Reactome | STE11 [cytosol]

STE11 [cytosol]

Stable Identifier

R-SCE-167709

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

MAP3K5, P23561

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P23561

Gene Names

STE11

Reference Genes

BioGPS Gene:851076 STE11

ENSEMBL:YLR362W

KEGG:sce:YLR362W STE11

Monarch:851076 STE11

NCBI Gene:851076 STE11

SGD:YLR362W

UCSC:P23561 STE11

Reference Transcript

RefSeq:NM_001182251.1 STE11

Other Identifiers

851076

GO:0000161

GO:0000165

GO:0000186

GO:0000196

GO:0000750

GO:0001402

GO:0001403

GO:0003674

GO:0004672

GO:0004674

GO:0004709

GO:0005515

GO:0005524

GO:0005575

GO:0005737

GO:0006468

GO:0006970

GO:0007124

GO:0007232

GO:0007254

GO:0008150

GO:0010525

GO:0016301

GO:0016740

GO:0019236

GO:0032093

GO:0035405

GO:0038066

GO:0042221

GO:0042802

GO:0043167

GO:0071474

GO:0071507

GO:0106310

Participates

as an output of

ROS oxidize thioredoxin and activate MAP3K5 (Saccharomyces cerevisiae)

as a component of

MAP3K5:TXN [cytosol] (Saccharomyces cerevisiae)

Inferred From

MAP3K5 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_013466.1

ENSEMBL

YLR362W, YLR362W, YLR362W_mRNA

PRO

P23561

PDB

1X9X, 1OW5

Interactors (8)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P25344 STE50			0.891	11
UniProt:P32917 STE5			0.814	9
UniProt:P16892	20	phospho-FUS3 [nucleoplasm] (R-SCE-112354-2) phospho-FUS3 [nucleoplasm] (R-SCE-112359-2) phospho-FUS3 [cytosol] (R-SCE-109842-2) phospho-FUS3 [cytosol] (R-SCE-109853-2) FUS3 [cytosol] (R-SCE-59282-2) FUS3 [cytosol] (R-SCE-59284-2) phospho-FUS3 [nucleoplasm] (R-SCE-198738) phospho-FUS3 [cytosol] (R-SCE-198721) FUS3 [nucleoplasm] (R-SCE-199961) FUS3 [nucleoplasm] (R-SCE-73724-2) FUS3 [nucleoplasm] (R-SCE-199960-2) phospho-FUS3 [cytosol] (R-SCE-9635773-2) phospho-FUS3 [cytosol] (R-SCE-9635775-2) FUS3 [cytosol] (R-SCE-4411330-2) phospho-FUS3 [cytosol] (R-SCE-4411398-2) phospho-FUS3 [nucleoplasm] (R-SCE-4411376-2) FUS3 [ficolin-1-rich granule lumen] (R-SCE-6800964-2) FUS3 [extracellular region] (R-SCE-6806250-2) FUS3 [azurophil granule lumen] (R-SCE-6799225-2) phospho-FUS3 [nucleoplasm] (R-SCE-5692665-2)	0.721	6
UniProt:P23561	1	STE11 [cytosol] (R-SCE-167709)	0.668	3
UniProt:P14681	20	phospho-KSS1 [nucleoplasm] (R-SCE-112354) phospho-KSS1 [nucleoplasm] (R-SCE-112359) phospho-KSS1 [cytosol] (R-SCE-109842) phospho-KSS1 [cytosol] (R-SCE-109853) KSS1 [cytosol] (R-SCE-59282) KSS1 [cytosol] (R-SCE-59284) KSS1 [nucleoplasm] (R-SCE-73724) KSS1 [nucleoplasm] (R-SCE-199960) phospho-KSS1 [cytosol] (R-SCE-9635773) phospho-KSS1 [cytosol] (R-SCE-9635775) KSS1 [cytosol] (R-SCE-4411330) phospho-KSS1 [cytosol] (R-SCE-4411398) phospho-KSS1 [nucleoplasm] (R-SCE-4411376) KSS1 [ficolin-1-rich granule lumen] (R-SCE-6800964) KSS1 [extracellular region] (R-SCE-6806250) KSS1 [azurophil granule lumen] (R-SCE-6799225) phospho-KSS1 [nucleoplasm] (R-SCE-5692665) KSS1 [nucleoplasm] (R-SCE-5692686) phospho-KSS1 [nucleoplasm] (R-SCE-5687015) phospho-KSS1 [nucleoplasm] (R-SCE-5687022)	0.667	6
UniProt:P11484	17	SSB1 [ficolin-1-rich granule lumen] (R-SCE-6801512-4) SSB1 [ficolin-1-rich granule lumen] (R-SCE-6801496-4) SSB1 [extracellular region] (R-SCE-6805872-4) SSB1 [extracellular region] (R-SCE-6806500-4) SSB1 [secretory granule lumen] (R-SCE-6801472-4) SSB1 [cytosol] (R-SCE-3371410-4) SSB1 [cytosol] (R-SCE-3371408-4) SSB1 [cytosol] (R-SCE-6792602-4) SSB1 [nucleoplasm] (R-SCE-6792605-4) SSB1 [nucleoplasm] (R-SCE-912480-4) SSB1 [nucleoplasm] (R-SCE-5082367-4) SSB1 [nucleoplasm] (R-SCE-5252082-4) SSB1 [nucleoplasm] (R-SCE-5252088-4) SSB1 [nucleoplasm] (R-SCE-5252009-4) SSB1 [cytosol] (R-SCE-5251948-4) SSB1 [cytosol] (R-SCE-5251981-4) SSB1 [cytosol] (R-SCE-3371521-4)	0.527	2
UniProt:P40073 SHO1			0.524	3
UniProt:P02829	11	HSP82 [cytosol] (R-SCE-192864) HSP82 [nucleoplasm] (R-SCE-5082399) HSP82 [nucleoplasm] (R-SCE-5082401) HSP82 [cytosol] (R-SCE-419617) HSP82 [plasma membrane] (R-SCE-534996) HSP82 [extracellular region] (R-SCE-3221946) HSP82 [ficolin-1-rich granule lumen] (R-SCE-6801491) HSP82 [ficolin-1-rich granule lumen] (R-SCE-6801470) HSP82 [extracellular region] (R-SCE-6806463) HSP82 [secretory granule lumen] (R-SCE-6801515) HSP82 [secretory granule lumen] (R-SCE-6801477)	0.488	2

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