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phospho-p-S5,S7(CTD)-POLR2A [nucleoplasm]
Stable Identifier
R-SCE-6810226
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
nucleoplasm
Synonyms
P04050
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Saccharomyces cerevisiae)
RNA Polymerase II Transcription (Saccharomyces cerevisiae)
RNA polymerase II transcribes snRNA genes (Saccharomyces cerevisiae)
CDK7 phosphorylates serine-5 and serine-7 of heptad repeats in C-terminal domain of RNA polymerase II at snRNA promoter (Saccharomyces cerevisiae)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
RNA Polymerase II holoenzyme complex (p-Ser5,7 CTD) [nucleoplasm] (Saccharomyces cerevisiae)
phospho-p-S5,S7(CTD)-POLR2A [nucleoplasm] (Saccharomyces cerevisiae)
RPAP2 binds RNA polymerase II phosphorylated at serine-7 residues of heptad repeats in the C-terminal domain (Saccharomyces cerevisiae)
RNA polymerase II (phosphoserine-5,7):Initiation factors:CDK7:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
RNA Polymerase II holoenzyme complex (p-Ser5,7 CTD) [nucleoplasm] (Saccharomyces cerevisiae)
phospho-p-S5,S7(CTD)-POLR2A [nucleoplasm] (Saccharomyces cerevisiae)
RPAP2:RPRD1A,B:RPRD2:RNA polymerase II (phosphoserine-5,7):Initiation factors:snRNA gene [nucleoplasm] (Saccharomyces cerevisiae)
RNA polymerase II (phospho-Ser5,7 CTD):RPRD1A,B:RPRD2:RPAP2 [nucleoplasm] (Saccharomyces cerevisiae)
RNA Polymerase II holoenzyme complex (p-Ser5,7 CTD) [nucleoplasm] (Saccharomyces cerevisiae)
phospho-p-S5,S7(CTD)-POLR2A [nucleoplasm] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:P04050
Reference Genes
BioGPS Gene:851415
ENSEMBL:YDL140C
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YDL140C
Monarch:851415
NCBI Gene:851415
SGD:YDL140C
Reference Transcript
RefSeq:NM_001180200.1
Other Identifiers
1775403_at
6635_at
851415
GO:0000428
GO:0001055
GO:0001172
GO:0003674
GO:0003677
GO:0003899
GO:0003968
GO:0005515
GO:0005575
GO:0005634
GO:0005665
GO:0005737
GO:0005739
GO:0005773
GO:0006281
GO:0006351
GO:0006352
GO:0006354
GO:0006366
GO:0006367
GO:0006368
GO:0006974
GO:0008150
GO:0008270
GO:0010494
GO:0016740
GO:0016779
GO:0019985
GO:0034062
GO:0043167
GO:0046872
Participates
as a component of
RNA Polymerase II holoenzyme complex (p-Ser5,7 CTD) [nucleoplasm] (Saccharomyces cerevisiae)
Other forms of this molecule
phospho-p-S5(CTD)-POLR2A [nucleoplasm]
POLR2A [nucleoplasm]
phospho-Ub,p-S2,S5(CTD)-POLR2A [nucleoplasm]
phospho-p-3S-POLR2A [nucleoplasm]
phospho-p-S2,S5(CTD)-POLR2A [nucleoplasm]
Inferred From
p-S5,S7(CTD)-POLR2A [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-serine at 1843 (in Homo sapiens)
Coordinate
1843
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1845 (in Homo sapiens)
Coordinate
1845
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1850 (in Homo sapiens)
Coordinate
1850
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1857 (in Homo sapiens)
Coordinate
1857
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1864 (in Homo sapiens)
Coordinate
1864
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1871 (in Homo sapiens)
Coordinate
1871
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1878 (in Homo sapiens)
Coordinate
1878
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1892 (in Homo sapiens)
Coordinate
1892
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1899 (in Homo sapiens)
Coordinate
1899
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1906 (in Homo sapiens)
Coordinate
1906
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1913 (in Homo sapiens)
Coordinate
1913
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1920 (in Homo sapiens)
Coordinate
1920
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1927 (in Homo sapiens)
Coordinate
1927
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Name
O-phospho-L-serine at 1934 (in Homo sapiens)
Coordinate
1934
PsiMod Name
O-phospho-L-serine [MOD:00046]
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O-phospho-L-serine.
Cross References
RefSeq
NP_010141.1
PRO
P04050
PDB
4A3F
,
3M4O
,
6UQ1
,
6UQ2
,
7RIQ
,
2R7Z
,
3PO3
,
2YU9
,
7KED
,
3GTO
,
6UQ3
,
3RZO
,
7O72
,
7RIW
,
4BY7
,
1I50
,
4A3C
,
4BBS
,
4A3K
,
3S2D
,
5C4A
,
4A3J
,
4X67
,
7UIG
,
3HOZ
,
6GYL
,
2NVX
,
5LVF
,
7MKA
,
6UPY
,
2JA7
,
3GTJ
,
1TWH
,
3QT1
,
4V1M
,
6UQ0
,
6UPZ
,
2B8K
,
1TWF
,
3S1R
,
5W4U
,
3HOX
,
7O4L
,
3S17
,
3H3V
,
7ML1
,
4A3E
,
7ML2
,
5VVR
,
2VUM
,
4A3M
,
5OQJ
,
4Y7N
,
2R93
,
5U5Q
,
5VKO
,
3GTG
,
1I6H
,
3S14
,
4A3L
,
1TWC
,
6GYK
,
1K83
,
3HOV
,
2NVZ
,
3S2H
,
3J0K
,
2L0I
,
6BM2
,
3GTM
,
1Y1V
,
7KEF
,
3CQZ
,
7RIM
,
3S1N
,
8CEN
,
3K1F
,
7O75
,
7RIY
,
3S1M
,
4A93
,
3I4M
,
7MEI
,
4BXX
,
5M9D
,
7NKX
,
7O4J
,
7ZSA
,
2JA8
,
5C4X
,
3GTQ
,
2JA6
,
5W51
,
6BLO
,
5C3E
,
5OT2
,
3GTP
,
6BLP
,
7KEE
,
1WCM
,
7ZS9
,
6BQF
,
1NT9
,
1Y1Y
,
7O73
,
7RIX
,
2NVT
,
2R92
,
5FZ5
,
1NIK
,
6GYM
,
7UIF
,
3HOY
,
4BBR
,
4A3B
,
4V1O
,
2E2H
,
5FYW
,
1Y77
,
2NVQ
,
4GWQ
,
5FMF
,
4A3I
,
3GTK
,
7RIP
,
5C44
,
5SVA
,
1R9T
,
4A3G
,
2LO6
,
6NPW
,
4V1N
,
7ML0
,
2JA5
,
3S1Q
,
2B63
,
1TWG
,
3S16
,
3HOW
,
5C4J
,
7UI9
,
1R9S
,
5VKL
,
4X6A
,
5VVS
,
3PO2
,
5IP7
,
1R5U
,
2E2I
,
1TWA
,
7MK9
,
3S15
,
2E2J
,
6O6C
,
4A3D
,
7ML4
,
2NVY
,
3HOU
,
1PQV
,
3M3Y
,
3FKI
,
3I4N
,
6I84
,
1SFO
,
6BM4
,
4BY1
,
3GTL
,
6UPX
,
1Y1W
,
7O4I
,
4BXZ
,
3RZD
,
8CEO
,
7NKY
,
3J1N
,
7O4K
,
1I3Q
,
5IP9
,
7ZSB
,
5OQM
,
7UIO
,
3K7A
,
4Y52
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P27692
1
phospho-SPT5 [nucleoplasm]
(R-SCE-3009372)
0.822
12
UniProt:P22696
2
ESS1 [cytosol]
(R-SCE-9626823)
ESS1 [nucleoplasm]
(R-SCE-936016)
0.564
3
UniProt:P32914
1
SPT4 [nucleoplasm]
(R-SCE-64905)
0.564
7
UniProt:P39940
8
RSP5 [cytosol]
(R-SCE-975995)
RSP5 [cytosol]
(R-SCE-976003)
RSP5 [cytosol]
(R-SCE-173537)
RSP5 [cytosol]
(R-SCE-975972)
RSP5 [cytosol]
(R-SCE-976037)
RSP5 [cytosol]
(R-SCE-8851656)
RSP5 [cytosol]
(R-SCE-975992)
RSP5 [cytosol]
(R-SCE-6807279)
0.527
2
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