Reactome | ASF1 [nucleoplasm]

ASF1 [nucleoplasm]

Stable Identifier

R-SCE-417169

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

nucleoplasm

Synonyms

ASF1A, P32447

Locations in the PathwayBrowser for interactor UniProt:P22216

Expand all

Cellular responses to external stimuli (Saccharomyces cerevisiae)

- Cellular responses to stress (Saccharomyces cerevisiae)
  - Cellular Senescence (Saccharomyces cerevisiae)
    - DNA Damage/Telomere Stress Induced Senescence (Saccharomyces cerevisiae)
      - Formation of Senescence-Associated Heterochromatin Foci (SAHF) (Saccharomyces cerevisiae)
        
        Initiation of SAHF formation (Saccharomyces cerevisiae)
        
        ASF1 [nucleoplasm] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P32447

Gene Names

ASF1

Reference Genes

BioGPS Gene:853327 ASF1

ENSEMBL:YJL115W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YJL115W ASF1

Monarch:853327 ASF1

NCBI Gene:853327 ASF1

SGD:YJL115W

Reference Transcript

RefSeq:NM_001181548.1 ASF1

Other Identifiers

11134_at

1773349_at

853327

GO:0000781

GO:0001932

GO:0003674

GO:0005575

GO:0005634

GO:0005694

GO:0005737

GO:0005829

GO:0006325

GO:0006333

GO:0006334

GO:0006335

GO:0006336

GO:0006337

GO:0006348

GO:0006351

GO:0006354

GO:0006366

GO:0006468

GO:0008150

GO:0010468

GO:0016570

GO:0016573

GO:0018193

GO:0030466

GO:0031399

GO:0032968

GO:0033043

GO:0033523

GO:0035066

GO:0042393

GO:0043486

GO:0043543

GO:0043618

GO:0070647

Participant Of

input

Initiation of SAHF formation

hasComponent

HIRA:ASF1A:UBN1:CABIN1 [nucleoplasm]

Inferred From

ASF1A [nucleoplasm] (Homo sapiens)

Cross References

RefSeq

NP_012420.1

PRO

P32447

PDB

6AYZ, 5EII, 6AZ2, 5UEA, 6F0Y, 2HUE, 4EO5, 1WG3, 5UEK, 2IDC, 4ZBJ, 6O22, 1ROC, 5UCB, 2YGV

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P22216 RAD53			0.871	32
UniProt:P47171	1	HIR3 [nucleoplasm] (R-SCE-3878125)	0.76	11
UniProt:P61830	15	HHT2 [nucleoplasm] (R-SCE-427525) HHT2 [nucleoplasm] (R-SCE-417240) HHT2 [nucleoplasm] (R-SCE-4568747) HHT2 [nucleoplasm] (R-SCE-4568750) HHT2 [nucleoplasm] (R-SCE-4568755) HHT2 [nucleoplasm] (R-SCE-4568752) HHT2 [nucleoplasm] (R-SCE-4568924) HHT2 [nucleoplasm] (R-SCE-427407) phospho-HHT2 [nucleoplasm] (R-SCE-5625792) phospho-HHT2 [nucleoplasm] (R-SCE-5625754) HHT2 [nucleoplasm] (R-SCE-427744) HHT2 [nucleoplasm] (R-SCE-1214223) HHT2 [nucleoplasm] (R-SCE-212281) HHT2 [nucleoplasm] (R-SCE-212253) HHT2 [nucleoplasm] (R-SCE-1214225)	0.752	36
UniProt:P02309	14	HHF2 [nucleoplasm] (R-SCE-212078) HHF2 [nucleoplasm] (R-SCE-4570518) HHF2 [nucleoplasm] (R-SCE-4568744) HHF2 [nucleoplasm] (R-SCE-4568748) HHF2 [nucleoplasm] (R-SCE-427469) HHF2 [nucleoplasm] (R-SCE-4568758) HHF2 [nucleoplasm] (R-SCE-5229015) HHF2 [nucleoplasm] (R-SCE-4754243) HHF2 [nucleoplasm] (R-SCE-4754240) HHF2 [nucleoplasm] (R-SCE-5651656) HHF2 [nucleoplasm] (R-SCE-3451124) HHF2 [nucleoplasm] (R-SCE-2172676) HHF2 [nucleoplasm] (R-SCE-181902) HHF2 [nucleoplasm] (R-SCE-5651652)	0.752	18
UniProt:P32479	1	HIR1 [nucleoplasm] (R-SCE-2532790)	0.738	16
UniProt:Q04003 SAS4			0.721	5
UniProt:P40963	1	SAS2 [nucleoplasm] (R-SCE-3321979-2)	0.632	4
UniProt:P32480 HIR2			0.592	16
UniProt:Q01448	1	HPC2 [nucleoplasm] (R-SCE-2532791)	0.592	10
UniProt:P84233 Histone H3.2	2	Histone H3.2 [nucleoplasm] (R-XLA-4549227) Ack15-histone H3.2 [nucleoplasm] (R-XLA-4549248)	0.59	3
UniProt:P62799 H4			0.59	3
UniProt:P19454 CKA2	3	CKA2 [nucleoplasm] (R-SCE-6805065-2) CKA2 [nucleoplasm] (R-SCE-6790631) CKA2 [cytosol] (R-SCE-201721-2)	0.564	5
UniProt:P15790 CKA1	5	CKA1 [nucleoplasm] (R-SCE-6805057) CKA1 [nucleoplasm] (R-SCE-6790643) CKA1 [nucleoplasm] (R-SCE-6805065) CKA1 [cytosol] (R-SCE-201721) CKA1 [cytosol] (R-SCE-201713)	0.564	8
UniProt:Q99314	2	SAS5 [nucleoplasm] (R-SCE-8932789-3) SAS5 [nucleoplasm] (R-SCE-8932918-3)	0.547	2
UniProt:P40513 MAM33			0.527	2
UniProt:P10592	23	SSA2 [nucleoplasm] (R-SCE-5082380-3) SSA2 [cytosol] (R-SCE-264476-3) SSA2 [secretory granule lumen] (R-SCE-6801530-3) SSA2 [secretory granule lumen] (R-SCE-6801472-3) SSA2 [extracellular region] (R-SCE-6806500-3) SSA2 [extracellular region] (R-SCE-6805936-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801512-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801496-3) SSA2 [ficolin-1-rich granule lumen] (R-SCE-6801494-3) SSA2 [extracellular region] (R-SCE-6805872-3) SSA2 [nucleoplasm] (R-SCE-6792605-3) SSA2 [nucleoplasm] (R-SCE-912480-3) SSA2 [nucleoplasm] (R-SCE-5082367-3) SSA2 [nucleoplasm] (R-SCE-5252082-3) SSA2 [nucleoplasm] (R-SCE-5252088-3) SSA2 [nucleoplasm] (R-SCE-5252047-3) SSA2 [cytosol] (R-SCE-3371410-3) SSA2 [cytosol] (R-SCE-5251948-3) SSA2 [cytosol] (R-SCE-3371408-3) SSA2 [cytosol] (R-SCE-3371521-3) SSA2 [cytosol] (R-SCE-5251954-3) SSA2 [cytosol] (R-SCE-6792602-3) SSA2 [nucleoplasm] (R-SCE-8932217-3)	0.527	2
UniProt:P11484 SSB1			0.527	3
UniProt:P09938 RIR2			0.527	2
UniProt:P49723 RIR4			0.527	2
UniProt:P40161 RT106			0.499	5

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