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CDC53 [cytosol]
Stable Identifier
R-SCE-174230
Type
Protein [EntityWithAccessionedSequence]
Species
Saccharomyces cerevisiae
Compartment
cytosol
Synonyms
CUL1, Q12018
Locations in the PathwayBrowser for interactor UniProt:P52286
Expand all
Cell Cycle (Saccharomyces cerevisiae)
Cell Cycle, Mitotic (Saccharomyces cerevisiae)
Mitotic G2-G2/M phases (Saccharomyces cerevisiae)
G2/M Transition (Saccharomyces cerevisiae)
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis (Saccharomyces cerevisiae)
Formation of the SCF-FBXL7 complex (Saccharomyces cerevisiae)
CDC53 [cytosol] (Saccharomyces cerevisiae)
Transport of small molecules (Saccharomyces cerevisiae)
Iron uptake and transport (Saccharomyces cerevisiae)
CUL1, SKP1, FBXL5 bind (Saccharomyces cerevisiae)
CDC53 [cytosol] (Saccharomyces cerevisiae)
External Reference Information
External Reference
UniProt:Q12018
Gene Names
CDC53
Reference Genes
BioGPS Gene:851424 CDC53
ENSEMBL:YDL132W
KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YDL132W CDC53
Monarch:851424 CDC53
NCBI Gene:851424 CDC53
SGD:YDL132W
Reference Transcript
RefSeq:NM_001180191.1 CDC53
Other Identifiers
1779631_at
6596_at
851424
GO:0000082
GO:0000086
GO:0000278
GO:0000409
GO:0000781
GO:0003674
GO:0003677
GO:0003688
GO:0004842
GO:0005515
GO:0005575
GO:0005634
GO:0005694
GO:0005737
GO:0006325
GO:0006511
GO:0006974
GO:0007005
GO:0007049
GO:0007346
GO:0008053
GO:0008150
GO:0008643
GO:0009057
GO:0010828
GO:0016567
GO:0016740
GO:0019005
GO:0019222
GO:0019899
GO:0023052
GO:0030466
GO:0030674
GO:0031146
GO:0031335
GO:0031461
GO:0031509
GO:0031573
GO:0031625
GO:0032200
GO:0042221
GO:0042787
GO:0048284
GO:0051049
GO:0051301
GO:0051603
GO:0051726
GO:0055085
GO:0061630
GO:0070647
GO:0071406
Participates
as an input of
CUL1, SKP1, FBXL5 bind (Saccharomyces cerevisiae)
Formation of the SCF-FBXL7 complex (Saccharomyces cerevisiae)
as a component of
SKP1:CUL1:FBXL5 [cytosol] (Saccharomyces cerevisiae)
SKP1:CUL1:RBX1:FBXL18 [cytosol] (Saccharomyces cerevisiae)
SKP1:CUL1:RBX1:FBXL7 [cytosol] (Saccharomyces cerevisiae)
BTRC:CUL1:RBX1:SKP1 [cytosol] (Saccharomyces cerevisiae)
SCF E3 ubiquitin ligase [cytosol] (Saccharomyces cerevisiae)
CUL1:FBXW11:SKP1 [cytosol] (Saccharomyces cerevisiae)
as a member of
E3 ligases in proteasomal degradation [cytosol] (Saccharomyces cerevisiae)
Other forms of this molecule
CDC53 [cytosol]
CDC53 [nucleoplasm]
Inferred From
CUL1 [cytosol]
(Homo sapiens)
Cross References
RefSeq
NP_010150.1
PRO
Q12018
PDB
3O6B
,
3O2P
Interactors (19)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P52286
2
SKP1 [cytosol]
(R-SCE-174150)
SKP1 [nucleoplasm]
(R-SCE-187538)
0.93
30
UniProt:Q08273
3
RBX1 [nucleoplasm]
(R-SCE-1234142)
RNF7 (RBX2) [cytosol]
(R-SCE-8863132)
RBX1 [cytosol]
(R-SCE-180582)
0.899
9
UniProt:P39014 MET30
0.893
11
UniProt:P24814 GRR1
0.875
10
UniProt:P38352 SAF1
0.858
8
UniProt:P07834 CDC4
0.744
9
UniProt:Q92325 LAG2
0.727
10
UniProt:Q04511
1
UFO1 [cytosol]
(R-SCE-391305)
0.725
4
UniProt:Q06479
5
PolyUb-K109-FBXL7 [cytosol]
(R-SCE-8854053)
FBXL5 [cytosol]
(R-SCE-391295)
FBXL13 [cytosol]
(R-SCE-8862616)
FBXL7 [cytosol]
(R-SCE-8854032)
FBXL16 [cytosol]
(R-SCE-8862609)
0.725
5
UniProt:P14682
8
CDC34 [cytosol]
(R-SCE-8864180)
CDC34 [cytosol]
(R-SCE-8864149)
CDC34 [cytosol]
(R-SCE-8864170)
CDC34 [nucleoplasm]
(R-SCE-8864204)
CDC34 [nucleoplasm]
(R-SCE-8852125)
CDC34 [cytosol]
(R-SCE-947621)
CDC34 [cytosol]
(R-SCE-947627)
CDC34 [cytosol]
(R-SCE-947630)
0.723
38
UniProt:Q06640
6
PolyUb-K109-FBXL7 [cytosol]
(R-SCE-8854053-2)
FBXL5 [cytosol]
(R-SCE-391295-2)
FBXL20 [cytosol]
(R-SCE-8862591)
FBXL13 [cytosol]
(R-SCE-8862616-2)
FBXL7 [cytosol]
(R-SCE-8854032-2)
FBXL16 [cytosol]
(R-SCE-8862609-2)
0.643
3
UniProt:P47005 DAS1
0.643
3
UniProt:Q06682
2
UBX5 [cytosol]
(R-SCE-9755305)
UBX5 [cytosol]
(R-SCE-8956071)
0.564
2
UniProt:Q06150 BOP2
0.547
2
UniProt:Q12395
3
DCN1 [plasma membrane]
(R-SCE-8956204)
DCN1 [cytosol]
(R-SCE-8951782)
DCN1 [cytosol]
(R-SCE-8951781)
0.547
3
UniProt:P09232
3
PRB1 [endolysosome membrane]
(R-SCE-6784823)
PRB1 [lysosomal membrane]
(R-SCE-8855128)
PRB1 [extracellular region]
(R-SCE-6784727)
0.527
2
UniProt:P09435
17
SSA3 [cytosol]
(R-SCE-3371521)
SSA3 [cytosol]
(R-SCE-5251981)
SSA3 [cytosol]
(R-SCE-5251948)
SSA3 [nucleoplasm]
(R-SCE-5252009)
SSA3 [nucleoplasm]
(R-SCE-5252088)
SSA3 [nucleoplasm]
(R-SCE-5252082)
SSA3 [nucleoplasm]
(R-SCE-5082367)
SSA3 [nucleoplasm]
(R-SCE-912480)
SSA3 [nucleoplasm]
(R-SCE-6792605)
SSA3 [secretory granule lumen]
(R-SCE-6801472)
SSA3 [extracellular region]
(R-SCE-6806500)
SSA3 [extracellular region]
(R-SCE-6805872)
SSA3 [ficolin-1-rich granule lumen]
(R-SCE-6801496)
SSA3 [ficolin-1-rich granule lumen]
(R-SCE-6801512)
SSA3 [cytosol]
(R-SCE-6792602)
SSA3 [cytosol]
(R-SCE-3371408)
SSA3 [cytosol]
(R-SCE-3371410)
0.527
2
UniProt:Q12347
1
HRT3 [cytosol]
(R-SCE-8862608)
0.527
2
UniProt:Q03919
7
RUB1 [nucleoplasm]
(R-SCE-8952504)
RUB1 [cytosol]
(R-SCE-8951739)
RUB1 [cytosol]
(R-SCE-6782654)
RUB1 [cytosol]
(R-SCE-5690794)
RUB1 [cytosol]
(R-SCE-8951647)
RUB1 [cytosol]
(R-SCE-416969)
RUB1 [cytosol]
(R-SCE-4419895)
0.527
2
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