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Me3K525-EEF2 [cytosol]
Stable Identifier
R-SCE-8932237
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
cytosol
Synonyms
P32324
Locations in the PathwayBrowser for interactor UniProt:P48362 HGH1
Expand all
Metabolism of proteins (Saccharomyces cerevisiae)
Post-translational protein modification (Saccharomyces cerevisiae)
Protein methylation (Saccharomyces cerevisiae)
EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 (Saccharomyces cerevisiae)
Me3K525-EEF2 [cytosol] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P32324 EFT1
Gene Names
EFT1, YOR133W, O3317, YOR3317W, EFT2, YDR385W
Chain
chain:1-842
Reference Genes
BioGPS Gene:851993 EFT1
BioGPS Gene:854301 EFT1
KEGG:sce:YDR385W EFT1
KEGG:sce:YOR133W EFT1
Monarch:851993 EFT1
Monarch:854301 EFT1
NCBI Gene:851993 EFT1
NCBI Gene:854301 EFT1
UCSC:P32324 EFT1
Reference Transcript
RefSeq:NM_001180693.1 EFT1
RefSeq:NM_001183552.1 EFT1
Other Identifiers
1777413_s_at
8425_s_at
851993
854301
GO:0000166
GO:0003674
GO:0003723
GO:0003746
GO:0003924
GO:0005515
GO:0005525
GO:0005575
GO:0005737
GO:0005829
GO:0006412
GO:0006414
GO:0006417
GO:0008135
GO:0008150
GO:0016787
GO:0019843
GO:0042802
GO:0043022
GO:0043167
GO:0045901
GO:0051087
GO:1990145
GO:1990904
Participates
as an output of
EEF2KMT transfers 3xCH3 from 3xAdoMet to EEF2 (Saccharomyces cerevisiae)
Other forms of this molecule
EEF2 [secretory granule lumen]
EEF2 [extracellular region]
EEF2 [ficolin-1-rich granule lumen]
EEF2 [cytosol]
aminocarboxypropyl EEF2 [cytosol]
Me-diphthine EEF2 [cytosol]
nascent EEF2 [cytosol]
diphthine EEF2 [cytosol]
Me-diphthine EFT1 [cytosol]
diphthine EFT1 [cytosol]
Inferred From
Me3K525-EEF2 [cytosol]
(Homo sapiens)
Modified Residues
Name
dipthamide at 715 (in Homo sapiens)
Coordinate
715
PsiMod Name
dipthamide
PsiMod Definition
A protein modification that effectively converts an L-histidine residue to diphthamide.
Name
N6,N6,N6-trimethyl-L-lysine at 525 (in Homo sapiens)
Coordinate
525
PsiMod Name
N6,N6,N6-trimethyl-L-lysine [MOD:00083]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6,N6,N6-trimethyl-L-lysine.
Cross References
ENSEMBL
YDR385W_mRNA
,
YDR385W
,
YOR133W
,
YOR133W_mRNA
PRO
P32324
PDB
6GQB
,
1N0V
,
1U2R
,
1N0U
,
3B82
,
6GQV
,
2P8Z
,
3DNY
,
4V4B
,
2E1R
,
2NPF
,
5JUS
,
2P8W
,
2P8X
,
3B78
,
8CDR
,
2P8Y
,
5JUO
,
3B8H
,
1ZM9
,
1ZM4
,
5JUU
,
5JUT
,
1ZM3
,
1ZM2
,
8EVS
,
2ZIT
,
8EVQ
,
5JUP
,
8EUB
,
8EWB
,
6GQ1
,
8EVR
Interactors (22)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P48362 HGH1
0.78
9
UniProt:P40487
1
DPH1 [cytosol]
(R-SCE-5358384)
0.704
25
UniProt:P32324 EFT1
11
EEF2 [secretory granule lumen]
(R-SCE-6801504)
EEF2 [extracellular region]
(R-SCE-6806499)
EEF2 [ficolin-1-rich granule lumen]
(R-SCE-6801513)
EEF2 [cytosol]
(R-SCE-156901)
aminocarboxypropyl EEF2 [cytosol]
(R-SCE-5358478)
Me-diphthine EEF2 [cytosol]
(R-SCE-5367025)
nascent EEF2 [cytosol]
(R-SCE-5358472)
diphthine EEF2 [cytosol]
(R-SCE-5358501)
Me-diphthine EFT1 [cytosol]
(R-SCE-5367013)
diphthine EFT1 [cytosol]
(R-SCE-5367015)
Me3K525-EEF2 [cytosol]
(R-SCE-8932237)
0.678
59
UniProt:P32461
1
DPH2 [cytosol]
(R-SCE-5358368)
0.678
27
UniProt:P42842 EMW1
0.659
5
UniProt:P05317
1
RPP0 [cytosol]
(R-SCE-72396)
0.622
3
UniProt:P32469
1
DPH5 [cytosol]
(R-SCE-5358485)
0.595
3
UniProt:P40150
17
HSPA6 [cytosol]
(R-SCE-3371521-6)
HSPA13 [cytosol]
(R-SCE-5251981-6)
HSPA14 [cytosol]
(R-SCE-5251948-6)
HSPA13 [nucleoplasm]
(R-SCE-5252009-6)
HSPA6 [nucleoplasm]
(R-SCE-5252088-6)
HSPA14 [nucleoplasm]
(R-SCE-5252082-6)
HSPA1L [nucleoplasm]
(R-SCE-5082367-6)
HSPA2 [nucleoplasm]
(R-SCE-912480-6)
HSPA1A [nucleoplasm]
(R-SCE-6792605-6)
HSPA1A [extracellular region]
(R-SCE-6805872-6)
HSPA1A [ficolin-1-rich granule lumen]
(R-SCE-6801496-6)
HSPA6 [ficolin-1-rich granule lumen]
(R-SCE-6801512-6)
HSPA6 [extracellular region]
(R-SCE-6806500-6)
HSPA6 [secretory granule lumen]
(R-SCE-6801472-6)
HSPA1A [cytosol]
(R-SCE-6792602-6)
HSPA2 [cytosol]
(R-SCE-3371408-6)
HSPA1L [cytosol]
(R-SCE-3371410-6)
0.564
2
UniProt:Q02821
2
SRP1 [cytosol]
(R-SCE-180612)
SRP1 [cytosol]
(R-SCE-9734672)
0.564
2
UniProt:P41940 MPG1
0.547
2
UniProt:P38011
1
ASC1 [cytosol]
(R-SCE-5626956)
0.528
2
UniProt:P32905 RPS0A
3
RPS0A [cytosol]
(R-SCE-72389)
RPS0A [cytosol]
(R-SCE-9633103)
RPS0A [nucleoplasm]
(R-SCE-6798722)
0.528
2
UniProt:P25491
3
SOH-C149,C150-DNAJA1 [cytosol]
(R-SCE-9857072)
DNAJA4 [cytosol]
(R-SCE-3371578)
DNAJA2 [cytosol]
(R-SCE-3371555)
0.527
4
UniProt:P35184
1
SQT1 [cytosol]
(R-SCE-9674636)
0.527
3
UniProt:P39077
1
CCT3 [cytosol]
(R-SCE-390463)
0.527
3
UniProt:Q03330
2
KAT2B [nucleoplasm]
(R-SCE-352430)
KAT2A [nucleoplasm]
(R-SCE-3006516)
0.527
3
UniProt:Q00362
2
CDC55 [cytosol]
(R-SCE-377253)
CDC55 [nucleoplasm]
(R-SCE-1564978)
0.527
2
UniProt:P10592
20
SSA2 [cytosol]
(R-SCE-264476)
SSA2 [nucleoplasm]
(R-SCE-5082380)
SSA2 [cytosol]
(R-SCE-3371410-3)
SSA2 [cytosol]
(R-SCE-3371408-3)
SSA2 [cytosol]
(R-SCE-6792602-3)
SSA2 [secretory granule lumen]
(R-SCE-6801530)
SSA2 [secretory granule lumen]
(R-SCE-6801472-3)
SSA2 [extracellular region]
(R-SCE-6806500-3)
SSA2 [extracellular region]
(R-SCE-6805936)
SSA2 [ficolin-1-rich granule lumen]
(R-SCE-6801512-3)
SSA2 [ficolin-1-rich granule lumen]
(R-SCE-6801496-3)
SSA2 [ficolin-1-rich granule lumen]
(R-SCE-6801494)
SSA2 [extracellular region]
(R-SCE-6805872-3)
SSA2 [nucleoplasm]
(R-SCE-6792605-3)
SSA2 [nucleoplasm]
(R-SCE-912480-3)
SSA2 [nucleoplasm]
(R-SCE-5082367-3)
SSA2 [nucleoplasm]
(R-SCE-5252082-3)
SSA2 [nucleoplasm]
(R-SCE-5252088-3)
SSA2 [nucleoplasm]
(R-SCE-5252009-3)
SSA2 [cytosol]
(R-SCE-5251948-3)
0.527
3
UniProt:P10591
17
SSA1 [cytosol]
(R-SCE-3371410-2)
SSA1 [cytosol]
(R-SCE-3371408-2)
SSA1 [cytosol]
(R-SCE-6792602-2)
SSA1 [secretory granule lumen]
(R-SCE-6801472-2)
SSA1 [extracellular region]
(R-SCE-6806500-2)
SSA1 [ficolin-1-rich granule lumen]
(R-SCE-6801512-2)
SSA1 [ficolin-1-rich granule lumen]
(R-SCE-6801496-2)
SSA1 [extracellular region]
(R-SCE-6805872-2)
SSA1 [nucleoplasm]
(R-SCE-6792605-2)
SSA1 [nucleoplasm]
(R-SCE-912480-2)
SSA1 [nucleoplasm]
(R-SCE-5082367-2)
SSA1 [nucleoplasm]
(R-SCE-5252082-2)
SSA1 [nucleoplasm]
(R-SCE-5252088-2)
SSA1 [nucleoplasm]
(R-SCE-5252009-2)
SSA1 [cytosol]
(R-SCE-5251948-2)
SSA1 [cytosol]
(R-SCE-5251981-2)
SSA1 [cytosol]
(R-SCE-3371521-2)
0.527
3
UniProt:P40413
1
CCT5 [cytosol]
(R-SCE-390447)
0.527
3
UniProt:P52286
2
SKP1 [cytosol]
(R-SCE-174150)
SKP1 [nucleoplasm]
(R-SCE-187538)
0.499
2
UniProt:P14120 RPL30
2
RPL30 [cytosol]
(R-SCE-72452)
RPL30 [cytosol]
(R-SCE-9633100)
0.46
2
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