Reactome | RPT5 [cytosol]

RPT5 [cytosol]

Stable Identifier

R-SCE-68774

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

PSMC3, P33297

Locations in the PathwayBrowser

Expand all

Immune System (Saccharomyces cerevisiae)

- Adaptive Immune System (Saccharomyces cerevisiae)
  - Class I MHC mediated antigen processing & presentation (Saccharomyces cerevisiae)
    - Antigen processing-Cross presentation (Saccharomyces cerevisiae)
      - Cross-presentation of soluble exogenous antigens (endosomes) (Saccharomyces cerevisiae)
        
        Proteasomal clevage of exogenous antigen (26S proteasome catalyst) (Saccharomyces cerevisiae)
        
        26S proteasome [cytosol] (Saccharomyces cerevisiae)
        
        19S regulatory particle [cytosol] (Saccharomyces cerevisiae)
        
        19S RP base [cytosol] (Saccharomyces cerevisiae)
        
        PSMC3:PSMC6 [cytosol] (Saccharomyces cerevisiae)
        
        RPT5 [cytosol] (Saccharomyces cerevisiae)
- Cytokine Signaling in Immune system (Saccharomyces cerevisiae)
  - TNFR2 non-canonical NF-kB pathway (Saccharomyces cerevisiae)
    - 26Sproteasome degrades K48polyUb-NIK (Saccharomyces cerevisiae)
      - 26S proteasome [cytosol] (Saccharomyces cerevisiae)
        
        19S regulatory particle [cytosol] (Saccharomyces cerevisiae)
        
        19S RP base [cytosol] (Saccharomyces cerevisiae)
        
        PSMC3:PSMC6 [cytosol] (Saccharomyces cerevisiae)
        
        RPT5 [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P33297

Gene Names

RPT5

Reference Genes

BioGPS Gene:854284 RPT5

ENSEMBL:YOR117W

KEGG:sce:YOR117W RPT5

Monarch:854284 RPT5

NCBI Gene:854284 RPT5

SGD:YOR117W

UCSC:P33297 RPT5

Reference Transcript

RefSeq:NM_001183536.3 RPT5

Other Identifiers

854284

GO:0000166

GO:0000502

GO:0003674

GO:0005515

GO:0005524

GO:0005575

GO:0005634

GO:0005737

GO:0006511

GO:0008150

GO:0008540

GO:0010498

GO:0010604

GO:0016787

GO:0016887

GO:0036402

GO:0043161

GO:0043167

GO:0045899

GO:0051603

GO:0070682

GO:0080090

GO:1901800

Participates

as an input of

PSMC3 binds PSMC6 (Saccharomyces cerevisiae)

as a component of

PSMC3:PSMC6 [cytosol] (Saccharomyces cerevisiae)

Other forms of this molecule

RPT5 [secretory granule lumen]

RPT5 [extracellular region]

RPT5 [ficolin-1-rich granule lumen]

Inferred From

PSMC3 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_014760.3

ENSEMBL

YOR117W, YOR117W, YOR117W_mRNA

PRO

P33297

PDB

5MP9, 5MPA, 6J30, 6J2C, 6J2N, 5MPB, 6EF0, 5MPC, 4CR4, 3JCP, 4CR3, 3JCO, 6FVU, 6FVT, 6FVY, 6FVX, 4CR2, 6EF1, 6EF2, 6J2Q, 6J2X, 7QO5, 5WVI, 6EF3, 5WVK, 7QO4, 5A5B, 3WHK, 6FVW, 6FVV, 3WHL

Interactors (29)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P53549	1	RPT4 [cytosol] (R-SCE-68783)	0.924	11
UniProt:P33298	1	RPT3 [cytosol] (R-SCE-68777)	0.855	7
UniProt:P40555	1	NAS2 [cytosol] (R-SCE-68810)	0.835	8
UniProt:P38348 HSM3			0.822	7
UniProt:P38764	4	RPN1 [cytosol] (R-SCE-68796) RPN1 [secretory granule lumen] (R-SCE-6800919) RPN1 [extracellular region] (R-SCE-6806479) RPN1 [ficolin-1-rich granule lumen] (R-SCE-6800435)	0.809	17
UniProt:P53196 RPN14			0.803	6
UniProt:P33299	4	RPT1 [cytosol] (R-SCE-68771) RPT1 [secretory granule lumen] (R-SCE-6800994) RPT1 [extracellular region] (R-SCE-6806472) RPT1 [ficolin-1-rich granule lumen] (R-SCE-6800421)	0.798	6
UniProt:P50086	1	NAS6 [cytosol] (R-SCE-3640824-3)	0.784	5
UniProt:P38886	1	RPN10 [cytosol] (R-SCE-68800)	0.723	8
UniProt:P32628	2	RAD23 [nucleoplasm] (R-SCE-62590) RAD23 [nucleoplasm] (R-SCE-5688076)	0.688	5
UniProt:P43588	4	RPN11 [cytosol] (R-SCE-68722) RPN11 [secretory granule lumen] (R-SCE-6800926) RPN11 [extracellular region] (R-SCE-6806511) RPN11 [ficolin-1-rich granule lumen] (R-SCE-6800419)	0.688	6
UniProt:P40327	1	RPT2 [cytosol] (R-SCE-68768)	0.678	6
UniProt:Q01939	2	RPT6 [cytosol] (R-SCE-68780) RPT6 [nucleoplasm] (R-SCE-174312)	0.678	15
UniProt:Q12377	4	RPN6 [cytosol] (R-SCE-68790) RPN6 [secretory granule lumen] (R-SCE-6800943) RPN6 [extracellular region] (R-SCE-6806441) RPN6 [ficolin-1-rich granule lumen] (R-SCE-6800436)	0.669	14
UniProt:Q04062	4	RPN9 [cytosol] (R-SCE-68794) RPN9 [secretory granule lumen] (R-SCE-6800983) RPN9 [extracellular region] (R-SCE-6806469) RPN9 [ficolin-1-rich granule lumen] (R-SCE-6800413)	0.669	7
UniProt:Q06103	4	RPN7 [cytosol] (R-SCE-68804) RPN7 [secretory granule lumen] (R-SCE-6801036) RPN7 [extracellular region] (R-SCE-6806486) RPN7 [ficolin-1-rich granule lumen] (R-SCE-6800440)	0.669	4
UniProt:Q12250	4	RPN5 [cytosol] (R-SCE-68792) RPN5 [secretory granule lumen] (R-SCE-6800934) RPN5 [extracellular region] (R-SCE-6806480) RPN5 [ficolin-1-rich granule lumen] (R-SCE-6800416)	0.669	11
UniProt:P38737 ECM29			0.643	3
UniProt:Q08723	4	RPN8 [cytosol] (R-SCE-68806) RPN8 [secretory granule lumen] (R-SCE-6801008) RPN8 [extracellular region] (R-SCE-6806488) RPN8 [ficolin-1-rich granule lumen] (R-SCE-6800406)	0.564	7
UniProt:P43593	1	UBP6 [cytosol] (R-SCE-5689541)	0.564	25
UniProt:O94742 SEM1			0.564	15
UniProt:P32565	3	RPN2 [cytosol] (R-SCE-68786) RPN2 [azurophil granule lumen] (R-SCE-6798741) RPN2 [extracellular region] (R-SCE-6806194)	0.564	8
UniProt:Q9Y2J4 AMOTL2	1	AMOTL2 [cytosol] (R-HSA-2028606)	0.556	3
UniProt:P62333 PSMC6	2	PSMC6 [cytosol] (R-HSA-68783) PSMC6 [nucleoplasm] (R-HSA-174319)	0.556	3
UniProt:Q9P2K3-2 RCOR3			0.556	3
UniProt:P18848 ATF4	2	ATF4 [nucleoplasm] (R-HSA-381016) ATF4 [cytosol] (R-HSA-381084)	0.556	3
UniProt:O13563 RPN13			0.527	2
UniProt:P32496	1	RPN12 [cytosol] (R-SCE-68808)	0.527	2
UniProt:P43583 BLM10			0.508	2

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