Reactome | TOP2B [nucleoplasm]

TOP2B [nucleoplasm]

Stable Identifier

R-SCE-4641359

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

P06786

Locations in the PathwayBrowser for interactor UniProt:Q06188 YL455

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External Reference Information

External Reference

UniProt:P06786

Reference Genes

BioGPS Gene:855636

ENSEMBL:YNL088W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YNL088W

Monarch:855636

NCBI Gene:855636

SGD:YNL088W

Reference Transcript

RefSeq:NM_001182926.3

Other Identifiers

1779900_at

855636

8944_at

GO:0000019

GO:0000166

GO:0000278

GO:0000712

GO:0000795

GO:0000819

GO:0003674

GO:0003677

GO:0003916

GO:0003918

GO:0005515

GO:0005524

GO:0005575

GO:0005634

GO:0005694

GO:0005737

GO:0005739

GO:0006259

GO:0006260

GO:0006265

GO:0006271

GO:0006310

GO:0006325

GO:0006333

GO:0007059

GO:0007131

GO:0008150

GO:0009303

GO:0016853

GO:0023052

GO:0031055

GO:0042802

GO:0043167

GO:0044774

GO:0046872

GO:0048285

GO:0051052

GO:0051321

GO:0051726

GO:0061982

GO:0097046

GO:0097047

GO:0140657

Participates

as an input of

SUMOylation of TOP2B with SUMO1 (Saccharomyces cerevisiae)

Other forms of this molecule

monoSUMO1-K-TOP2B [nucleoplasm]

monoSUMO1-K-TOP2A [nucleoplasm]

TOP2A [nucleoplasm]

Inferred From

TOP2B [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_014311.3

PRO

P06786

PDB

2RGR, 1BJT, 4GFH, 3L4K, 3L4J, 1PVG, 1BGW, 1QZR

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P06786	4	monoSUMO1-K-TOP2B [nucleoplasm] (R-SCE-4641297) TOP2B [nucleoplasm] (R-SCE-4641359) monoSUMO1-K-TOP2A [nucleoplasm] (R-SCE-4641367) TOP2A [nucleoplasm] (R-SCE-1362276)	0.825	5
UniProt:Q06188 YL455			0.564	4
UniProt:P04912	20	HTA2 [nucleoplasm] (R-SCE-6782532-2) HTA2 [nucleoplasm] (R-SCE-6782493-2) HTA2 [nucleoplasm] (R-SCE-6782514-2) HTA2 [nucleoplasm] (R-SCE-6782531-2) HTA2 [nucleoplasm] (R-SCE-4568572-2) HTA2 [nucleoplasm] (R-SCE-4568611-2) HTA2 [nucleoplasm] (R-SCE-4568583-2) HTA2 [nucleoplasm] (R-SCE-4568598-2) HTA2 [nucleoplasm] (R-SCE-5244584-2) HTA2 [nucleoplasm] (R-SCE-5244581-2) HTA2 [nucleoplasm] (R-SCE-5244538-2) HTA2 [nucleoplasm] (R-SCE-5244562-2) HTA2 [nucleoplasm] (R-SCE-5244557-2) HTA2 [nucleoplasm] (R-SCE-5244574-2) HTA2 [nucleoplasm] (R-SCE-5244542-2) HTA2 [nucleoplasm] (R-SCE-5244576-2) HTA2 [nucleoplasm] (R-SCE-5244590-2) HTA2 [nucleoplasm] (R-SCE-5244621-2) HTA2 [nucleoplasm] (R-SCE-5244589-2) HTA2 [nucleoplasm] (R-SCE-5244628-2)	0.564	8
UniProt:P02294	16	HTB2 [nucleoplasm] (R-SCE-181898-2) HTB2 [nucleoplasm] (R-SCE-181916-2) HTB2 [nucleoplasm] (R-SCE-3364019-2) HTB2 [nucleoplasm] (R-SCE-3364020-2) HTB2 [nucleoplasm] (R-SCE-4568637-2) HTB2 [nucleoplasm] (R-SCE-4568639-2) HTB2 [nucleoplasm] (R-SCE-4568629-2) HTB2 [nucleoplasm] (R-SCE-4568632-2) HTB2 [nucleoplasm] (R-SCE-4568647-2) HTB2 [nucleoplasm] (R-SCE-4568631-2) HTB2 [nucleoplasm] (R-SCE-4568615-2) HTB2 [nucleoplasm] (R-SCE-4568624-2) HTB2 [nucleoplasm] (R-SCE-4549272-2) HTB2 [nucleoplasm] (R-SCE-4549263-2) HTB2 [nucleoplasm] (R-SCE-6782554-2) HTB2 [nucleoplasm] (R-SCE-6782561-2)	0.564	4
UniProt:Q04636	1	POB3 [nucleoplasm] (R-SCE-65105)	0.564	3
UniProt:Q12159	2	YRA1 [nucleoplasm] (R-SCE-8850646) YRA1 [cytosol] (R-SCE-8850627)	0.564	6
UniProt:P32558	1	SPT16 [nucleoplasm] (R-SCE-112415)	0.564	9
UniProt:P10591	17	SSA1 [cytosol] (R-SCE-3371410-2) SSA1 [cytosol] (R-SCE-3371408-2) SSA1 [cytosol] (R-SCE-6792602-2) SSA1 [ficolin-1-rich granule lumen] (R-SCE-6801512-2) SSA1 [ficolin-1-rich granule lumen] (R-SCE-6801496-2) SSA1 [extracellular region] (R-SCE-6805872-2) SSA1 [extracellular region] (R-SCE-6806500-2) SSA1 [secretory granule lumen] (R-SCE-6801472-2) SSA1 [nucleoplasm] (R-SCE-6792605-2) SSA1 [nucleoplasm] (R-SCE-912480-2) SSA1 [nucleoplasm] (R-SCE-5082367-2) SSA1 [nucleoplasm] (R-SCE-5252082-2) SSA1 [nucleoplasm] (R-SCE-5252088-2) SSA1 [nucleoplasm] (R-SCE-5252009-2) SSA1 [cytosol] (R-SCE-5251948-2) SSA1 [cytosol] (R-SCE-5251981-2) SSA1 [cytosol] (R-SCE-3371521-2)	0.527	2
UniProt:P19454 CKA2	5	CKA2 [nucleoplasm] (R-SCE-6790631) CSNK2A1 [nucleoplasm] (R-SCE-6805057-2) CSNK2A2 [nucleoplasm] (R-SCE-6805065-2) CSNK2A2 [cytosol] (R-SCE-201721-2) CSNK2A1 [cytosol] (R-SCE-201713-2)	0.527	2
UniProt:P11484	17	HSPA1L [cytosol] (R-SCE-3371410-4) HSPA2 [cytosol] (R-SCE-3371408-4) HSPA1A [cytosol] (R-SCE-6792602-4) HSPA6 [ficolin-1-rich granule lumen] (R-SCE-6801512-4) HSPA1A [ficolin-1-rich granule lumen] (R-SCE-6801496-4) HSPA1A [extracellular region] (R-SCE-6805872-4) HSPA6 [extracellular region] (R-SCE-6806500-4) HSPA6 [secretory granule lumen] (R-SCE-6801472-4) HSPA1A [nucleoplasm] (R-SCE-6792605-4) HSPA2 [nucleoplasm] (R-SCE-912480-4) HSPA1L [nucleoplasm] (R-SCE-5082367-4) HSPA14 [nucleoplasm] (R-SCE-5252082-4) HSPA6 [nucleoplasm] (R-SCE-5252088-4) HSPA13 [nucleoplasm] (R-SCE-5252009-4) HSPA14 [cytosol] (R-SCE-5251948-4) HSPA13 [cytosol] (R-SCE-5251981-4) HSPA6 [cytosol] (R-SCE-3371521-4)	0.527	3
UniProt:P24583	20	PRKCD(330-676) [extracellular region] (R-SCE-6806199) PRKCD(1-329) [extracellular region] (R-SCE-6806226) PRKCD(1-329) [azurophil granule lumen] (R-SCE-6799219) PRKCD(330-676) [azurophil granule lumen] (R-SCE-6799221) phospho-p-T497,T638,S657-PRKCA [nucleoplasm] (R-SCE-5223292) phospho-p-T500,T642,S661-PRKCB [nucleoplasm] (R-SCE-5223294) phospho-p-T500,T642,S661-PRKCB [cytosol] (R-SCE-5218706) phospho-p-T410,T563-PRKCZ [cytosol] (R-SCE-5218698) phospho-p-T500-PRKCB [cytosol] (R-SCE-5218728) phospho-p-T507-PRKCD [cytosol] (R-SCE-5218746) phospho-p-T497-PRKCA [cytosol] (R-SCE-5218731) PRKCZ [cytosol] (R-SCE-58218) phospho-pS, p-T410-PRKCZ [cytosol] (R-SCE-9632824) phospho-p-T410-PRKCZ [cytosol] (R-SCE-437181) PRKCH [cytosol] (R-SCE-58208) phospho-p-T774-PKN1 [nucleoplasm] (R-SCE-5625721) PRKCB [cytosol] (R-SCE-58198) phospho-p-T507,S645,S664-PRKCD [cytosol] (R-SCE-5218734) PRKCB [plasma membrane] (R-SCE-156467) PRKCA [plasma membrane] (R-SCE-156469)	0.508	2

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