Reactome | Ghost homologue of ORC6 [nucleoplasm]

Ghost homologue of ORC6 [nucleoplasm]

Stable Identifier

R-SCE-68539

Type

Genes and Transcripts [GenomeEncodedEntity]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Locations in the PathwayBrowser

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Cell Cycle (Saccharomyces cerevisiae)

- Cell Cycle, Mitotic (Saccharomyces cerevisiae)
  - Mitotic G1 phase and G1/S transition (Saccharomyces cerevisiae)
    - G1/S Transition (Saccharomyces cerevisiae)
      - Activation of the pre-replicative complex (Saccharomyces cerevisiae)
        
        CDK and DDK associate with the Mcm10:pre-replicative complex (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Cdc45 associates with the pre-replicative complex at the origin (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        DNA polymerase alpha:primase binds at the origin (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        DNA polymerase epsilon binds at the origin (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Saccharomyces cerevisiae)
        
        MCM10:pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDT1:CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDT1:CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
  - S Phase (Saccharomyces cerevisiae)
    - Synthesis of DNA (Saccharomyces cerevisiae)
      - Switching of origins to a post-replicative state (Saccharomyces cerevisiae)
        
        Orc1 removal from chromatin (Saccharomyces cerevisiae)
        
        Orc1 is phosphorylated by cyclin A/CDK2 (Saccharomyces cerevisiae)
        
        pre-replicative complex (Orc1-minus) [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDT1:CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)

DNA Replication (Saccharomyces cerevisiae)

- DNA Replication Pre-Initiation (Saccharomyces cerevisiae)
  - Activation of the pre-replicative complex (Saccharomyces cerevisiae)
    - CDK and DDK associate with the Mcm10:pre-replicative complex (Saccharomyces cerevisiae)
      - CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
      - MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
    - Cdc45 associates with the pre-replicative complex at the origin (Saccharomyces cerevisiae)
      - CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
      - CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
    - DNA Replication Factor A (RPA) associates with the pre-replicative complex at the origin (Saccharomyces cerevisiae)
      - CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
      - CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
    - DNA polymerase alpha:primase binds at the origin (Saccharomyces cerevisiae)
      - CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
    - DNA polymerase epsilon binds at the origin (Saccharomyces cerevisiae)
      - CDK:DDK:MCM10:active pre-replicative complex:CDC45:RPA1-4 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex:CDC45 [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDK:DDK:MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        MCM10:active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        active pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
    - Mcm10 associates with the pre-replicative complex, stabilizing Mcm2-7 (Saccharomyces cerevisiae)
      - MCM10:pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDT1:CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
      - pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDT1:CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
- Synthesis of DNA (Saccharomyces cerevisiae)
  - Switching of origins to a post-replicative state (Saccharomyces cerevisiae)
    - Orc1 removal from chromatin (Saccharomyces cerevisiae)
      - Orc1 is phosphorylated by cyclin A/CDK2 (Saccharomyces cerevisiae)
        
        pre-replicative complex (Orc1-minus) [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)
        
        pre-replicative complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDT1:CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        CDC6:ORC:origin complex [nucleoplasm] (Saccharomyces cerevisiae)
        
        ORC:origin of replication [nucleoplasm] (Saccharomyces cerevisiae)
        
        Ghost homologue of ORC6 [nucleoplasm] (Saccharomyces cerevisiae)

Participant Of

hasComponent

Inferred From

ORC6 [nucleoplasm] (Homo sapiens)