Reactome | EXOSC10 [nucleoplasm]

EXOSC10 [nucleoplasm]

Stable Identifier

R-SCE-6791547

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

Q12149

Locations in the PathwayBrowser for interactor UniProt:Q02821

Expand all

External Reference Information

External Reference

UniProt:Q12149

Reference Genes

BioGPS Gene:854162

ENSEMBL:YOR001W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YOR001W

Monarch:854162

NCBI Gene:854162

SGD:YOR001W

Reference Transcript

RefSeq:NM_001183420.1

Other Identifiers

1778202_at

854162

8562_at

GO:0000166

GO:0000175

GO:0000176

GO:0000178

GO:0000467

GO:0000973

GO:0003674

GO:0003676

GO:0003723

GO:0003727

GO:0004518

GO:0004527

GO:0005515

GO:0005575

GO:0005634

GO:0005730

GO:0006139

GO:0006364

GO:0006396

GO:0006401

GO:0006417

GO:0008150

GO:0008270

GO:0008408

GO:0016787

GO:0019843

GO:0034473

GO:0034475

GO:0034476

GO:0042134

GO:0043144

GO:0043167

GO:0044237

GO:0071028

GO:0071033

GO:0071035

GO:0071036

GO:0071037

GO:0071038

GO:0071039

GO:0071040

GO:0071042

GO:0071044

GO:0071049

GO:0071051

Participates

as a component of

EXOSC10:C1D:MPHOSPH6 [nucleoplasm] (Saccharomyces cerevisiae)

This entity regulates

Positively

21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA (Saccharomyces cerevisiae)

Inferred From

EXOSC10 [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_014643.1

PRO

Q12149

PDB

5K36, 5VZJ, 4OO1, 2HBK, 5C0Y, 2HBJ, 6LQS, 6FT6, 2HBM, 6FSZ, 5C0X, 4IFD, 4WFD, 2HBL, 5C0W, 4WFC, 7D4I

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P53859 CSL4	2	CSL4 [nucleoplasm] (R-SCE-6791578) CSL4 [cytosol] (R-SCE-429841)	0.957	17
UniProt:Q08162 DIS3	2	DIS3 [nucleoplasm] (R-SCE-6791517) DIS3 [cytosol] (R-SCE-429935)	0.813	20
UniProt:P38792 RRP4	2	RRP4 [nucleoplasm] (R-SCE-6791582) RRP4 [cytosol] (R-SCE-429999)	0.813	9
UniProt:Q05636 RRP45	2	RRP45 [nucleoplasm] (R-SCE-6791577) RRP45 [cytosol] (R-SCE-429984)	0.758	32
UniProt:P25359 RRP43	2	RRP43 [nucleoplasm] (R-SCE-6791571) RRP43 [cytosol] (R-SCE-429912)	0.758	9
UniProt:P53256 RRP46	2	RRP46 [nucleoplasm] (R-SCE-6791550) RRP46 [cytosol] (R-SCE-429889)	0.758	15
UniProt:Q08285 RRP40	2	RRP40 [nucleoplasm] (R-SCE-6791572) RRP40 [cytosol] (R-SCE-430017)	0.758	6
UniProt:Q12277 RRP42	2	RRP42 [nucleoplasm] (R-SCE-6791543) RRP42 [cytosol] (R-SCE-430030)	0.758	7
UniProt:P46948 SKI6	2	SKI6 [nucleoplasm] (R-SCE-6791503) SKI6 [cytosol] (R-SCE-430013)	0.758	5
UniProt:P47047	1	SKIV2L2 [nucleoplasm] (R-SCE-6791189)	0.688	4
UniProt:Q06142	4	KAP95 [specific granule lumen] (R-SCE-6799646) KAP95 [extracellular region] (R-SCE-6806306) KAP95 [ficolin-1-rich granule lumen] (R-SCE-6800978) KAP95 [cytosol] (R-SCE-180733)	0.688	4
UniProt:P38801	1	LRP1 [nucleoplasm] (R-SCE-6791515)	0.669	11
UniProt:Q02821	2	SRP1 [cytosol] (R-SCE-180612) SRP1 [cytosol] (R-SCE-9734672)	0.669	4
UniProt:P48240 MTR3	2	MTR3 [nucleoplasm] (R-SCE-6791573) MTR3 [cytosol] (R-SCE-429921)	0.669	7
IntAct:EBI-11175111 SCR1 YEAST			0.564	2
UniProt:Q08965 BMS1	2	BMS1 [nucleoplasm] (R-SCE-6790636) BMS1 [nucleoplasm] (R-SCE-6790720)	0.528	2
UniProt:P53617 NRD1			0.499	4

Cite Us!