Reactome | HSC82 [plasma membrane]

HSC82 [plasma membrane]

Stable Identifier

R-SCE-534996-2

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

plasma membrane

Synonyms

HSP90AA1, P15108

Locations in the PathwayBrowser

Expand all

Signal Transduction (Saccharomyces cerevisiae)

- Signaling by Receptor Tyrosine Kinases (Saccharomyces cerevisiae)
  - Signaling by VEGF (Saccharomyces cerevisiae)
    - VEGFA-VEGFR2 Pathway (Saccharomyces cerevisiae)
      - VEGFR2 mediated vascular permeability (Saccharomyces cerevisiae)
        
        AKT1 binds eNOS complex via HSP90 (Saccharomyces cerevisiae)
        
        eNOS:CaM:HSP90 [plasma membrane] (Saccharomyces cerevisiae)
        
        Homologues of HSP90AA1 [plasma membrane] (Saccharomyces cerevisiae)
        
        HSC82 [plasma membrane] (Saccharomyces cerevisiae)
        
        eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
        
        eNOS:CaM:HSP90 [plasma membrane] (Saccharomyces cerevisiae)
        
        Homologues of HSP90AA1 [plasma membrane] (Saccharomyces cerevisiae)
        
        HSC82 [plasma membrane] (Saccharomyces cerevisiae)
        
        AKT1 phosphorylates eNOS (Saccharomyces cerevisiae)
        
        eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
        
        eNOS:CaM:HSP90 [plasma membrane] (Saccharomyces cerevisiae)
        
        Homologues of HSP90AA1 [plasma membrane] (Saccharomyces cerevisiae)
        
        HSC82 [plasma membrane] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P15108

Gene Names

HSC82

Reference Genes

BioGPS Gene:855224 HSC82

ENSEMBL:YMR186W

KEGG Gene (Saccharomyces cerevisiae (strain YJM789)):YMR186W HSC82

Monarch:855224 HSC82

NCBI Gene:855224 HSC82

SGD:YMR186W

Reference Transcript

RefSeq:NM_001182692.1 HSC82

Other Identifiers

1775624_at

855224

9456_at

9457_g_at

GO:0000492

GO:0000723

GO:0003674

GO:0005524

GO:0005575

GO:0005737

GO:0005739

GO:0006457

GO:0006458

GO:0008150

GO:0009408

GO:0016787

GO:0016887

GO:0032200

GO:0034605

GO:0042026

GO:0042623

GO:0043167

GO:0043248

GO:0051082

Participates

as a member of

Homologues of HSP90AA1 [plasma membrane] (Saccharomyces cerevisiae)

Other forms of this molecule

HSC82 [secretory granule lumen]

HSC82 [extracellular region]

HSC82 [ficolin-1-rich granule lumen]

HSC82 [cytosol]

HSC82 [nucleoplasm]

HSC82 [cytosol]

Inferred From

HSP90AA1 [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_013911.1

ZINC - Substances

HSC82_YEAST

ZINC target

P15108

PRO

P15108

ZINC - Predictions - Purchasable

HSC82_YEAST

Interactors (10)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P15705	1	STI1 [cytosol] (R-SCE-443857)	0.758	22
UniProt:P53043	1	PPT1 [nucleoplasm] (R-SCE-5683410)	0.758	5
UniProt:P15303	4	SEC23 [ER to Golgi transport vesicle membrane] (R-SCE-204024) phospho-SEC23 [cytosol] (R-SCE-5685740) SEC23 [cytosol] (R-SCE-203972) SEC23 [endoplasmic reticulum membrane] (R-SCE-203976)	0.688	5
UniProt:P13393 SPT15	2	TATA-box factor [nucleoplasm] (R-SCE-111843) SPT15 [nucleoplasm] (R-SCE-83718)	0.589	2
UniProt:Q08446	1	SGT1 [cytosol] (R-SCE-874107)	0.589	3
UniProt:P38123	1	SWD3 [nucleoplasm] (R-SCE-1629838)	0.564	2
UniProt:Q02804 ARL3	4	ARL3 [cytosol] (R-SCE-6813851) AcM-ARL3 [cytosol] (R-SCE-6813860) ARL3 [cytosol] (R-SCE-6813853) ARL3 [trans-Golgi network membrane] (R-SCE-6813857)	0.564	2
UniProt:P06778	3	RAD52 [nucleoplasm] (R-SCE-62639) RAD52 [nucleoplasm] (R-SCE-4568909) phospho-RAD52 [nucleoplasm] (R-SCE-5686588)	0.564	2
UniProt:P25454	2	phospho-RAD51 [nucleoplasm] (R-SCE-5685231) RAD51 [nucleoplasm] (R-SCE-62637)	0.527	2
UniProt:Q03497	10	STE20 [cytosol] (R-SCE-428459-2) STE20 [plasma membrane] (R-SCE-211555-2) STE20 [cytosol] (R-SCE-428461-2) STE20 [cytosol] (R-SCE-428454-2) phospho-STE20 [cytosol] (R-SCE-5357471) STE20 [cytosol] (R-SCE-428457) STE20 [cytosol] (R-SCE-162629) STE20 [cytosol] (R-SCE-211604-2) phospho-STE20 [cytosol] (R-SCE-399819) phospho-STE20 [cytosol] (R-SCE-399824-2)	0.527	2