Reactome | phospho-p-T183,Y185-MAPK12 [cytosol]

phospho-p-T183,Y185-MAPK12 [cytosol]

Stable Identifier

R-SCE-171021

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

P32485

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P32485

Reference Genes

BioGPS Gene:850803

ENSEMBL:YLR113W

KEGG Gene (Saccharomyces cerevisiae (strain RM11-1a)):YLR113W

Monarch:850803

NCBI Gene:850803

SGD:YLR113W

Reference Transcript

RefSeq:NM_001182000.1

Other Identifiers

04150+2.7.11.24

4932.YLR113W

AAA34680.1

AAB67558.1

CAA61691.1

CAA97680.1

DAA09427.1

EntrezGene:850803

EntrezGene:HOG1

GO:0003674

GO:0003682

GO:0004672

GO:0004707

GO:0005516

GO:0005524

GO:0005575

GO:0005634

GO:0005737

GO:0006260

GO:0006351

GO:0006366

GO:0006468

GO:0006970

GO:0006972

GO:0006979

GO:0007186

GO:0007231

GO:0008150

GO:0009408

GO:0016241

GO:0016301

GO:0016740

GO:0023052

GO:0033262

GO:0034599

GO:0034605

GO:0042221

GO:0043167

GO:0045944

GO:0046685

GO:0051403

GO:0051726

GO:0061392

GO:0061393

GO:0071310

GO:0071470

IPR000719

IPR003527

IPR008271

IPR008352

IPR011009

IPR017441

IPR038783

NM_001182000.1

NP_013214.1

PF00069

PF12330

PR01773

SM00220

UPI00000520BA

YLR113W

YLR113W_mRNA

Participant Of

hasCandidate

Phospho-p38 MAPK [cytosol]

Other forms of this molecule

MAPK12 [nucleoplasm]

MAPK14 [secretory granule lumen]

MAPK14 [extracellular region]

MAPK14 [ficolin-1-rich granule lumen]

phospho-p-T180,Y182-MAPK13 [cytosol]

MAPK11 [cytosol]

MAPK13 [cytosol]

MAPK12 [cytosol]

phospho-p-T180,Y182-MAPK11 [cytosol]

MAPK11 [nucleoplasm]

MAPK14 [nucleoplasm]

phospho-p-T180,Y182-MAPK11 [nucleoplasm]

phospho-p-T180,Y182-MAPK14 [nucleoplasm]

MAPK14 [cytosol]

phospho-p-T180,Y182-MAPK14 [cytosol]

Inferred From

p-T183,Y185-MAPK12 [cytosol] (Homo sapiens)

Modified Residues

Name

O-phospho-L-threonine at 183 (in Homo sapiens)

Coordinate

183

PsiMod Name

O-phospho-L-threonine [MOD:00047]

PsiMod Definition

A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.

Name

O4'-phospho-L-tyrosine at 185 (in Homo sapiens)

Coordinate

185

PsiMod Name

O4'-phospho-L-tyrosine [MOD:00048]

PsiMod Definition

A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.

Cross References

RefSeq

NP_013214.1

IntEnz

2.7.11.24

PRO

P32485

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P38623 RCK2			0.765	7
UniProt:P38634 SIC1			0.639	4
UniProt:Q03213 HOT1			0.613	4
UniProt:P25588 MRC1			0.593	4
UniProt:P38622 RCK1			0.547	2
UniProt:P02829	11	HSP90AA1 [secretory granule lumen] (R-SCE-6801515) HSP90AB1 [secretory granule lumen] (R-SCE-6801477) HSP90AB1 [extracellular region] (R-SCE-6806463) HSP90AA1 [extracellular region] (R-SCE-3221946) HSP90AA1 [ficolin-1-rich granule lumen] (R-SCE-6801470) HSP90AB1 [ficolin-1-rich granule lumen] (R-SCE-6801491) HSP90AA1 [plasma membrane] (R-SCE-534996) HSP90AB1 [cytosol] (R-SCE-419617) HSP90AA1 [nucleoplasm] (R-SCE-5082401) HSP90AB1 [nucleoplasm] (R-SCE-5082399) HSP90AA1 [cytosol] (R-SCE-192864)	0.547	2
UniProt:P34244 HSL1			0.544	2
UniProt:Q01477	3	USP37 [nucleoplasm] (R-SCE-5697000) USP10 [nucleoplasm] (R-SCE-3222218) USP10 [cytosol] (R-SCE-6782974)	0.544	3
UniProt:P06784	8	MAP2K2 [cytosol] (R-SCE-59504) phospho-p-S,218, S222,T292 MAP2K1 [cytosol] (R-SCE-5674490) phospho-p-S222,S226-MAP2K2 [cytosol] (R-SCE-169292) phospho-p-S,T-MAP2K2 [cytosol] (R-SCE-109848) phospho-p-T286,T292-MAP2K1 [cytosol] (R-SCE-112374) phospho-p-S218,S222,T286,T292-MAP2K1 [cytosol] (R-SCE-112339) MAP2K1 [cytosol] (R-SCE-59502) phospho-p-S218,S222-MAP2K1 [cytosol] (R-SCE-109837)	0.499	2
UniProt:P19454 CKA2	1	CKA2 [nucleoplasm] (R-SCE-6790631)	0.462	3
UniProt:P15790 CKA1	1	CKA1 [nucleoplasm] (R-SCE-6790643)	0.462	2