Reactome | NUS1 [endoplasmic reticulum membrane]

NUS1 [endoplasmic reticulum membrane]

Stable Identifier

R-SCE-6806946

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

endoplasmic reticulum membrane

Synonyms

NUS1, Q12063

Locations in the PathwayBrowser

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Metabolism of proteins (Saccharomyces cerevisiae)

- Post-translational protein modification (Saccharomyces cerevisiae)
  - Asparagine N-linked glycosylation (Saccharomyces cerevisiae)
    - Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Saccharomyces cerevisiae)
      - Synthesis of substrates in N-glycan biosythesis (Saccharomyces cerevisiae)
        
        Synthesis of Dolichyl-phosphate (Saccharomyces cerevisiae)
        
        DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP (Saccharomyces cerevisiae)
        
        DHDDS:NUS1 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
        
        NUS1 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:Q12063

Gene Names

NUS1

Reference Genes

BioGPS Gene:851334 NUS1

ENSEMBL:YDL193W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YDL193W NUS1

Monarch:851334 NUS1

NCBI Gene:851334 NUS1

SGD:YDL193W

Reference Transcript

RefSeq:NM_001180253.1 NUS1

Other Identifiers

1777255_at

6670_at

851334

GO:0003674

GO:0005575

GO:0005634

GO:0005635

GO:0005737

GO:0005783

GO:0005789

GO:0005811

GO:0006486

GO:0006629

GO:0008150

GO:0012505

GO:0016020

GO:0016021

GO:0016740

GO:0016765

GO:0019408

GO:0031965

GO:0045547

GO:1904423

Participates

as a component of

DHDDS:NUS1 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)

Inferred From

NUS1 [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_010088.1

OpenTargets

ENSG00000153989

PRO

Q12063

PDB

6JCN

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