PPM2 methoxycarbonylates yW-58 yielding yW at nucleotide 37 of tRNA(Phe)

Stable Identifier
R-SCE-6783393
Type
Reaction [transition]
Species
Saccharomyces cerevisiae
Compartment
General
SVG |   | PPTX  | SBGN
PPM2 methoxycarbonylates yW-58 yielding yW at nucleotide 37 of tRNA(Phe)

PPM2 (TYW4) methoxycarbonylates yW-58 (7-((3S)-3-amino-3-(methoxycarbonyl)propyl)wyosine) at nucleotide 37 of tRNA(Phe) yielding yW (wyosine) (Suzuki et al. 2009). A molecule of carbon dioxide is incorporated during the reaction.

Literature References
PubMed ID Title Journal Year
19287006 Structural basis of tRNA modification with CO2 fixation and methylation by wybutosine synthesizing enzyme TYW4

Suzuki, T, Noma, A, Nureki, O, Ishitani, R, Suzuki, Y

Nucleic Acids Res. 2009
Participants
Event Information
Go Biological Process
Catalyst Activity

tRNA methyltransferase activity of PPM2 [cytoplasm]

Orthologous Events
Authored
Reviewed
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