-SCE-6806500-4)
HSPA6 [secretory granule lumen]
(R-SCE-6801472-4)
HSPA1A [nucleoplasm]
(R-SCE-6792605-4)
HSPA2 [nucleoplasm]
(R-SCE-912480-4)
HSPA1L [nucleoplasm]
(R-SCE-5082367-4)
HSPA14 [nucleoplasm]
(R-SCE-5252082-4)
HSPA6 [nucleoplasm]
(R-SCE-5252088-4)
HSPA13 [nucleoplasm]
(R-SCE-5252009-4)
HSPA14 [cytosol]
(R-SCE-5251948-4)
HSPA13 [cytosol]
(R-SCE-5251981-4)
HSPA6 [cytosol]
(R-SCE-3371521-4)
0.527
2
UniProt:P21691 SIR1
0.527
3
UniProt:P04912
20
HTA2 [nucleoplasm]
(R-SCE-6782532-2)
HTA2 [nucleoplasm]
(R-SCE-6782493-2)
HTA2 [nucleoplasm]
(R-SCE-6782514-2)
HTA2 [nucleoplasm]
(R-SCE-6782531-2)
HTA2 [nucleoplasm]
(R-SCE-4568572-2)
HTA2 [nucleoplasm]
(R-SCE-4568611-2)
HTA2 [nucleoplasm]
(R-SCE-4568583-2)
HTA2 [nucleoplasm]
(R-SCE-4568598-2)
HTA2 [nucleoplasm]
(R-SCE-5244584-2)
HTA2 [nucleoplasm]
(R-SCE-5244581-2)
HTA2 [nucleoplasm]
(R-SCE-5244538-2)
HTA2 [nucleoplasm]
(R-SCE-5244562-2)
HTA2 [nucleoplasm]
(R-SCE-5244557-2)
HTA2 [nucleoplasm]
(R-SCE-5244574-2)
HTA2 [nucleoplasm]
(R-SCE-5244542-2)
HTA2 [nucleoplasm]
(R-SCE-5244576-2)
HTA2 [nucleoplasm]
(R-SCE-5244590-2)
HTA2 [nucleoplasm]
(R-SCE-5244621-2)
HTA2 [nucleoplasm]
(R-SCE-5244589-2)
HTA2 [nucleoplasm]
(R-SCE-5244628-2)
0.527
2
UniProt:P02293
16
HTB1 [nucleoplasm]
(R-SCE-6782561)
HTB1 [nucleoplasm]
(R-SCE-6782554)
HTB1 [nucleoplasm]
(R-SCE-4549263)
HTB1 [nucleoplasm]
(R-SCE-4549272)
HTB1 [nucleoplasm]
(R-SCE-4568624)
HTB1 [nucleoplasm]
(R-SCE-181898)
HTB1 [nucleoplasm]
(R-SCE-181916)
HTB1 [nucleoplasm]
(R-SCE-3364019)
HTB1 [nucleoplasm]
(R-SCE-3364020)
HTB1 [nucleoplasm]
(R-SCE-4568637)
HTB1 [nucleoplasm]
(R-SCE-4568639)
HTB1 [nucleoplasm]
(R-SCE-4568629)
HTB1 [nucleoplasm]
(R-SCE-4568632)
HTB1 [nucleoplasm]
(R-SCE-4568647)
HTB1 [nucleoplasm]
(R-SCE-4568631)
HTB1 [nucleoplasm]
(R-SCE-4568615)
0.527
2
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