Reactome | SPT15 [nucleoplasm]

SPT15 [nucleoplasm]

Stable Identifier

R-SCE-83718

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

TBP, P13393

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P13393 SPT15

Gene Names

SPT15, BTF1, TBP1, YER148W

Chain

initiator methionine:1, chain:2-240

Reference Genes

BioGPS Gene:856891 SPT15

KEGG:sce:YER148W SPT15

Monarch:856891 SPT15

NCBI Gene:856891 SPT15

UCSC:P13393 SPT15

Reference Transcript

RefSeq:NM_001179038.3 SPT15

Other Identifiers

856891

GO:0000126

GO:0000790

GO:0000979

GO:0000995

GO:0001016

GO:0001092

GO:0001102

GO:0001179

GO:0001188

GO:0003674

GO:0003677

GO:0003682

GO:0005515

GO:0005575

GO:0005634

GO:0005654

GO:0005667

GO:0005669

GO:0005672

GO:0006352

GO:0006359

GO:0006360

GO:0006367

GO:0008134

GO:0008150

GO:0008301

GO:0016251

GO:0032991

GO:0042790

GO:0045892

GO:0045944

GO:0051123

GO:0061629

GO:0070893

GO:0070898

GO:0097718

GO:0140297

Participates

as an input of

TBP and TFIIA bind TATA box on ESR1:estrogen bound TFF1 gene promoter (Saccharomyces cerevisiae)

as a component of

Other forms of this molecule

TATA-box factor [nucleoplasm]

Inferred From

TBP [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_011075.3

ENSEMBL

YER148W, YER148W, YER148W_mRNA

PRO

P13393

PDB

7OH9, 8H5B, 7OHA, 6GYM, 5FZ5, 6F40, 6F44, 6F41, 5SVA, 6CNB, 8FFZ, 8CEN, 8UMI, 8CEO, 4B0A, 7ML1, 8UOT, 5OQJ, 7ZS9, 8UOQ, 6GYK, 4V1O, 7ML2, 7O4I, 7O73, 1YTF, 7OHB, 1RM1, 1TBA, 6E16, 6F42, 6CNF, 1NH2, 5FYW, 6EU0, 6CND, 6CNC, 1YTB, 8UMH, 6TBM, 7Q5B, 5FMF, 7ML0, 7O72, 7ZSA, 1NGM, 7ZSB, 7ML4, 7O75, 7O4J, 5OQM, 6GYL, 4V1N, 7Z0O, 6E24, 1TBP

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P32333 BTAF1			0.855	9
UniProt:Q03761	1	TAF12 [nucleoplasm] (R-SCE-65555)	0.802	5
UniProt:P29056 BRF1	2	BRF [nucleoplasm] (R-SCE-111841) BRF1 [nucleoplasm] (R-SCE-65894)	0.77	4
UniProt:Q12030	1	TAF10 [nucleoplasm] (R-SCE-65551)	0.688	4
UniProt:P20434 RPB5	2	RPB5 [nucleoplasm] (R-SCE-83713) RPB5_YEAST [nucleoplasm] (R-SCE-111833)	0.667	3
UniProt:P46677	2	TAF1 [nucleoplasm] (R-SCE-65539) TAF1 [nucleoplasm] (R-SCE-212435)	0.643	4
UniProt:Q12464 RUVB2			0.591	3
UniProt:Q03940	1	RUVBL1 [nucleoplasm] (R-SCE-418323)	0.591	3
UniProt:P15108	6	HSP90AA1 [secretory granule lumen] (R-SCE-6801515-2) HSP90AA1 [extracellular region] (R-SCE-3221946-2) HSP90AA1 [ficolin-1-rich granule lumen] (R-SCE-6801470-2) HSP90AA1 [plasma membrane] (R-SCE-534996-2) HSP90AA1 [nucleoplasm] (R-SCE-5082401-2) HSP90AA1 [cytosol] (R-SCE-192864-2)	0.589	2
UniProt:Q04712 RRN11			0.589	2
UniProt:P50105	2	TAF4 [nucleoplasm] (R-SCE-65559) TAF4 [nucleoplasm] (R-SCE-65541)	0.564	2
UniProt:P40096 NCB1			0.564	2
UniProt:P38915	1	SPT8 [cytosol] (R-SCE-391290)	0.558	3
UniProt:Q01939	2	PSMC5 [cytosol] (R-SCE-68780) PSMC5 [nucleoplasm] (R-SCE-174312)	0.544	2
UniProt:P53040	1	TAF6 [nucleoplasm] (R-SCE-65545)	0.527	2
UniProt:P53067 IMB5			0.527	2
UniProt:Q05027	3	TAF9 [nucleoplasm] (R-SCE-8869460) TAF9 [nucleoplasm] (R-SCE-212404) TAF9 [nucleoplasm] (R-SCE-212452)	0.527	2
UniProt:P38129	2	TAF5 [cytosol] (R-SCE-9907973) TAF5 [nucleoplasm] (R-SCE-65543)	0.527	5
UniProt:P38304 MED8			0.525	3
UniProt:Q99278 MED11			0.495	3

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